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author:"Rutz S"

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Current Database

  • EMDB [28]

Current status

  • REL [28]

Sample type

  • Complex [27]
  • Protein [20]
  • Ligand [3]
  • Cellular component [1]

Organism

  • Mus musculus [18]
  • Synthetic construct [11]
  • Homo sapiens [11]
  • Human mastadenovirus c [1]
  • Aequorea victoria [1]
  • Oryctolagus cuniculus [1]

EM Method

  • Single-particle [28]

Resolution

  • ≥ 2Å and < 3Å [6]
  • ≥ 3Å and < 4Å [12]
  • ≥ 4Å and < 5Å [3]
  • ≥ 6Å and < 8Å [5]
  • ≥ 8Å and < 12Å [1]
  • ≥ 16Å and < 20Å [1]

Release Date

  • 2026 [4]
  • 2024 [5]
  • 2023 [5]
  • 2022 [8]
  • 2021 [6]

Author by name

  • Rutz S [28]
  • Dutzler R [23]
  • Deneka D [17]
  • Sawicka M [13]
  • Lehmann EF [9]
  • Dittmann A [7]
  • Hutter CAJ [6]
  • Seeger MA [6]
  • Arenzana TL [5]
  • Azumaya C [5]
  • Barone A [5]
  • Campos-xavier B [5]
  • Chiu C [5]
  • Comps-agrar L [5]
  • Garavelli L [5]
  • Ho H [5]
  • Innes AM [5]
  • Janezic E [5]
  • Johnson M [5]
  • Joshi P [5]
  • Kellenberger S [5]
  • Koerber JT [5]
  • Masureel M [5]
  • Nicoludis JM [5]
  • Noreng S [5]
  • Payandeh J [5]
  • Peng Z [5]
  • Peter V [5]
  • Quinodoz M [5]
  • Rivolta C [5]
  • Seki A [5]
  • Shi Y [5]
  • Sun D [5]
  • Sun Y [5]
  • Superti-furga A [5]
  • Tam C [5]
  • Unger S [5]
  • Wang B [5]
  • Wang J [5]
  • Zhou T [5]
  • Innes MA [4]
  • Stierli F [4]
  • Innes M [1]
  • Lam AKM [1]

Journal

  • NAT COMMUN [16]
  • NAT STRUCT MOL BIOL [7]
  • EMBO J [5]

Software

  • CRYOSPARC [4]

Microscope

  • FEI TITAN KRIOS [18]
  • TFS KRIOS [8]
  • FEI POLARA 300 [1]
  • TFS GLACIOS [1]

Electron Source

  • FIELD EMISSION GUN [28]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [21]
  • FEI FALCON IV 4K X 4K [4]
  • FEI FALCON III 4K X 4K [1]
  • GATAN K2 SUMMIT 4K X 4K [1]
  • TFS FALCON 4I 4K X 4K [1]

External links

  • AlphaFold DB [16]
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Showing 1 - 10 of 28. Page 1 of 3
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EMD-55589
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3D View
Structure of mouse full-length LRRC8D
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 9t5m
Q-score: 0.35
Similar entry percentile: 7%

Lehmann EF, Stierli F, Rutz S, Deneka D, Dutzler R

Nat Commun (2026) 17 [ Pubmed: 42754598 DOI: doi:10.1038/s41467-026-77508-x ]

EMD-55590
Download Map
3D View
Structure of heteromeric mouse LRRC8A/D Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1, Conformation 1
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 9t5n
Q-score: 0.313
Similar entry percentile: 4%

Lehmann EF, Stierli F, Rutz S, Deneka D, Dutzler R

Nat Commun (2026) 17 [ Pubmed: 42754598 DOI: doi:10.1038/s41467-026-77508-x ]

EMD-55591
Download Map
3D View
Structure of heteromeric mouse LRRC8A/D Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1, Conformation 2
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 9t5o
Q-score: 0.249
Similar entry percentile: 2%

Lehmann EF, Stierli F, Rutz S, Deneka D, Dutzler R

Nat Commun (2026) 17 [ Pubmed: 42754598 DOI: doi:10.1038/s41467-026-77508-x ]

EMD-55592
Download Map
3D View
Structure of heteromeric mouse LRRC8A/D Volume-Regulated Anion Channel in complex with synthetic nanobody Sb4
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.97 Å
EM Method: Single-particle
Fitted PDBs: 9t5p
Q-score: 0.302
Similar entry percentile: 22%

Lehmann EF, Stierli F, Rutz S, Deneka D, Dutzler R

Nat Commun (2026) 17 [ Pubmed: 42754598 DOI: doi:10.1038/s41467-026-77508-x ]

EMD-19495
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3D View
Structure of a homomeric human LRRC8C Volume-Regulated Anion Channel
CryoEM
Release date: Nov. 13, 2024
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 8rts
Q-score: 0.225
Similar entry percentile: 5%

Quinodoz M, Rutz S, Peter V, Garavelli L, Innes AM, Lehmann EF, Kellenberger S, Peng Z, Barone A, Campos-Xavier B, Unger S, Rivolta C, Dutzler R, Superti-Furga A

EMBO J (2025) 44 pp. 413-436 [ Pubmed: 39623139 DOI: doi:10.1038/s44318-024-00322-y ]

EMD-50072
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3D View
Structure of the extracellular subdomain of a homomeric LRRC8C truncation disease mutant
CryoEM
Release date: Nov. 13, 2024
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 9ezc
Q-score: 0.297
Similar entry percentile: 7%

Quinodoz M, Rutz S, Peter V, Garavelli L, Innes AM, Lehmann EF, Kellenberger S, Peng Z, Barone A, Campos-Xavier B, Unger S, Rivolta C, Dutzler R, Superti-Furga A

EMBO J (2025) 44 pp. 413-436 [ Pubmed: 39623139 DOI: doi:10.1038/s44318-024-00322-y ]

EMD-50073
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3D View
Cryo-EM structure of a homomeric LRRC8C truncation disease mutant, with C1 symmetry
CryoEM
Release date: Nov. 13, 2024
Resolution: 7.32 Å
EM Method: Single-particle

Quinodoz M, Rutz S, Peter V, Garavelli L, Innes AM, Lehmann EF, Kellenberger S, Peng Z, Barone A, Campos-Xavier B, Unger S, Rivolta C, Dutzler R, Superti-Furga A

EMBO J (2025) 44 pp. 413-436 [ Pubmed: 39623139 DOI: doi:10.1038/s44318-024-00322-y ]

EMD-50074
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3D View
Cryo-EM structure of a homomeric LRRC8C truncation disease mutant, with C7 symmetry
CryoEM
Release date: Nov. 13, 2024
Resolution: 4.95 Å
EM Method: Single-particle

Quinodoz M, Rutz S, Peter V, Garavelli L, Innes AM, Lehmann EF, Kellenberger S, Peng Z, Barone A, Campos-Xavier B, Unger S, Rivolta C, Dutzler R, Superti-Furga A

EMBO J (2025) 44 pp. 413-436 [ Pubmed: 39623139 DOI: doi:10.1038/s44318-024-00322-y ]

EMD-50123
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3D View
Structure of a homomeric LRRC8C point mutation disease mutant
CryoEM
Release date: Nov. 13, 2024
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 9f16
Q-score: 0.251
Similar entry percentile: 31%

Quinodoz M, Rutz S, Peter V, Garavelli L, Innes AM, Lehmann EF, Kellenberger S, Peng Z, Barone A, Campos-Xavier B, Unger S, Rivolta C, Dutzler R, Superti-Furga A

EMBO J (2025) 44 pp. 413-436 [ Pubmed: 39623139 DOI: doi:10.1038/s44318-024-00322-y ]

EMD-41370
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3D View
Structure of a class A GPCR/Fab complex
CryoEM
Release date: Dec. 20, 2023
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8tlm

Sun D, Sun Y, Janezic E, Zhou T, Johnson M, Azumaya C, Noreng S, Chiu C, Seki A, Arenzana TL, Nicoludis JM, Shi Y, Wang B, Ho H, Joshi P, Tam C, Payandeh J, Comps-Agrar L, Wang J, Rutz S, Koerber JT, Masureel M

Nat Commun (2023) 14 pp. 7940-7940 [ DOI: doi:10.1038/s41467-023-43601-8 Pubmed: 38040762 ]

Sort by: Download
Showing 1 - 10 of 28. Page 1 of 3
Display:
Statistics
×

Download


Preview 10 entries View All Download file

Filter By

Current Database

  • EMDB [28]

Current status

  • REL [28]

Sample type

  • Complex [27]
  • Protein [20]
  • Ligand [3]
  • Cellular component [1]

Organism

  • Mus musculus [18]
  • Synthetic construct [11]
  • Homo sapiens [11]
  • Human mastadenovirus c [1]
  • Aequorea victoria [1]
  • Oryctolagus cuniculus [1]

EM Method

  • Single-particle [28]

Resolution

  • ≥ 2Å and < 3Å [6]
  • ≥ 3Å and < 4Å [12]
  • ≥ 4Å and < 5Å [3]
  • ≥ 6Å and < 8Å [5]
  • ≥ 8Å and < 12Å [1]
  • ≥ 16Å and < 20Å [1]

Release Date

  • 2026 [4]
  • 2024 [5]
  • 2023 [5]
  • 2022 [8]
  • 2021 [6]

Author by name

  • Rutz S [28]
  • Dutzler R [23]
  • Deneka D [17]
  • Sawicka M [13]
  • Lehmann EF [9]
  • Dittmann A [7]
  • Hutter CAJ [6]
  • Seeger MA [6]
  • Arenzana TL [5]
  • Azumaya C [5]
  • Barone A [5]
  • Campos-xavier B [5]
  • Chiu C [5]
  • Comps-agrar L [5]
  • Garavelli L [5]
  • Ho H [5]
  • Innes AM [5]
  • Janezic E [5]
  • Johnson M [5]
  • Joshi P [5]
  • Kellenberger S [5]
  • Koerber JT [5]
  • Masureel M [5]
  • Nicoludis JM [5]
  • Noreng S [5]
  • Payandeh J [5]
  • Peng Z [5]
  • Peter V [5]
  • Quinodoz M [5]
  • Rivolta C [5]
  • Seki A [5]
  • Shi Y [5]
  • Sun D [5]
  • Sun Y [5]
  • Superti-furga A [5]
  • Tam C [5]
  • Unger S [5]
  • Wang B [5]
  • Wang J [5]
  • Zhou T [5]
  • Innes MA [4]
  • Stierli F [4]
  • Innes M [1]
  • Lam AKM [1]

Journal

  • NAT COMMUN [16]
  • NAT STRUCT MOL BIOL [7]
  • EMBO J [5]

Software

  • CRYOSPARC [4]

Microscope

  • FEI TITAN KRIOS [18]
  • TFS KRIOS [8]
  • FEI POLARA 300 [1]
  • TFS GLACIOS [1]

Electron Source

  • FIELD EMISSION GUN [28]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [21]
  • FEI FALCON IV 4K X 4K [4]
  • FEI FALCON III 4K X 4K [1]
  • GATAN K2 SUMMIT 4K X 4K [1]
  • TFS FALCON 4I 4K X 4K [1]

External links

  • AlphaFold DB [16]