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author:"de la Cruz MJ"

Filter By

Current Database

  • EMDB [33]
  • EMPIAR [2]

Current status

  • REL [35]

Sample type

  • Protein [32]
  • Complex [17]
  • Ligand [17]
  • DNA [8]
  • Cellular component [7]
  • Sample [6]
  • Cell [3]
  • RNA [3]

Organism

  • Homo sapiens [11]
  • Vibrio cholerae [6]
  • Cryptococcus neoformans [4]
  • Cryptococcus neoformans [4]
  • Mus musculus [3]
  • Escherichia coli [3]
  • Parengyodontium album [2]
  • Bacillus thermoproteolyticus [1]
  • Mycolicibacterium smegmatis [1]
  • Synthetic construct [1]
  • Thaumatococcus daniellii [1]
  • Saccharomyces cerevisiae [1]
  • Hypocrea jecorina [1]
  • Gallus gallus [1]
  • Bos taurus [1]

EM Method

  • Single-particle [17]
  • Electron Crystallography [9]
  • Subtomogram averaging [4]
  • Helical reconstruction [3]

Resolution

  • < 2Å [5]
  • ≥ 2Å and < 3Å [7]
  • ≥ 3Å and < 4Å [11]
  • ≥ 4Å and < 5Å [1]
  • ≥ 8Å and < 12Å [4]
  • ≥ 16Å and < 20Å [1]
  • ≥ 20Å and < 30Å [4]

Model molecular weight

  • 0-50 kDa [9]
  • 50-100 kDa [1]
  • 100-250 kDa [4]
  • 250-500 kDa [9]

Release Date

  • 2026 [1]
  • 2025 [4]
  • 2024 [1]
  • 2022 [7]
  • 2021 [2]
  • 2020 [2]
  • 2019 [1]
  • 2018 [2]
  • 2016 [9]
  • 2015 [1]
  • 2014 [2]
  • 2011 [3]

Author by name

  • De La Cruz Mj [34]
  • Patel DJ [11]
  • Gonen T [9]
  • Hattne J [9]
  • Reyes FE [9]
  • Shi D [9]
  • Calero G [8]
  • Cascio D [8]
  • Eisenberg D [8]
  • Hinck AP [8]
  • Hinck CS [8]
  • Kim SK [8]
  • Rodriguez J [8]
  • Sawaya MR [8]
  • Seidler P [8]
  • Weiss SC [8]
  • Yu Z [8]
  • Wang J [7]
  • Chait BT [6]
  • Ahmed MA [4]
  • Bernheim A [4]
  • Catania S [4]
  • Chakravarti A [4]
  • Haudiquet M [4]
  • Herrero Del Valle A [4]
  • Lavenir R [4]
  • Madhani HD [4]
  • Olinares PDB [4]
  • Ramirez JL [4]
  • Rao B [4]
  • Sternberg SH [4]
  • Wang C [4]
  • Zhang Z [4]
  • Akey CW [3]
  • Bartesaghi A [3]
  • Bess JW [3]
  • Borgnia M [3]
  • Borgnia MJ [3]
  • Borkowski B [3]
  • Broeck AV [3]
  • Chen ZJ [3]
  • Feng W [3]
  • Fernandez-martinez J [3]
  • He X [3]
  • Hite RK [3]
  • Hoover EA [3]
  • Hou F [3]
  • Hoxie JA [3]
  • Huang LJ [3]
  • Jiang Q-X [3]
  • Jiang QX [3]
  • Karthaus WR [3]
  • Klinge S [3]
  • Laclair JR [3]
  • Lawrence KE [3]
  • Lifson JD [3]
  • Ludtke SJ [3]
  • Manova-todorova K [3]
  • Matthies D [3]
  • Meyerson JR [3]
  • Milne JL [3]
  • Nandwani R [3]
  • Nudelman I [3]
  • Paknejad N [3]
  • Pappas K [3]
  • Rout MP [3]
  • Sawyers CL [3]
  • Subramaniam S [3]
  • Vanden Broeck A [3]
  • Wang B [3]
  • Wasmuth EV [3]
  • Watson PA [3]
  • Weintraub ST [3]
  • White TA [3]
  • Xie W [3]
  • Xu H [3]
  • Zhang X [3]
  • Zheng H [3]
  • Zinder JC [3]
  • Aitchison JD [2]
  • Chaudhury AS [2]
  • Chemmama IE [2]
  • Echeverria I [2]
  • Eng ET [2]
  • Gerton JL [2]
  • Goldgur Y [2]
  • Greenberg CH [2]
  • Herricks T [2]
  • Hogan JA [2]
  • Jacobs EY [2]
  • Jarrold MF [2]
  • Jia N [2]
  • Kim SJ [2]
  • Mironska R [2]
  • Pellarin R [2]
  • Raveh B [2]
  • Sali A [2]
  • Shi Y [2]
  • Shivaraju M [2]
  • Slaughter BD [2]

Author by ORCID

  • De La Cruz Mj [21]
  • Hattne J [9]
  • Sawaya MR [8]
  • Patel DJ [5]
  • Madhani HD [4]
  • Herrero Del Valle A [4]
  • Sternberg SH [4]
  • Haudiquet M [4]
  • Olinares PDB [4]
  • Chait BT [4]
  • Catania S [4]
  • Chakravarti A [4]
  • White TA [3]
  • Borgnia MJ [3]
  • Chen ZJ [3]
  • Karthaus WR [3]
  • Subramaniam S [3]
  • Zinder JC [3]
  • Jia N [2]
  • Hou F [2]
  • Eng ET [2]
  • He X [2]
  • Xu G [1]
  • Shivaraju M [1]
  • Jarrold MF [1]
  • Ludtke SJ [1]
  • Chaudhury AS [1]
  • Raveh B [1]
  • Shi Y [1]
  • Akey CW [1]
  • Xie W [1]
  • Scaltriti M [1]
  • Chemmama IE [1]
  • Love TM [1]
  • Fernandez-martinez J [1]
  • Wang J [1]
  • Unruh JR [1]
  • Echeverria I [1]
  • Brockmann EC [1]

Journal

  • NAT METHODS [8]
  • MOL CELL [7]
  • PNAS [5]
  • ELIFE [3]
  • NATURE [3]
  • PLOS PATHOG [3]
  • CELL RES [2]
  • BIOMED PHARMACOTHER [1]
  • J AM CHEM SOC [1]
  • J APPL CRYSTALLOGR [1]
  • RNA [1]

Software

  • RELION [9]
  • AIMLESS [8]
  • POINTLESS [8]
  • MOLREP [7]
  • CRYOSPARC [4]
  • IMOD [3]
  • UCSF CHIMERA [3]
  • SPIDER, MRC, EMAN, IMAGIC4D [2]
  • CHIMERA [1]
  • CHIMERA, SITUS [1]
  • EMAN2 [1]
  • PHASER [1]
  • RELION, IHRSR [1]
  • XDS [1]

Microscope

  • FEI TITAN KRIOS [13]
  • FEI TECNAI F20 [9]
  • TFS KRIOS [6]
  • FEI POLARA 300 [3]
  • JEOL 2200FS [2]

Electron Source

  • FIELD EMISSION GUN [33]

Film or detector model

  • GATAN K3 6K X 4K [11]
  • TVIPS TEMCAM-F416 4K X 4K [9]
  • GATAN K3 BIOQUANTUM 6K X 4K [4]
  • GENERIC GATAN [3]
  • KODAK SO-163 FILM [2]
  • FEI FALCON II 4K X 4K [1]
  • FEI FALCON IV 4K X 4K [1]
  • GATAN K2 SUMMIT 4K X 4K [1]
  • TFS FALCON 4I 4K X 4K [1]

EMPIAR Experiment type

  • EMDB [2]

EMPIAR Image category

  • MICROGRAPHS - SINGLE FRAME [2]
  • CLASS AVERAGES [1]

External links

  • PDB [32]
  • AlphaFold DB [27]
  • UniProt [27]
  • PDBe-Kb [23]
  • InterPro [17]
  • ChEBI [16]
  • DrugBank [16]
  • Gene Ontology [16]
  • ChEMBL [15]
  • CATH [8]
  • Pfam [6]
  • EMPIAR [4]
  • EMDB [2]
  • Complex Portal [1]
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Showing 1 - 10 of 35. Page 1 of 4
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EMD-73971
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3D View
HMG-CoA synthase 1 HMGCS1 bound to inhibitor compound CNP7
CryoEM
Release date: May 27, 2026
Resolution: 2.29 Å
EM Method: Single-particle
Fitted PDBs: 9zaw
Q-score: 0.652

Sun L, Yi SA, Pham BQ, Mocellin A, Sen S, de la Cruz MJ, Ordureau A, An H

J Am Chem Soc (2026) 148 pp. 20705-20719 [ DOI: doi:10.1021/jacs.6c02556 Pubmed: 42127206 ]

EMD-49911
Download Map
3D View
LmuA_conformation 1
CryoEM
Release date: Dec. 17, 2025
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 9nxx
Q-score: 0.496

Haudiquet M, Chakravarti A, Zhang Z, Ramirez JL, Herrero Del Valle A, Olinares PDB, Lavenir R, Ahmed MA, de la Cruz MJ, Chait BT, Sternberg SH, Bernheim A, Patel DJ

PNAS (2025) 122 pp. e2519643122-e2519643122 [ Pubmed: 41252147 DOI: doi:10.1073/pnas.2519643122 ]

EMD-49915
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3D View
LmuA_conformation 2_assymetric
CryoEM
Release date: Dec. 17, 2025
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 9ny1
Q-score: 0.407

Haudiquet M, Chakravarti A, Zhang Z, Ramirez JL, Herrero Del Valle A, Olinares PDB, Lavenir R, Ahmed MA, de la Cruz MJ, Chait BT, Sternberg SH, Bernheim A, Patel DJ

PNAS (2025) 122 pp. e2519643122-e2519643122 [ Pubmed: 41252147 DOI: doi:10.1073/pnas.2519643122 ]

EMD-49922
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3D View
LmuABC_apo
CryoEM
Release date: Dec. 17, 2025
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 9ny5
Q-score: 0.418

Haudiquet M, Chakravarti A, Zhang Z, Ramirez JL, Herrero Del Valle A, Olinares PDB, Lavenir R, Ahmed MA, de la Cruz MJ, Chait BT, Sternberg SH, Bernheim A, Patel DJ

PNAS (2025) 122 pp. e2519643122-e2519643122 [ Pubmed: 41252147 DOI: doi:10.1073/pnas.2519643122 ]

EMD-49934
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3D View
LmuABC-DNA
CryoEM
Release date: Dec. 17, 2025
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 9nyg
Q-score: 0.374

Haudiquet M, Chakravarti A, Zhang Z, Ramirez JL, Herrero Del Valle A, Olinares PDB, Lavenir R, Ahmed MA, de la Cruz MJ, Chait BT, Sternberg SH, Bernheim A, Patel DJ

PNAS (2025) 122 pp. e2519643122-e2519643122 [ Pubmed: 41252147 DOI: doi:10.1073/pnas.2519643122 ]

EMD-47571
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3D View
Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells.
CryoEM
Release date: Nov. 20, 2024
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 9e6k
Q-score: 0.473

Saha N, Lee SG, Brockmann EC, de la Cruz MJ, Goldgur Y, Mendoza RP, Stanchina E, Love TM, Marvald J, Xu Y, Xu K, Himanen JP, Lamminmaki U, Veach D, Nikolov DB

Biomed Pharmacother (2024) 180 pp. 117605-117605 [ Pubmed: 39461016 DOI: doi:10.1016/j.biopha.2024.117605 ]

EMD-25132
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3D View
Androgen receptor bound to DNA - Entrenched state
CryoEM
Release date: May 4, 2022
Resolution: 11.4 Å
EM Method: Single-particle

Wasmuth EV, Broeck AV, LaClair JR, Hoover EA, Lawrence KE, Paknejad N, Pappas K, Matthies D, Wang B, Feng W, Watson PA, Zinder JC, Karthaus WR, de la Cruz MJ, Hite RK, Manova-Todorova K, Yu Z, Weintraub ST, Klinge S, Sawyers CL

Mol Cell (2022) 82 pp. 2021-2031.e5 [ Pubmed: 35447082 DOI: doi:10.1016/j.molcel.2022.03.035 ]

EMD-25133
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Androgen receptor bound to DNA - Splayed state
CryoEM
Release date: May 4, 2022
Resolution: 9.1 Å
EM Method: Single-particle

Wasmuth EV, Broeck AV, LaClair JR, Hoover EA, Lawrence KE, Paknejad N, Pappas K, Matthies D, Wang B, Feng W, Watson PA, Zinder JC, Karthaus WR, de la Cruz MJ, Hite RK, Manova-Todorova K, Yu Z, Weintraub ST, Klinge S, Sawyers CL

Mol Cell (2022) 82 pp. 2021-2031.e5 [ Pubmed: 35447082 DOI: doi:10.1016/j.molcel.2022.03.035 ]

EMD-25134
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3D View
Androgen receptor bound to DNA - Divorced state
CryoEM
Release date: May 4, 2022
Resolution: 9.4 Å
EM Method: Single-particle

Wasmuth EV, Broeck AV, LaClair JR, Hoover EA, Lawrence KE, Paknejad N, Pappas K, Matthies D, Wang B, Feng W, Watson PA, Zinder JC, Karthaus WR, de la Cruz MJ, Hite RK, Manova-Todorova K, Yu Z, Weintraub ST, Klinge S, Sawyers CL

Mol Cell (2022) 82 pp. 2021-2031.e5 [ Pubmed: 35447082 DOI: doi:10.1016/j.molcel.2022.03.035 ]

EMD-24292
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Cryo-EM structure of DNMT5 in apo state
CryoEM
Release date: Feb. 23, 2022
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7r76
Q-score: 0.479

Wang J, Catania S, Wang C, de la Cruz MJ, Rao B, Madhani HD, Patel DJ

Mol Cell (2022) 82 pp. 1186-1198.e6 [ Pubmed: 35202575 DOI: doi:10.1016/j.molcel.2022.01.028 ]

Sort by: Download
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Filter By

Current Database

  • EMDB [33]
  • EMPIAR [2]

Current status

  • REL [35]

Sample type

  • Protein [32]
  • Complex [17]
  • Ligand [17]
  • DNA [8]
  • Cellular component [7]
  • Sample [6]
  • Cell [3]
  • RNA [3]

Organism

  • Homo sapiens [11]
  • Vibrio cholerae [6]
  • Cryptococcus neoformans [4]
  • Cryptococcus neoformans [4]
  • Mus musculus [3]
  • Escherichia coli [3]
  • Parengyodontium album [2]
  • Bacillus thermoproteolyticus [1]
  • Mycolicibacterium smegmatis [1]
  • Synthetic construct [1]
  • Thaumatococcus daniellii [1]
  • Saccharomyces cerevisiae [1]
  • Hypocrea jecorina [1]
  • Gallus gallus [1]
  • Bos taurus [1]

EM Method

  • Single-particle [17]
  • Electron Crystallography [9]
  • Subtomogram averaging [4]
  • Helical reconstruction [3]

Resolution

  • < 2Å [5]
  • ≥ 2Å and < 3Å [7]
  • ≥ 3Å and < 4Å [11]
  • ≥ 4Å and < 5Å [1]
  • ≥ 8Å and < 12Å [4]
  • ≥ 16Å and < 20Å [1]
  • ≥ 20Å and < 30Å [4]

Model molecular weight

  • 0-50 kDa [9]
  • 50-100 kDa [1]
  • 100-250 kDa [4]
  • 250-500 kDa [9]

Release Date

  • 2026 [1]
  • 2025 [4]
  • 2024 [1]
  • 2022 [7]
  • 2021 [2]
  • 2020 [2]
  • 2019 [1]
  • 2018 [2]
  • 2016 [9]
  • 2015 [1]
  • 2014 [2]
  • 2011 [3]

Author by name

  • De La Cruz Mj [34]
  • Patel DJ [11]
  • Gonen T [9]
  • Hattne J [9]
  • Reyes FE [9]
  • Shi D [9]
  • Calero G [8]
  • Cascio D [8]
  • Eisenberg D [8]
  • Hinck AP [8]
  • Hinck CS [8]
  • Kim SK [8]
  • Rodriguez J [8]
  • Sawaya MR [8]
  • Seidler P [8]
  • Weiss SC [8]
  • Yu Z [8]
  • Wang J [7]
  • Chait BT [6]
  • Ahmed MA [4]
  • Bernheim A [4]
  • Catania S [4]
  • Chakravarti A [4]
  • Haudiquet M [4]
  • Herrero Del Valle A [4]
  • Lavenir R [4]
  • Madhani HD [4]
  • Olinares PDB [4]
  • Ramirez JL [4]
  • Rao B [4]
  • Sternberg SH [4]
  • Wang C [4]
  • Zhang Z [4]
  • Akey CW [3]
  • Bartesaghi A [3]
  • Bess JW [3]
  • Borgnia M [3]
  • Borgnia MJ [3]
  • Borkowski B [3]
  • Broeck AV [3]
  • Chen ZJ [3]
  • Feng W [3]
  • Fernandez-martinez J [3]
  • He X [3]
  • Hite RK [3]
  • Hoover EA [3]
  • Hou F [3]
  • Hoxie JA [3]
  • Huang LJ [3]
  • Jiang Q-X [3]
  • Jiang QX [3]
  • Karthaus WR [3]
  • Klinge S [3]
  • Laclair JR [3]
  • Lawrence KE [3]
  • Lifson JD [3]
  • Ludtke SJ [3]
  • Manova-todorova K [3]
  • Matthies D [3]
  • Meyerson JR [3]
  • Milne JL [3]
  • Nandwani R [3]
  • Nudelman I [3]
  • Paknejad N [3]
  • Pappas K [3]
  • Rout MP [3]
  • Sawyers CL [3]
  • Subramaniam S [3]
  • Vanden Broeck A [3]
  • Wang B [3]
  • Wasmuth EV [3]
  • Watson PA [3]
  • Weintraub ST [3]
  • White TA [3]
  • Xie W [3]
  • Xu H [3]
  • Zhang X [3]
  • Zheng H [3]
  • Zinder JC [3]
  • Aitchison JD [2]
  • Chaudhury AS [2]
  • Chemmama IE [2]
  • Echeverria I [2]
  • Eng ET [2]
  • Gerton JL [2]
  • Goldgur Y [2]
  • Greenberg CH [2]
  • Herricks T [2]
  • Hogan JA [2]
  • Jacobs EY [2]
  • Jarrold MF [2]
  • Jia N [2]
  • Kim SJ [2]
  • Mironska R [2]
  • Pellarin R [2]
  • Raveh B [2]
  • Sali A [2]
  • Shi Y [2]
  • Shivaraju M [2]
  • Slaughter BD [2]

Author by ORCID

  • De La Cruz Mj [21]
  • Hattne J [9]
  • Sawaya MR [8]
  • Patel DJ [5]
  • Madhani HD [4]
  • Herrero Del Valle A [4]
  • Sternberg SH [4]
  • Haudiquet M [4]
  • Olinares PDB [4]
  • Chait BT [4]
  • Catania S [4]
  • Chakravarti A [4]
  • White TA [3]
  • Borgnia MJ [3]
  • Chen ZJ [3]
  • Karthaus WR [3]
  • Subramaniam S [3]
  • Zinder JC [3]
  • Jia N [2]
  • Hou F [2]
  • Eng ET [2]
  • He X [2]
  • Xu G [1]
  • Shivaraju M [1]
  • Jarrold MF [1]
  • Ludtke SJ [1]
  • Chaudhury AS [1]
  • Raveh B [1]
  • Shi Y [1]
  • Akey CW [1]
  • Xie W [1]
  • Scaltriti M [1]
  • Chemmama IE [1]
  • Love TM [1]
  • Fernandez-martinez J [1]
  • Wang J [1]
  • Unruh JR [1]
  • Echeverria I [1]
  • Brockmann EC [1]

Journal

  • NAT METHODS [8]
  • MOL CELL [7]
  • PNAS [5]
  • ELIFE [3]
  • NATURE [3]
  • PLOS PATHOG [3]
  • CELL RES [2]
  • BIOMED PHARMACOTHER [1]
  • J AM CHEM SOC [1]
  • J APPL CRYSTALLOGR [1]
  • RNA [1]

Software

  • RELION [9]
  • AIMLESS [8]
  • POINTLESS [8]
  • MOLREP [7]
  • CRYOSPARC [4]
  • IMOD [3]
  • UCSF CHIMERA [3]
  • SPIDER, MRC, EMAN, IMAGIC4D [2]
  • CHIMERA [1]
  • CHIMERA, SITUS [1]
  • EMAN2 [1]
  • PHASER [1]
  • RELION, IHRSR [1]
  • XDS [1]

Microscope

  • FEI TITAN KRIOS [13]
  • FEI TECNAI F20 [9]
  • TFS KRIOS [6]
  • FEI POLARA 300 [3]
  • JEOL 2200FS [2]

Electron Source

  • FIELD EMISSION GUN [33]

Film or detector model

  • GATAN K3 6K X 4K [11]
  • TVIPS TEMCAM-F416 4K X 4K [9]
  • GATAN K3 BIOQUANTUM 6K X 4K [4]
  • GENERIC GATAN [3]
  • KODAK SO-163 FILM [2]
  • FEI FALCON II 4K X 4K [1]
  • FEI FALCON IV 4K X 4K [1]
  • GATAN K2 SUMMIT 4K X 4K [1]
  • TFS FALCON 4I 4K X 4K [1]

EMPIAR Experiment type

  • EMDB [2]

EMPIAR Image category

  • MICROGRAPHS - SINGLE FRAME [2]
  • CLASS AVERAGES [1]

External links

  • PDB [32]
  • AlphaFold DB [27]
  • UniProt [27]
  • PDBe-Kb [23]
  • InterPro [17]
  • ChEBI [16]
  • DrugBank [16]
  • Gene Ontology [16]
  • ChEMBL [15]
  • CATH [8]
  • Pfam [6]
  • EMPIAR [4]
  • EMDB [2]
  • Complex Portal [1]