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author:"Shafi T"

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Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Protein [6]
  • Ligand [3]

Organism

  • Mus musculus [3]
  • Drosophila melanogaster [3]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 3Å and < 4Å [1]
  • ≥ 4Å and < 5Å [2]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [2]

Model molecular weight

  • 100-250 kDa [3]
  • 250-500 kDa [3]

Release Date

  • 2026 [2]
  • 2023 [1]
  • 2021 [2]
  • 2018 [1]

Author by name

  • Shafi T [6]
  • Barbieri A [3]
  • Brzozowski AM [3]
  • Collins RF [3]
  • Ford RC [3]
  • Jenkins HT [3]
  • Thonghin N [3]
  • Chechik M [2]
  • Isupov MN [2]
  • Moroz OV [2]
  • Prince SM [2]
  • De Meyts P [1]
  • Frittmann O [1]
  • Siebert A [1]
  • Viola CM [1]

Author by ORCID

  • Brzozowski AM [3]
  • Jenkins HT [3]
  • Isupov MN [2]
  • Shafi T [2]
  • Moroz OV [2]
  • De Meyts P [1]
  • Ford RC [1]

Journal

  • MEMBRANES (BASEL) [2]
  • TO BE PUBLISHED [2]
  • BMC STRUCT BIOL [1]
  • NAT COMMUN [1]

Software

  • CISTEM [2]

Microscope

  • FEI TITAN KRIOS [4]
  • TFS GLACIOS [2]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [3]
  • FEI FALCON IV 4K X 4K [2]
  • GATAN K3 6K X 4K [1]

External links

  • AlphaFold DB [6]
  • PDB [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • Gene Ontology [4]
  • InterPro [4]
  • ChEBI [3]
  • ChEMBL [3]
  • EMPIAR [2]
  • DrugBank [1]
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EMD-52236
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Raw data
EMPIAR-13076
Drosophila melanogaster insulin receptor ectodomain in complex with one DILP2 molecule
CryoEM
Release date: May 6, 2026
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 9hkt
Q-score: 0.299

Shafi T, Moroz OV, Jenkins HT, Chechik M, Isupov MN, Brzozowski AM

To Be Published

EMD-52310
Download Map
3D View
Raw data
EMPIAR-13076
Drosophila melanogaster insulin receptor ectodomain in complex with two DILP2 molecules
CryoEM
Release date: May 6, 2026
Resolution: 6.25 Å
EM Method: Single-particle
Fitted PDBs: 9hni
Q-score: 0.244

Shafi T, Moroz OV, Jenkins HT, Chechik M, Isupov MN, Brzozowski AM

To Be Published

EMD-16718
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Drosophila melanogaster insulin receptor ectodomain in complex with DILP5
CryoEM
Release date: Dec. 20, 2023
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8cls
Q-score: 0.441

Viola CM, Frittmann O, Jenkins HT, Shafi T, De Meyts P, Brzozowski AM

Nat Commun (2023) 14 pp. 6271-6271 [ Pubmed: 37805602 DOI: doi:10.1038/s41467-023-41862-x ]

EMD-13059
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Structure of ABCB1/P-glycoprotein in the presence of the CFTR potentiator ivacaftor
CryoEM
Release date: Dec. 8, 2021
Resolution: 5.4 Å
EM Method: Single-particle
Fitted PDBs: 7otg
Q-score: 0.091

Barbieri A, Thonghin N, Shafi T, Prince SM, Collins RF, Ford RC

Membranes (Basel) (2021) 11 [ Pubmed: 34940424 DOI: doi:10.3390/membranes11120923 ]

EMD-13060
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Structure of ABCB1/P-glycoprotein in apo state
CryoEM
Release date: Dec. 8, 2021
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7oti
Q-score: 0.066

Barbieri A, Thonghin N, Shafi T, Prince SM, Collins RF, Ford RC

Membranes (Basel) (2021) 11 [ Pubmed: 34940424 DOI: doi:10.3390/membranes11120923 ]

EMD-4391
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Structure of P-glycoprotein ABCB1 in the post-hydrolytic state
CryoEM
Release date: May 23, 2018
Resolution: 7.9 Å
EM Method: Single-particle
Fitted PDBs: 6gdi
Q-score: 0.141

Thonghin N, Collins RF, Barbieri A, Shafi T, Siebert A, Ford RC

BMC Struct Biol (2018) 18 pp. 17-17 [ Pubmed: 30545335 DOI: doi:10.1186/s12900-018-0098-z ]

Sort by: Download
Showing 1 - 6 of 6. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Protein [6]
  • Ligand [3]

Organism

  • Mus musculus [3]
  • Drosophila melanogaster [3]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 3Å and < 4Å [1]
  • ≥ 4Å and < 5Å [2]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [2]

Model molecular weight

  • 100-250 kDa [3]
  • 250-500 kDa [3]

Release Date

  • 2026 [2]
  • 2023 [1]
  • 2021 [2]
  • 2018 [1]

Author by name

  • Shafi T [6]
  • Barbieri A [3]
  • Brzozowski AM [3]
  • Collins RF [3]
  • Ford RC [3]
  • Jenkins HT [3]
  • Thonghin N [3]
  • Chechik M [2]
  • Isupov MN [2]
  • Moroz OV [2]
  • Prince SM [2]
  • De Meyts P [1]
  • Frittmann O [1]
  • Siebert A [1]
  • Viola CM [1]

Author by ORCID

  • Brzozowski AM [3]
  • Jenkins HT [3]
  • Isupov MN [2]
  • Shafi T [2]
  • Moroz OV [2]
  • De Meyts P [1]
  • Ford RC [1]

Journal

  • MEMBRANES (BASEL) [2]
  • TO BE PUBLISHED [2]
  • BMC STRUCT BIOL [1]
  • NAT COMMUN [1]

Software

  • CISTEM [2]

Microscope

  • FEI TITAN KRIOS [4]
  • TFS GLACIOS [2]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [3]
  • FEI FALCON IV 4K X 4K [2]
  • GATAN K3 6K X 4K [1]

External links

  • AlphaFold DB [6]
  • PDB [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • Gene Ontology [4]
  • InterPro [4]
  • ChEBI [3]
  • ChEMBL [3]
  • EMPIAR [2]
  • DrugBank [1]