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grant_code:"BB/M024709/1"

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Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • Ligand [5]
  • Protein [5]

Organism

  • Homo sapiens [5]
  • Lama glama [5]
  • Bos taurus [1]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 3Å and < 4Å [5]

Model molecular weight

  • 250-500 kDa [5]

Release Date

  • 2019 [5]

Author by name

  • Aricescu AR [5]
  • Desai R [5]
  • Karia D [5]
  • Kotecha A [5]
  • Laverty D [5]
  • Malinauskas T [5]
  • Masiulis S [5]
  • Miller KW [5]
  • Pardon E [5]
  • Serna Martin I [5]
  • Steyaert J [5]
  • Uchanski T [5]
  • Zivanov J [5]

Author by ORCID

  • Uchanski T [5]
  • Pardon E [5]
  • Steyaert J [5]
  • Kotecha A [5]
  • Malinauskas T [5]
  • Serna Martin I [5]
  • Aricescu AR [5]

Journal

  • NATURE [5]

Software

  • RELION [5]
  • GCTF [1]

Microscope

  • FEI TITAN KRIOS [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • FEI FALCON III 4K X 4K [4]
  • GATAN K2 SUMMIT 4K X 4K [1]

External links

  • AlphaFold DB [5]
  • ChEBI [5]
  • ChEMBL [5]
  • Complex Portal [5]
  • EMPIAR [5]
  • Gene Ontology [5]
  • InterPro [5]
  • PDB [5]
  • PDBe-Kb [5]
  • Pfam [5]
  • UniProt [5]
  • DrugBank [4]
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EMD-0275
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EMPIAR-11256
CryoEM structure of human full-length alpha1beta3gamma2L GABA A R in complex with picrotoxin and megabody Mb38.
Release date: Jan. 2, 2019
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6hug
Q-score: 0.55

Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

Nature (2019) 565 pp. 454-459 [ Pubmed: 30602790 DOI: doi:10.1038/s41586-018-0832-5 ]

EMD-0279
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Raw data
EMPIAR-11298
CryoEM structure of human full-length heteromeric alpha1beta3gamma2L GABA A R in complex with picrotoxin, GABA and megabody Mb38.
Release date: Jan. 2, 2019
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 6huj
Q-score: 0.541

Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

Nature (2019) 565 pp. 454-459 [ Pubmed: 30602790 DOI: doi:10.1038/s41586-018-0832-5 ]

EMD-0280
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Raw data
EMPIAR-11297
CryoEM structure of human full-length alpha1beta3gamma2L GABA A R in complex with bicuculline and megabody Mb38.
Release date: Jan. 2, 2019
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 6huk
Q-score: 0.455

Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

Nature (2019) 565 pp. 454-459 [ Pubmed: 30602790 DOI: doi:10.1038/s41586-018-0832-5 ]

EMD-0282
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3D View
Raw data
EMPIAR-11296
CryoEM structure of human full-length heteromeric alpha1beta3gamma2L GABA A R in complex with alprazolam Xanax , GABA and megabody Mb38.
Release date: Jan. 2, 2019
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 6huo
Q-score: 0.514

Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

Nature (2019) 565 pp. 454-459 [ Pubmed: 30602790 DOI: doi:10.1038/s41586-018-0832-5 ]

EMD-0283
Download Map
3D View
Raw data
EMPIAR-11295
CryoEM structure of human full-length alpha1beta3gamma2L GABA A R in complex with diazepam Valium , GABA and megabody Mb38.
Release date: Jan. 2, 2019
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 6hup
Q-score: 0.467

Masiulis S, Desai R, Uchanski T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

Nature (2019) 565 pp. 454-459 [ Pubmed: 30602790 DOI: doi:10.1038/s41586-018-0832-5 ]

Sort by: Download
Showing 1 - 5 of 5. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • Ligand [5]
  • Protein [5]

Organism

  • Homo sapiens [5]
  • Lama glama [5]
  • Bos taurus [1]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 3Å and < 4Å [5]

Model molecular weight

  • 250-500 kDa [5]

Release Date

  • 2019 [5]

Author by name

  • Aricescu AR [5]
  • Desai R [5]
  • Karia D [5]
  • Kotecha A [5]
  • Laverty D [5]
  • Malinauskas T [5]
  • Masiulis S [5]
  • Miller KW [5]
  • Pardon E [5]
  • Serna Martin I [5]
  • Steyaert J [5]
  • Uchanski T [5]
  • Zivanov J [5]

Author by ORCID

  • Uchanski T [5]
  • Pardon E [5]
  • Steyaert J [5]
  • Kotecha A [5]
  • Malinauskas T [5]
  • Serna Martin I [5]
  • Aricescu AR [5]

Journal

  • NATURE [5]

Software

  • RELION [5]
  • GCTF [1]

Microscope

  • FEI TITAN KRIOS [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • FEI FALCON III 4K X 4K [4]
  • GATAN K2 SUMMIT 4K X 4K [1]

External links

  • AlphaFold DB [5]
  • ChEBI [5]
  • ChEMBL [5]
  • Complex Portal [5]
  • EMPIAR [5]
  • Gene Ontology [5]
  • InterPro [5]
  • PDB [5]
  • PDBe-Kb [5]
  • Pfam [5]
  • UniProt [5]
  • DrugBank [4]