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grant_code:"U24GM116788"

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Current Database

  • EMDB [8]

Current status

  • REL [8]

Sample type

  • Complex [7]
  • Protein [7]
  • RNA [6]
  • Ligand [2]
  • Cellular component [1]

Organism

  • Human respiratory syncytial virus [6]
  • Homo sapiens [1]
  • Bos taurus [1]

EM Method

  • Single-particle [8]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [7]

Model molecular weight

  • 100-250 kDa [1]
  • 250-500 kDa [6]

Release Date

  • 2026 [4]
  • 2023 [3]
  • 2020 [1]

Author by name

  • Cao D [6]
  • Chen Z [6]
  • Gao Y [6]
  • Gooneratne I [6]
  • Liang B [6]
  • Mera C [6]
  • Roesler C [6]
  • Berry J [4]
  • Nudell-cook E [4]
  • Royal M [4]
  • Shaik M [4]
  • Slack J [4]
  • Vy J [4]
  • Youngs R [4]
  • Zhuang L [4]
  • Wang Q [3]
  • Antonova A [2]
  • D Cunha P [2]
  • Jiang Q-X [2]
  • Katta D [2]
  • Lemons W [2]
  • Ramanathan A [2]
  • Rice S [2]
  • Romanelli S [2]
  • Yadav GP [2]
  • Cross S [1]
  • Jiang QX [1]
  • Li C [1]
  • Ouwendijk J [1]
  • Qin F [1]
  • Verkade P [1]
  • Wang H [1]
  • Zhou W [1]
  • Zhu MX [1]

Author by ORCID

  • Gao Y [6]
  • Cao D [6]
  • Liang B [6]
  • Gooneratne I [6]
  • Chen Z [4]
  • Yadav GP [2]
  • Katta D [2]
  • Verkade P [1]
  • Zhu MX [1]
  • Cross S [1]

Journal

  • NAT COMMUN [4]
  • NATURE [2]
  • FRONT MOL NEUROSCI [1]
  • TO BE PUBLISHED [1]

Software

  • COOT [4]
  • CRYOSPARC [1]
  • PHENIX [1]
  • RELION [1]
  • UCSF CHIMERAX [1]

Microscope

  • FEI TITAN KRIOS [4]
  • TFS KRIOS [4]

Electron Source

  • FIELD EMISSION GUN [8]

Film or detector model

  • GATAN K3 6K X 4K [6]
  • GATAN K2 SUMMIT 4K X 4K [1]
  • GATAN K3 BIOQUANTUM 6K X 4K [1]

External links

  • PDB [8]
  • PDBe-Kb [7]
  • UniProt [7]
  • Gene Ontology [3]
  • InterPro [3]
  • ChEBI [2]
  • DrugBank [2]
  • AlphaFold DB [1]
  • Complex Portal [1]
  • Pfam [1]
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EMD-71611
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3D View
Cryo-EM structure of the respiratory syncytial virus polymerase L:P in NTP-bound elongation state
CryoEM
Release date: May 6, 2026
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 9pfr
Q-score: 0.519

Cao D, Chen Z, Gao Y, Roesler C, Gooneratne I, Mera C, Zhuang L, Slack J, Nudell-Cook E, Vy J, Berry J, Royal M, Shaik M, Youngs R, Liang B

Nat Commun (2026) [ Pubmed: 42049741 DOI: doi:10.1038/s41467-026-72519-0 ]

EMD-71612
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3D View
Cryo-EM structure of the respiratory syncytial virus polymerase L:P in pre-reaction elongation state
CryoEM
Release date: May 6, 2026
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 9pfs
Q-score: 0.562

Cao D, Chen Z, Gao Y, Roesler C, Gooneratne I, Mera C, Zhuang L, Slack J, Nudell-Cook E, Vy J, Berry J, Royal M, Shaik M, Youngs R, Liang B

Nat Commun (2026) [ Pubmed: 42049741 DOI: doi:10.1038/s41467-026-72519-0 ]

EMD-71613
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3D View
Cryo-EM structure of the respiratory syncytial virus polymerase L:P in pre-translocation elongation state
CryoEM
Release date: May 6, 2026
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 9pft
Q-score: 0.545

Cao D, Chen Z, Gao Y, Roesler C, Gooneratne I, Mera C, Zhuang L, Slack J, Nudell-Cook E, Vy J, Berry J, Royal M, Shaik M, Youngs R, Liang B

Nat Commun (2026) [ Pubmed: 42049741 DOI: doi:10.1038/s41467-026-72519-0 ]

EMD-71614
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Cryo-EM structure of the respiratory syncytial virus polymerase L:P in post-translocation elongation state
CryoEM
Release date: May 6, 2026
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 9pfu
Q-score: 0.45

Cao D, Chen Z, Gao Y, Roesler C, Gooneratne I, Mera C, Zhuang L, Slack J, Nudell-Cook E, Vy J, Berry J, Royal M, Shaik M, Youngs R, Liang B

Nat Commun (2026) [ Pubmed: 42049741 DOI: doi:10.1038/s41467-026-72519-0 ]

EMD-40641
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Cryo-EM structure of the respiratory syncytial virus polymerase L:P bound to the leader promoter
CryoEM
Release date: Dec. 20, 2023
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8snx
Q-score: 0.523

Cao D, Gao Y, Chen Z, Gooneratne I, Roesler C, Mera C, D'Cunha P, Antonova A, Katta D, Romanelli S, Wang Q, Rice S, Lemons W, Ramanathan A, Liang B

Nature (2024) 625 pp. 611-617 [ Pubmed: 38123676 DOI: doi:10.1038/s41586-023-06867-y ]

EMD-40642
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Cryo-EM structure of the respiratory syncytial virus polymerase L:P bound to the trailer complementary promoter
CryoEM
Release date: Dec. 20, 2023
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8sny
Q-score: 0.483

Cao D, Gao Y, Chen Z, Gooneratne I, Roesler C, Mera C, D'Cunha P, Antonova A, Katta D, Romanelli S, Wang Q, Rice S, Lemons W, Ramanathan A, Liang B

Nature (2024) 625 pp. 611-617 [ Pubmed: 38123676 DOI: doi:10.1038/s41586-023-06867-y ]

EMD-36579
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A cryo-EM structure of the bovine chromogranin B dimer at a nominal resolution of 0.35 nm
CryoEM
Release date: July 26, 2023
Resolution: 3.5 Å
EM Method: Single-particle

Yadav GP, Wang H, Ouwendijk J, Cross S, Wang Q, Qin F, Verkade P, Zhu MX, Jiang QX

Front Mol Neurosci (2023) 16 pp. 1205516-1205516 [ Pubmed: 37435575 DOI: doi:10.3389/fnmol.2023.1205516 ]

EMD-20764
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Cryo-EM structure of the apo form of human PRMT5:MEP50 complex at a resolution of 3.4 angstrom.
CryoEM
Release date: Dec. 9, 2020
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6ugh
Q-score: 0.447

Zhou W, Yadav GP, Jiang Q-X, Li C

To Be Published

Sort by: Download
Showing 1 - 8 of 8. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [8]

Current status

  • REL [8]

Sample type

  • Complex [7]
  • Protein [7]
  • RNA [6]
  • Ligand [2]
  • Cellular component [1]

Organism

  • Human respiratory syncytial virus [6]
  • Homo sapiens [1]
  • Bos taurus [1]

EM Method

  • Single-particle [8]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [7]

Model molecular weight

  • 100-250 kDa [1]
  • 250-500 kDa [6]

Release Date

  • 2026 [4]
  • 2023 [3]
  • 2020 [1]

Author by name

  • Cao D [6]
  • Chen Z [6]
  • Gao Y [6]
  • Gooneratne I [6]
  • Liang B [6]
  • Mera C [6]
  • Roesler C [6]
  • Berry J [4]
  • Nudell-cook E [4]
  • Royal M [4]
  • Shaik M [4]
  • Slack J [4]
  • Vy J [4]
  • Youngs R [4]
  • Zhuang L [4]
  • Wang Q [3]
  • Antonova A [2]
  • D Cunha P [2]
  • Jiang Q-X [2]
  • Katta D [2]
  • Lemons W [2]
  • Ramanathan A [2]
  • Rice S [2]
  • Romanelli S [2]
  • Yadav GP [2]
  • Cross S [1]
  • Jiang QX [1]
  • Li C [1]
  • Ouwendijk J [1]
  • Qin F [1]
  • Verkade P [1]
  • Wang H [1]
  • Zhou W [1]
  • Zhu MX [1]

Author by ORCID

  • Gao Y [6]
  • Cao D [6]
  • Liang B [6]
  • Gooneratne I [6]
  • Chen Z [4]
  • Yadav GP [2]
  • Katta D [2]
  • Verkade P [1]
  • Zhu MX [1]
  • Cross S [1]

Journal

  • NAT COMMUN [4]
  • NATURE [2]
  • FRONT MOL NEUROSCI [1]
  • TO BE PUBLISHED [1]

Software

  • COOT [4]
  • CRYOSPARC [1]
  • PHENIX [1]
  • RELION [1]
  • UCSF CHIMERAX [1]

Microscope

  • FEI TITAN KRIOS [4]
  • TFS KRIOS [4]

Electron Source

  • FIELD EMISSION GUN [8]

Film or detector model

  • GATAN K3 6K X 4K [6]
  • GATAN K2 SUMMIT 4K X 4K [1]
  • GATAN K3 BIOQUANTUM 6K X 4K [1]

External links

  • PDB [8]
  • PDBe-Kb [7]
  • UniProt [7]
  • Gene Ontology [3]
  • InterPro [3]
  • ChEBI [2]
  • DrugBank [2]
  • AlphaFold DB [1]
  • Complex Portal [1]
  • Pfam [1]