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author:"Topf M"

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Current Database

  • EMDB [77]

Current status

  • REL [77]

Sample type

  • Protein [63]
  • Complex [41]
  • Sample [34]
  • Ligand [28]
  • RNA [8]
  • Virus [7]

Organism

  • Homo sapiens [25]
  • Bos taurus [19]
  • Escherichia coli [12]
  • Synthetic construct [7]
  • Sus scrofa [7]
  • Mus musculus [6]
  • Oceanobacillus iheyensis [6]
  • Human herpesvirus 1 [4]
  • Pleurotus ostreatus [4]
  • Bacillus phage spp1 [3]
  • Saccharomyces cerevisiae [3]
  • Oryctolagus cuniculus [3]
  • Human herpesvirus 1 [2]
  • Simplexvirus humanalpha2 [2]
  • Streptococcus suis [2]
  • Vicugna pacos [2]
  • Enterovirus a [2]
  • Pseudomonas monteilii [2]
  • Plasmodium falciparum [1]
  • Plasmodium falciparum [1]
  • Drosophila melanogaster [1]
  • Canis lupus [1]

EM Method

  • Single-particle [66]
  • Helical reconstruction [7]
  • Subtomogram averaging [4]

Resolution

  • ≥ 2Å and < 3Å [7]
  • ≥ 3Å and < 4Å [6]
  • ≥ 4Å and < 5Å [18]
  • ≥ 5Å and < 6Å [7]
  • ≥ 6Å and < 8Å [15]
  • ≥ 8Å and < 12Å [14]
  • ≥ 12Å and < 16Å [6]
  • ≥ 16Å and < 20Å [1]
  • ≥ 20Å and < 30Å [2]
  • ≥ 30Å [1]

Model molecular weight

  • 50-100 kDa [8]
  • 100-250 kDa [29]
  • 250-500 kDa [5]
  • 500-1000 kDa [8]
  • 1-2 MDa [7]
  • 2-5 MDa [3]
  • > 10 MDa [3]

Release Date

  • 2026 [3]
  • 2025 [10]
  • 2023 [2]
  • 2022 [1]
  • 2021 [2]
  • 2020 [3]
  • 2019 [3]
  • 2018 [7]
  • 2017 [12]
  • 2016 [3]
  • 2015 [6]
  • 2014 [7]
  • 2013 [2]
  • 2012 [9]
  • 2011 [2]
  • 2010 [3]
  • 2009 [2]

Author by name

  • Topf M [77]
  • Moores CA [21]
  • Saibil HR [20]
  • Atherton J [19]
  • Joseph AP [15]
  • Farabella I [13]
  • Mulvaney T [13]
  • Clare DK [11]
  • Houdusse A [11]
  • Rosenfeld SS [11]
  • Yu IM [11]
  • Lukoyanova N [9]
  • Vasishtan D [9]
  • Grunewald K [8]
  • Boyd CM [7]
  • Brooks NJ [7]
  • Bubeck D [7]
  • Farr GW [7]
  • Gardner S [7]
  • Horwich AL [7]
  • Menny A [7]
  • Moores C [7]
  • Morgan BP [7]
  • Pandurangan AP [7]
  • Quispe J [7]
  • Serna M [7]
  • Stagg S [7]
  • De Vivo M [6]
  • Dunstone MA [6]
  • Jadhav S [6]
  • Jadhav SS [6]
  • Maiorca M [6]
  • Manigrasso J [6]
  • Marcia M [6]
  • Muscat S [6]
  • Rakitch A [6]
  • Reboul CF [6]
  • Saha S [6]
  • Vollmer B [6]
  • Boyd CB [5]
  • Gardener S [5]
  • Mielke T [5]
  • Pena A [5]
  • Roberts AJ [5]
  • Trapani JA [5]
  • Voskoboinik I [5]
  • Caradoc-davies TT [4]
  • Clause J [4]
  • Cook A [4]
  • Cook AD [4]
  • Ebel H [4]
  • Ekkel S [4]
  • Ekkel SM [4]
  • Gorlich D [4]
  • Gruenewald K [4]
  • Hatfaludi T [4]
  • Hotze EM [4]
  • Joseph A [4]
  • Kleifeld O [4]
  • Kondos SC [4]
  • Krull J [4]
  • Law RH [4]
  • Law RHP [4]
  • Major J [4]
  • Muretta JM [4]
  • Nentwig J [4]
  • Oliver K [4]
  • Perugini M [4]
  • Rees R [4]
  • Schunemann J [4]
  • Sourigues Y [4]
  • Spicer BA [4]
  • Traore DA [4]
  • Tweten RK [4]
  • Whisstock JC [4]
  • Abis G [3]
  • Akey CW [3]
  • Akhmanova A [3]
  • Baldus M [3]
  • Brasiles S [3]
  • Burger J [3]
  • Chu LY [3]
  • Conte MR [3]
  • El Sadek Fadel M [3]
  • Eswar N [3]
  • Gordon-weeks PR [3]
  • Grant BJ [3]
  • Houben K [3]
  • Hua S [3]
  • Ignatiou A [3]
  • Jiang K [3]
  • Locke J [3]
  • Luo Y [3]
  • Malhotra S [3]
  • Mayer TU [3]
  • Mockel MM [3]
  • Nagar N [3]
  • Oozeer F [3]
  • Orlova EV [3]
  • Scarabelli G [3]

Author by ORCID

  • Topf M [14]
  • Mulvaney T [9]
  • Muscat S [6]
  • Marcia M [6]
  • De Vivo M [6]
  • Manigrasso J [6]
  • Saha S [6]
  • Conte MR [3]
  • Mielke T [3]
  • Saibil HR [3]
  • Gordon-weeks PR [3]
  • Atherton J [3]
  • Oozeer F [3]
  • Abis G [3]
  • Orlova EV [3]
  • Zhao W [3]
  • Bubeck D [2]
  • Zhao JZ [2]
  • Sethi A [2]
  • Brooks NJ [2]
  • Nelson ME [2]
  • Kassa A [2]
  • Leininger C [2]
  • Eswar N [2]
  • Lukoyanova N [1]
  • Malhotra S [1]
  • Voskoboinik I [1]
  • Trapani JA [1]

Journal

  • NAT COMMUN [21]
  • ELIFE [13]
  • CELL [7]
  • STRUCTURE [7]
  • NAT STRUCT MOL BIOL [4]
  • NATURE [4]
  • PLOS BIOL [4]
  • PNAS [4]
  • SCI ADV [4]
  • J BIOL CHEM [3]
  • EMBO REP [2]
  • J VIROL [2]
  • METHODS [2]
  • TO BE PUBLISHED [1]

Software

  • RELION [14]
  • CRYOSPARC [11]
  • CTFFIND [10]
  • SPIDER [8]
  • CHIMERA [7]
  • CHIMERA, FLEX-EM [7]
  • SPIDER, FREALIGN [7]
  • SPIDER, IMAGIC [7]
  • CHIMERA, FLEX-EM, NAMD2.6 [6]
  • FREALIGN [6]
  • FLEX-EM [4]
  • IMAGIC, SPIDER [4]
  • CHIMERA, FLEX-EM, MODELLER, TEMPY [3]
  • IMAGIC [3]
  • AUTO3DEM [2]
  • EMAN [2]
  • IMAGIC-5, SPIDER [2]
  • JSUBTOMO [2]
  • RELION, CTFFIND3 [2]
  • SPIDER, IMAGIC, EMAN [2]
  • 3DMOD [1]
  • CHIMERA, FLEX-EM, ADP-EM, GMFIT, TEMPY [1]
  • CHIMERA, FLEX-EM, MODELLER [1]
  • EMAN2 [1]
  • IMOD, PEET [1]
  • MOD-EM AND FLEX-EM [1]
  • PEET [1]
  • SITUS [1]

Microscope

  • FEI POLARA 300 [32]
  • FEI TITAN KRIOS [19]
  • FEI TECNAI F20 [15]
  • TFS KRIOS [9]
  • FEI TECNAI 20 [1]
  • FEI TECNAI F30 [1]

Electron Source

  • FIELD EMISSION GUN [77]

Film or detector model

  • GATAN ULTRASCAN 4000 4K X 4K [22]
  • GATAN K2 SUMMIT 4K X 4K [17]
  • FEI FALCON II 4K X 4K [7]
  • DIRECT ELECTRON DE-20 5K X 3K [6]
  • KODAK SO-163 FILM [6]
  • GATAN K3 BIOQUANTUM 6K X 4K [5]
  • GATAN K2 QUANTUM 4K X 4K [4]
  • GATAN K2 BASE 4K X 4K [2]
  • GATAN K3 6K X 4K [2]
  • GENERIC GATAN 4K X 4K [2]
  • TFS FALCON 4I 4K X 4K [2]
  • FEI FALCON IV 4K X 4K [1]
  • GENERIC TVIPS 4K X 4K [1]

External links

  • PDB [63]
  • UniProt [52]
  • PDBe-Kb [43]
  • AlphaFold DB [39]
  • InterPro [31]
  • Gene Ontology [29]
  • Pfam [23]
  • ChEBI [22]
  • ChEMBL [20]
  • DrugBank [20]
  • Complex Portal [6]
  • SCOP2 [2]
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EMD-55893
Download Map
3D View
Drebrin actin binding domain 1 conformation A ABD1a bound to F-actin
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 9tg8
Q-score: 0.628
Similar entry percentile: 78%

Zhao W, Chu LY, Abis G, Oozeer F, Mulvaney T, Nagar N, Topf M, Gordon-Weeks PR, Conte MR, Atherton J

Nat Commun (2026) 17 [ Pubmed: 42337253 DOI: doi:10.1038/s41467-026-74543-6 ]

EMD-55894
Download Map
3D View
Drebrin actin binding domain 1 conformation B ABD1b bound to F-actin
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.34 Å
EM Method: Single-particle
Fitted PDBs: 9tg9
Q-score: 0.644
Similar entry percentile: 83%

Zhao W, Chu LY, Abis G, Oozeer F, Mulvaney T, Nagar N, Topf M, Gordon-Weeks PR, Conte MR, Atherton J

Nat Commun (2026) 17 [ Pubmed: 42337253 DOI: doi:10.1038/s41467-026-74543-6 ]

EMD-55895
Download Map
3D View
Drebrin actin binding domain 2 bound to F-actin
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.29 Å
EM Method: Single-particle
Fitted PDBs: 9tga
Q-score: 0.664
Similar entry percentile: 85%

Zhao W, Chu LY, Abis G, Oozeer F, Mulvaney T, Nagar N, Topf M, Gordon-Weeks PR, Conte MR, Atherton J

Nat Commun (2026) 17 [ Pubmed: 42337253 DOI: doi:10.1038/s41467-026-74543-6 ]

EMD-51080
Download Map
3D View
Group II intron assembly intermediate Domain 1, 2, 3 and 4 Fully open state
CryoEM
Release date: Dec. 17, 2025
Resolution: 7.54 Å
EM Method: Single-particle
Fitted PDBs: 9g56
Q-score: 0.123
Similar entry percentile: 41%

Jadhav S, Maiorca M, Manigrasso J, Saha S, Rakitch A, Muscat S, Mulvaney T, De Vivo M, Topf M, Marcia M

Nat Commun (2025) 16 pp. 10195-10195 [ DOI: doi:10.1038/s41467-025-65502-8 Pubmed: 41309593 ]

EMD-51040
Download Map
3D View
Group II intron assembly intermediate Domain 1 and 2 Partly open state
CryoEM
Release date: Nov. 5, 2025
Resolution: 4.61 Å
EM Method: Single-particle
Fitted PDBs: 9g4i
Q-score: 0.257
Similar entry percentile: 44%

Jadhav S, Maiorca M, Manigrasso J, Saha S, Rakitch A, Muscat S, Mulvaney T, De Vivo M, Topf M, Marcia M

Nat Commun (2025) 16 pp. 10195-10195 [ DOI: doi:10.1038/s41467-025-65502-8 Pubmed: 41309593 ]

EMD-51041
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3D View
Group II intron assembly intermediate Domain 1 to 3 Fully open state
CryoEM
Release date: Nov. 5, 2025
Resolution: 3.74 Å
EM Method: Single-particle
Fitted PDBs: 9g4j
Q-score: 0.307
Similar entry percentile: 16%

Jadhav S, Maiorca M, Manigrasso J, Saha S, Rakitch A, Muscat S, Mulvaney T, De Vivo M, Topf M, Marcia M

Nat Commun (2025) 16 pp. 10195-10195 [ DOI: doi:10.1038/s41467-025-65502-8 Pubmed: 41309593 ]

EMD-51044
Download Map
3D View
Group II intron assembly intermediate Domain 1 to 3 Partly open state
CryoEM
Release date: Nov. 5, 2025
Resolution: 4.01 Å
EM Method: Single-particle
Fitted PDBs: 9g4l
Q-score: 0.325
Similar entry percentile: 34%

Jadhav S, Maiorca M, Manigrasso J, Saha S, Rakitch A, Muscat S, Mulvaney T, De Vivo M, Topf M, Marcia M

Nat Commun (2025) 16 pp. 10195-10195 [ DOI: doi:10.1038/s41467-025-65502-8 Pubmed: 41309593 ]

EMD-51068
Download Map
3D View
Group II intron assembly intermediate Domain 1 and 2 Fully open state
CryoEM
Release date: Nov. 5, 2025
Resolution: 4.69 Å
EM Method: Single-particle
Fitted PDBs: 9g4v
Q-score: 0.264
Similar entry percentile: 48%

Jadhav S, Maiorca M, Manigrasso J, Saha S, Rakitch A, Muscat S, Mulvaney T, De Vivo M, Topf M, Marcia M

Nat Commun (2025) 16 pp. 10195-10195 [ DOI: doi:10.1038/s41467-025-65502-8 Pubmed: 41309593 ]

EMD-51077
Download Map
3D View
Group II intron assembly intermediate Domain 1, 2, 3 and 4 Partly open state
CryoEM
Release date: Nov. 5, 2025
Resolution: 6.3 Å
EM Method: Single-particle
Fitted PDBs: 9g54
Q-score: 0.161
Similar entry percentile: 46%

Jadhav S, Maiorca M, Manigrasso J, Saha S, Rakitch A, Muscat S, Mulvaney T, De Vivo M, Topf M, Marcia M

Nat Commun (2025) 16 pp. 10195-10195 [ DOI: doi:10.1038/s41467-025-65502-8 Pubmed: 41309593 ]

EMD-52863
Download Map
3D View
HSV-2 postfusion glycoprotein B
CryoEM
Release date: Sept. 3, 2025
Resolution: 2.21 Å
EM Method: Single-particle
Fitted PDBs: 9ih8
Q-score: 0.639
Similar entry percentile: 73%

Vollmer B, Ebel H, Rees R, Nentwig J, Mulvaney T, Schunemann J, Krull J, Topf M, Gorlich D, Grunewald K

Nature (2025) 646 pp. 433-441 [ DOI: doi:10.1038/s41586-025-09438-5 Pubmed: 40903574 ]

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Showing 1 - 10 of 77. Page 1 of 8
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Filter By

Current Database

  • EMDB [77]

Current status

  • REL [77]

Sample type

  • Protein [63]
  • Complex [41]
  • Sample [34]
  • Ligand [28]
  • RNA [8]
  • Virus [7]

Organism

  • Homo sapiens [25]
  • Bos taurus [19]
  • Escherichia coli [12]
  • Synthetic construct [7]
  • Sus scrofa [7]
  • Mus musculus [6]
  • Oceanobacillus iheyensis [6]
  • Human herpesvirus 1 [4]
  • Pleurotus ostreatus [4]
  • Bacillus phage spp1 [3]
  • Saccharomyces cerevisiae [3]
  • Oryctolagus cuniculus [3]
  • Human herpesvirus 1 [2]
  • Simplexvirus humanalpha2 [2]
  • Streptococcus suis [2]
  • Vicugna pacos [2]
  • Enterovirus a [2]
  • Pseudomonas monteilii [2]
  • Plasmodium falciparum [1]
  • Plasmodium falciparum [1]
  • Drosophila melanogaster [1]
  • Canis lupus [1]

EM Method

  • Single-particle [66]
  • Helical reconstruction [7]
  • Subtomogram averaging [4]

Resolution

  • ≥ 2Å and < 3Å [7]
  • ≥ 3Å and < 4Å [6]
  • ≥ 4Å and < 5Å [18]
  • ≥ 5Å and < 6Å [7]
  • ≥ 6Å and < 8Å [15]
  • ≥ 8Å and < 12Å [14]
  • ≥ 12Å and < 16Å [6]
  • ≥ 16Å and < 20Å [1]
  • ≥ 20Å and < 30Å [2]
  • ≥ 30Å [1]

Model molecular weight

  • 50-100 kDa [8]
  • 100-250 kDa [29]
  • 250-500 kDa [5]
  • 500-1000 kDa [8]
  • 1-2 MDa [7]
  • 2-5 MDa [3]
  • > 10 MDa [3]

Release Date

  • 2026 [3]
  • 2025 [10]
  • 2023 [2]
  • 2022 [1]
  • 2021 [2]
  • 2020 [3]
  • 2019 [3]
  • 2018 [7]
  • 2017 [12]
  • 2016 [3]
  • 2015 [6]
  • 2014 [7]
  • 2013 [2]
  • 2012 [9]
  • 2011 [2]
  • 2010 [3]
  • 2009 [2]

Author by name

  • Topf M [77]
  • Moores CA [21]
  • Saibil HR [20]
  • Atherton J [19]
  • Joseph AP [15]
  • Farabella I [13]
  • Mulvaney T [13]
  • Clare DK [11]
  • Houdusse A [11]
  • Rosenfeld SS [11]
  • Yu IM [11]
  • Lukoyanova N [9]
  • Vasishtan D [9]
  • Grunewald K [8]
  • Boyd CM [7]
  • Brooks NJ [7]
  • Bubeck D [7]
  • Farr GW [7]
  • Gardner S [7]
  • Horwich AL [7]
  • Menny A [7]
  • Moores C [7]
  • Morgan BP [7]
  • Pandurangan AP [7]
  • Quispe J [7]
  • Serna M [7]
  • Stagg S [7]
  • De Vivo M [6]
  • Dunstone MA [6]
  • Jadhav S [6]
  • Jadhav SS [6]
  • Maiorca M [6]
  • Manigrasso J [6]
  • Marcia M [6]
  • Muscat S [6]
  • Rakitch A [6]
  • Reboul CF [6]
  • Saha S [6]
  • Vollmer B [6]
  • Boyd CB [5]
  • Gardener S [5]
  • Mielke T [5]
  • Pena A [5]
  • Roberts AJ [5]
  • Trapani JA [5]
  • Voskoboinik I [5]
  • Caradoc-davies TT [4]
  • Clause J [4]
  • Cook A [4]
  • Cook AD [4]
  • Ebel H [4]
  • Ekkel S [4]
  • Ekkel SM [4]
  • Gorlich D [4]
  • Gruenewald K [4]
  • Hatfaludi T [4]
  • Hotze EM [4]
  • Joseph A [4]
  • Kleifeld O [4]
  • Kondos SC [4]
  • Krull J [4]
  • Law RH [4]
  • Law RHP [4]
  • Major J [4]
  • Muretta JM [4]
  • Nentwig J [4]
  • Oliver K [4]
  • Perugini M [4]
  • Rees R [4]
  • Schunemann J [4]
  • Sourigues Y [4]
  • Spicer BA [4]
  • Traore DA [4]
  • Tweten RK [4]
  • Whisstock JC [4]
  • Abis G [3]
  • Akey CW [3]
  • Akhmanova A [3]
  • Baldus M [3]
  • Brasiles S [3]
  • Burger J [3]
  • Chu LY [3]
  • Conte MR [3]
  • El Sadek Fadel M [3]
  • Eswar N [3]
  • Gordon-weeks PR [3]
  • Grant BJ [3]
  • Houben K [3]
  • Hua S [3]
  • Ignatiou A [3]
  • Jiang K [3]
  • Locke J [3]
  • Luo Y [3]
  • Malhotra S [3]
  • Mayer TU [3]
  • Mockel MM [3]
  • Nagar N [3]
  • Oozeer F [3]
  • Orlova EV [3]
  • Scarabelli G [3]

Author by ORCID

  • Topf M [14]
  • Mulvaney T [9]
  • Muscat S [6]
  • Marcia M [6]
  • De Vivo M [6]
  • Manigrasso J [6]
  • Saha S [6]
  • Conte MR [3]
  • Mielke T [3]
  • Saibil HR [3]
  • Gordon-weeks PR [3]
  • Atherton J [3]
  • Oozeer F [3]
  • Abis G [3]
  • Orlova EV [3]
  • Zhao W [3]
  • Bubeck D [2]
  • Zhao JZ [2]
  • Sethi A [2]
  • Brooks NJ [2]
  • Nelson ME [2]
  • Kassa A [2]
  • Leininger C [2]
  • Eswar N [2]
  • Lukoyanova N [1]
  • Malhotra S [1]
  • Voskoboinik I [1]
  • Trapani JA [1]

Journal

  • NAT COMMUN [21]
  • ELIFE [13]
  • CELL [7]
  • STRUCTURE [7]
  • NAT STRUCT MOL BIOL [4]
  • NATURE [4]
  • PLOS BIOL [4]
  • PNAS [4]
  • SCI ADV [4]
  • J BIOL CHEM [3]
  • EMBO REP [2]
  • J VIROL [2]
  • METHODS [2]
  • TO BE PUBLISHED [1]

Software

  • RELION [14]
  • CRYOSPARC [11]
  • CTFFIND [10]
  • SPIDER [8]
  • CHIMERA [7]
  • CHIMERA, FLEX-EM [7]
  • SPIDER, FREALIGN [7]
  • SPIDER, IMAGIC [7]
  • CHIMERA, FLEX-EM, NAMD2.6 [6]
  • FREALIGN [6]
  • FLEX-EM [4]
  • IMAGIC, SPIDER [4]
  • CHIMERA, FLEX-EM, MODELLER, TEMPY [3]
  • IMAGIC [3]
  • AUTO3DEM [2]
  • EMAN [2]
  • IMAGIC-5, SPIDER [2]
  • JSUBTOMO [2]
  • RELION, CTFFIND3 [2]
  • SPIDER, IMAGIC, EMAN [2]
  • 3DMOD [1]
  • CHIMERA, FLEX-EM, ADP-EM, GMFIT, TEMPY [1]
  • CHIMERA, FLEX-EM, MODELLER [1]
  • EMAN2 [1]
  • IMOD, PEET [1]
  • MOD-EM AND FLEX-EM [1]
  • PEET [1]
  • SITUS [1]

Microscope

  • FEI POLARA 300 [32]
  • FEI TITAN KRIOS [19]
  • FEI TECNAI F20 [15]
  • TFS KRIOS [9]
  • FEI TECNAI 20 [1]
  • FEI TECNAI F30 [1]

Electron Source

  • FIELD EMISSION GUN [77]

Film or detector model

  • GATAN ULTRASCAN 4000 4K X 4K [22]
  • GATAN K2 SUMMIT 4K X 4K [17]
  • FEI FALCON II 4K X 4K [7]
  • DIRECT ELECTRON DE-20 5K X 3K [6]
  • KODAK SO-163 FILM [6]
  • GATAN K3 BIOQUANTUM 6K X 4K [5]
  • GATAN K2 QUANTUM 4K X 4K [4]
  • GATAN K2 BASE 4K X 4K [2]
  • GATAN K3 6K X 4K [2]
  • GENERIC GATAN 4K X 4K [2]
  • TFS FALCON 4I 4K X 4K [2]
  • FEI FALCON IV 4K X 4K [1]
  • GENERIC TVIPS 4K X 4K [1]

External links

  • PDB [63]
  • UniProt [52]
  • PDBe-Kb [43]
  • AlphaFold DB [39]
  • InterPro [31]
  • Gene Ontology [29]
  • Pfam [23]
  • ChEBI [22]
  • ChEMBL [20]
  • DrugBank [20]
  • Complex Portal [6]
  • SCOP2 [2]