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grant_code:"R35GM144120"

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Current Database

  • EMDB [26]

Current status

  • REL [26]

Sample type

  • Complex [26]
  • Protein [26]
  • Ligand [24]

Organism

  • Rattus norvegicus [11]
  • Oryctolagus cuniculus [9]
  • Homo sapiens [8]
  • Synthetic construct [2]

EM Method

  • Single-particle [26]

Resolution

  • ≥ 2Å and < 3Å [12]
  • ≥ 3Å and < 4Å [13]
  • ≥ 4Å and < 5Å [1]

Release Date

  • 2026 [9]
  • 2025 [7]
  • 2024 [7]
  • 2023 [3]

Author by name

  • Moiseenkova-bell VY [26]
  • Pumroy RA [18]
  • Rocereta JA [17]
  • De Jesus-Perez Jj [16]
  • Leffler A [16]
  • Moiseenkova-bell V [14]
  • Fricke TC [11]
  • Herzog C [11]
  • Rohacs T [10]
  • Pumroy RP [8]
  • Fluck EC [7]
  • Lee BH [7]
  • Hill K [6]
  • Sturhahn T [6]
  • Echtermeyer FG [5]
  • Meyer MJA [5]
  • Oprita G [5]
  • Protopopova AD [5]
  • Fricke T [4]
  • De Jesus Perez Jj [3]
  • Gabrielle M [3]
  • Raheem S [3]
  • Christensen CR [2]
  • Newstead S [2]
  • Salphati SP [2]
  • Chaudhuri A [1]
  • Danon JN [1]
  • Dasteh Goli K [1]
  • Hwang D [1]
  • Islas DL [1]
  • Leipe A [1]
  • Mallik L [1]
  • Mendez-resendiz A [1]
  • Moiseenkova-bell YV [1]
  • Rangel-yescas GE [1]
  • Rosenbaum T [1]
  • Schaefer M [1]
  • Sgourakis NG [1]
  • Sun Y [1]
  • Wang C [1]

Journal

  • NAT COMMUN [8]
  • NAT STRUCT MOL BIOL [6]
  • EMBO REP [4]
  • STRUCTURE [3]
  • TO BE PUBLISHED [3]
  • ACTA CRYSTALLOGR D STRUCT BIOL [2]
  • BR.J.PHARMACOL. [1]
  • PNAS [1]

Software

  • CRYOSPARC [15]
  • RELION [2]
  • CTFFIND [1]

Microscope

  • FEI TITAN KRIOS [19]
  • TFS GLACIOS [5]
  • TFS KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [26]

Film or detector model

  • GATAN K3 6K X 4K [21]
  • FEI FALCON IV 4K X 4K [5]

External links

  • AlphaFold DB [26]
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Showing 1 - 10 of 26. Page 1 of 3
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EMD-75707
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3D View
Apo human TRPV2, wild-type
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 11hz
Q-score: 0.49
Similar entry percentile: 67%

Fricke TC, Pumroy RA, Rocereta JA, De Jesus-Perez JJ, Oprita G, Meyer MJA, Herzog C, Echtermeyer FG, Hill K, Leffler A, Moiseenkova-Bell VY

Nat Commun (2026) 17 [ Pubmed: 42624855 DOI: doi:10.1038/s41467-026-76831-7 ]

EMD-75708
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3D View
Apo human TRPV2, S651H/T654D/D655N
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 11ia
Q-score: 0.607
Similar entry percentile: 90%

Fricke TC, Pumroy RA, Rocereta JA, De Jesus-Perez JJ, Oprita G, Meyer MJA, Herzog C, Echtermeyer FG, Hill K, Leffler A, Moiseenkova-Bell VY

Nat Commun (2026) 17 [ Pubmed: 42624855 DOI: doi:10.1038/s41467-026-76831-7 ]

EMD-75709
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3D View
2-APB bound human TRPV2, S651H/T654D/D655N
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 11ib
Q-score: 0.51
Similar entry percentile: 75%

Fricke TC, Pumroy RA, Rocereta JA, De Jesus-Perez JJ, Oprita G, Meyer MJA, Herzog C, Echtermeyer FG, Hill K, Leffler A, Moiseenkova-Bell VY

Nat Commun (2026) 17 [ Pubmed: 42624855 DOI: doi:10.1038/s41467-026-76831-7 ]

EMD-75711
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3D View
apo rat TRPV2, H651S/D654T/N655D
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 11id
Q-score: 0.569
Similar entry percentile: 85%

Fricke TC, Pumroy RA, Rocereta JA, De Jesus-Perez JJ, Oprita G, Meyer MJA, Herzog C, Echtermeyer FG, Hill K, Leffler A, Moiseenkova-Bell VY

Nat Commun (2026) 17 [ Pubmed: 42624855 DOI: doi:10.1038/s41467-026-76831-7 ]

EMD-75712
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3D View
2-APB bound rat TRPV2, H651S/D654T/N655D
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 11ie
Q-score: 0.553
Similar entry percentile: 83%

Fricke TC, Pumroy RA, Rocereta JA, De Jesus-Perez JJ, Oprita G, Meyer MJA, Herzog C, Echtermeyer FG, Hill K, Leffler A, Moiseenkova-Bell VY

Nat Commun (2026) 17 [ Pubmed: 42624855 DOI: doi:10.1038/s41467-026-76831-7 ]

EMD-70173
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Wildtype rabbit TRPV5 in nanodics in the presence of Menthol and PI 4,5 P2
CryoEM
Release date: April 22, 2026
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 9o6g

Mendez-Resendiz A, De Jesus-Perez JJ, Rangel-Yescas GE, Rosenbaum T, Moiseenkova-Bell VY, Islas DL

To Be Published

EMD-48325
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Rat TRPV2 bound to AV2-1 agonist
CryoEM
Release date: April 15, 2026
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 9mkf
Q-score: 0.559
Similar entry percentile: 76%

Leipe A, Rocereta JA, Pumroy RA, Leffler A, Schaefer M, Moiseenkova-Bell V, Hill K

Br.J.Pharmacol. (2026) 183 pp. 3538-3557 [ DOI: doi:10.1111/bph.70413 Pubmed: 41913383 ]

EMD-47874
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Human TRPML1 bound to Sybody94
CryoEM
Release date: Jan. 21, 2026
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9eb9

Salphati SP, Pumroy RP, Christensen CR, Moiseenkova-Bell VY, Newstead S

To Be Published

EMD-47875
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Human TRPML1 bound to Sybody57
CryoEM
Release date: Jan. 21, 2026
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9eba

Salphati SP, Pumroy RP, Christensen CR, Moiseenkova-Bell VY, Newstead S

To Be Published

EMD-44156
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Rat TRPV2 WT bound to probenecid
CryoEM
Release date: Feb. 26, 2025
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 9b3u
Q-score: 0.61
Similar entry percentile: 75%

Rocereta JA, Sturhahn T, Pumroy RA, Fricke TC, Herzog C, Leffler A, Moiseenkova-Bell V

Nat Struct Mol Biol (2025) 32 pp. 1019-1029 [ Pubmed: 39972168 DOI: doi:10.1038/s41594-025-01494-9 ]

Sort by: Download
Showing 1 - 10 of 26. Page 1 of 3
Display:
Statistics
×

Download


Preview 10 entries View All Download file

Filter By

Current Database

  • EMDB [26]

Current status

  • REL [26]

Sample type

  • Complex [26]
  • Protein [26]
  • Ligand [24]

Organism

  • Rattus norvegicus [11]
  • Oryctolagus cuniculus [9]
  • Homo sapiens [8]
  • Synthetic construct [2]

EM Method

  • Single-particle [26]

Resolution

  • ≥ 2Å and < 3Å [12]
  • ≥ 3Å and < 4Å [13]
  • ≥ 4Å and < 5Å [1]

Release Date

  • 2026 [9]
  • 2025 [7]
  • 2024 [7]
  • 2023 [3]

Author by name

  • Moiseenkova-bell VY [26]
  • Pumroy RA [18]
  • Rocereta JA [17]
  • De Jesus-Perez Jj [16]
  • Leffler A [16]
  • Moiseenkova-bell V [14]
  • Fricke TC [11]
  • Herzog C [11]
  • Rohacs T [10]
  • Pumroy RP [8]
  • Fluck EC [7]
  • Lee BH [7]
  • Hill K [6]
  • Sturhahn T [6]
  • Echtermeyer FG [5]
  • Meyer MJA [5]
  • Oprita G [5]
  • Protopopova AD [5]
  • Fricke T [4]
  • De Jesus Perez Jj [3]
  • Gabrielle M [3]
  • Raheem S [3]
  • Christensen CR [2]
  • Newstead S [2]
  • Salphati SP [2]
  • Chaudhuri A [1]
  • Danon JN [1]
  • Dasteh Goli K [1]
  • Hwang D [1]
  • Islas DL [1]
  • Leipe A [1]
  • Mallik L [1]
  • Mendez-resendiz A [1]
  • Moiseenkova-bell YV [1]
  • Rangel-yescas GE [1]
  • Rosenbaum T [1]
  • Schaefer M [1]
  • Sgourakis NG [1]
  • Sun Y [1]
  • Wang C [1]

Journal

  • NAT COMMUN [8]
  • NAT STRUCT MOL BIOL [6]
  • EMBO REP [4]
  • STRUCTURE [3]
  • TO BE PUBLISHED [3]
  • ACTA CRYSTALLOGR D STRUCT BIOL [2]
  • BR.J.PHARMACOL. [1]
  • PNAS [1]

Software

  • CRYOSPARC [15]
  • RELION [2]
  • CTFFIND [1]

Microscope

  • FEI TITAN KRIOS [19]
  • TFS GLACIOS [5]
  • TFS KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [26]

Film or detector model

  • GATAN K3 6K X 4K [21]
  • FEI FALCON IV 4K X 4K [5]

External links

  • AlphaFold DB [26]