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author:"Stierli F"

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Current Database

  • EMDB [4]

Current status

  • REL [4]

Sample type

  • Complex [4]
  • Protein [4]
  • Ligand [1]

Organism

  • Mus musculus [4]
  • Synthetic construct [3]

EM Method

  • Single-particle [4]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 250-500 kDa [1]
  • 500-1000 kDa [3]

Release Date

  • 2026 [4]

Author by name

  • Deneka D [4]
  • Dutzler R [4]
  • Lehmann EF [4]
  • Rutz S [4]
  • Stierli F [4]

Author by ORCID

  • Dutzler R [4]
  • Lehmann EF [4]
  • Rutz S [4]

Journal

  • NAT COMMUN [4]

Software

  • CRYOSPARC [4]

Microscope

  • TFS KRIOS [3]
  • TFS GLACIOS [1]

Electron Source

  • FIELD EMISSION GUN [4]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [3]
  • TFS FALCON 4I 4K X 4K [1]

External links

  • AlphaFold DB [4]
  • PDB [4]
  • PDBe-Kb [4]
  • Pfam [4]
  • UniProt [4]
  • ChEBI [1]
  • ChEMBL [1]
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EMD-55589
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3D View
Structure of mouse full-length LRRC8D
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 9t5m
Q-score: 0.35
Similar entry percentile: 7%

Lehmann EF, Stierli F, Rutz S, Deneka D, Dutzler R

Nat Commun (2026) 17 [ Pubmed: 42754598 DOI: doi:10.1038/s41467-026-77508-x ]

EMD-55590
Download Map
3D View
Structure of heteromeric mouse LRRC8A/D Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1, Conformation 1
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 9t5n
Q-score: 0.313
Similar entry percentile: 4%

Lehmann EF, Stierli F, Rutz S, Deneka D, Dutzler R

Nat Commun (2026) 17 [ Pubmed: 42754598 DOI: doi:10.1038/s41467-026-77508-x ]

EMD-55591
Download Map
3D View
Structure of heteromeric mouse LRRC8A/D Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1, Conformation 2
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 9t5o
Q-score: 0.249
Similar entry percentile: 2%

Lehmann EF, Stierli F, Rutz S, Deneka D, Dutzler R

Nat Commun (2026) 17 [ Pubmed: 42754598 DOI: doi:10.1038/s41467-026-77508-x ]

EMD-55592
Download Map
3D View
Structure of heteromeric mouse LRRC8A/D Volume-Regulated Anion Channel in complex with synthetic nanobody Sb4
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.97 Å
EM Method: Single-particle
Fitted PDBs: 9t5p
Q-score: 0.302
Similar entry percentile: 22%

Lehmann EF, Stierli F, Rutz S, Deneka D, Dutzler R

Nat Commun (2026) 17 [ Pubmed: 42754598 DOI: doi:10.1038/s41467-026-77508-x ]

Sort by: Download
Showing 1 - 4 of 4. Page 1 of 1
Display:
Statistics
×

Download


Preview 10 entries View All Download file

Filter By

Current Database

  • EMDB [4]

Current status

  • REL [4]

Sample type

  • Complex [4]
  • Protein [4]
  • Ligand [1]

Organism

  • Mus musculus [4]
  • Synthetic construct [3]

EM Method

  • Single-particle [4]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 250-500 kDa [1]
  • 500-1000 kDa [3]

Release Date

  • 2026 [4]

Author by name

  • Deneka D [4]
  • Dutzler R [4]
  • Lehmann EF [4]
  • Rutz S [4]
  • Stierli F [4]

Author by ORCID

  • Dutzler R [4]
  • Lehmann EF [4]
  • Rutz S [4]

Journal

  • NAT COMMUN [4]

Software

  • CRYOSPARC [4]

Microscope

  • TFS KRIOS [3]
  • TFS GLACIOS [1]

Electron Source

  • FIELD EMISSION GUN [4]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [3]
  • TFS FALCON 4I 4K X 4K [1]

External links

  • AlphaFold DB [4]
  • PDB [4]
  • PDBe-Kb [4]
  • Pfam [4]
  • UniProt [4]
  • ChEBI [1]
  • ChEMBL [1]