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author:"Roesler C"

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Current Database

  • EMDB [7]

Current status

  • REL [7]

Sample type

  • Complex [7]
  • Protein [7]
  • RNA [6]
  • Ligand [2]

Organism

  • Human respiratory syncytial virus [6]
  • Human respiratory syncytial virus [1]

EM Method

  • Single-particle [7]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [6]

Model molecular weight

  • 250-500 kDa [7]

Release Date

  • 2026 [4]
  • 2023 [2]
  • 2020 [1]

Author by name

  • Cao D [7]
  • Gao Y [7]
  • Liang B [7]
  • Roesler C [7]
  • Chen Z [6]
  • Gooneratne I [6]
  • Mera C [6]
  • Slack J [5]
  • Zhuang L [5]
  • Berry J [4]
  • Nudell-cook E [4]
  • Royal M [4]
  • Shaik M [4]
  • Vy J [4]
  • Youngs R [4]
  • Antonova A [3]
  • D Cunha P [3]
  • Rice S [3]
  • Romanelli S [3]
  • Katta D [2]
  • Lemons W [2]
  • Ramanathan A [2]
  • Wang Q [2]
  • Domke M [1]
  • Forero G [1]
  • Juneja P [1]
  • Keating S [1]

Author by ORCID

  • Gao Y [7]
  • Cao D [7]
  • Liang B [7]
  • Gooneratne I [6]
  • Chen Z [4]
  • Katta D [2]
  • Slack J [1]
  • Roesler C [1]
  • Juneja P [1]

Journal

  • NAT COMMUN [5]
  • NATURE [2]

Software

  • COOT [4]
  • PHENIX [1]
  • UCSF CHIMERAX [1]

Microscope

  • TFS KRIOS [4]
  • FEI TITAN KRIOS [2]
  • FEI TALOS ARCTICA [1]

Electron Source

  • FIELD EMISSION GUN [7]

Film or detector model

  • GATAN K3 6K X 4K [6]
  • GATAN K2 SUMMIT 4K X 4K [1]

External links

  • PDB [7]
  • UniProt [7]
  • PDBe-Kb [6]
  • ChEBI [2]
  • DrugBank [2]
  • Gene Ontology [2]
  • InterPro [2]
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EMD-71611
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3D View
Cryo-EM structure of the respiratory syncytial virus polymerase L:P in NTP-bound elongation state
CryoEM
Release date: May 6, 2026
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 9pfr
Q-score: 0.519

Cao D, Chen Z, Gao Y, Roesler C, Gooneratne I, Mera C, Zhuang L, Slack J, Nudell-Cook E, Vy J, Berry J, Royal M, Shaik M, Youngs R, Liang B

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72519-0 Pubmed: 42049741 ]

EMD-71612
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Cryo-EM structure of the respiratory syncytial virus polymerase L:P in pre-reaction elongation state
CryoEM
Release date: May 6, 2026
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 9pfs
Q-score: 0.562

Cao D, Chen Z, Gao Y, Roesler C, Gooneratne I, Mera C, Zhuang L, Slack J, Nudell-Cook E, Vy J, Berry J, Royal M, Shaik M, Youngs R, Liang B

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72519-0 Pubmed: 42049741 ]

EMD-71613
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Cryo-EM structure of the respiratory syncytial virus polymerase L:P in pre-translocation elongation state
CryoEM
Release date: May 6, 2026
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 9pft
Q-score: 0.545

Cao D, Chen Z, Gao Y, Roesler C, Gooneratne I, Mera C, Zhuang L, Slack J, Nudell-Cook E, Vy J, Berry J, Royal M, Shaik M, Youngs R, Liang B

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72519-0 Pubmed: 42049741 ]

EMD-71614
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Cryo-EM structure of the respiratory syncytial virus polymerase L:P in post-translocation elongation state
CryoEM
Release date: May 6, 2026
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 9pfu
Q-score: 0.45

Cao D, Chen Z, Gao Y, Roesler C, Gooneratne I, Mera C, Zhuang L, Slack J, Nudell-Cook E, Vy J, Berry J, Royal M, Shaik M, Youngs R, Liang B

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72519-0 Pubmed: 42049741 ]

EMD-40641
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Cryo-EM structure of the respiratory syncytial virus polymerase L:P bound to the leader promoter
CryoEM
Release date: Dec. 20, 2023
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8snx
Q-score: 0.523

Cao D, Gao Y, Chen Z, Gooneratne I, Roesler C, Mera C, D'Cunha P, Antonova A, Katta D, Romanelli S, Wang Q, Rice S, Lemons W, Ramanathan A, Liang B

Nature (2024) 625 pp. 611-617 [ Pubmed: 38123676 DOI: doi:10.1038/s41586-023-06867-y ]

EMD-40642
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3D View
Cryo-EM structure of the respiratory syncytial virus polymerase L:P bound to the trailer complementary promoter
CryoEM
Release date: Dec. 20, 2023
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8sny
Q-score: 0.483

Cao D, Gao Y, Chen Z, Gooneratne I, Roesler C, Mera C, D'Cunha P, Antonova A, Katta D, Romanelli S, Wang Q, Rice S, Lemons W, Ramanathan A, Liang B

Nature (2024) 625 pp. 611-617 [ Pubmed: 38123676 DOI: doi:10.1038/s41586-023-06867-y ]

EMD-20754
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3D View
Cryo-EM structure of the respiratory syncytial virus RNA polymerase
CryoEM
Release date: Jan. 22, 2020
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 6uen
Q-score: 0.477

Cao D, Gao Y, Roesler C, Rice S, D'Cunha P, Zhuang L, Slack J, Domke M, Antonova A, Romanelli S, Keating S, Forero G, Juneja P, Liang B

Nat Commun (2020) 11 pp. 368-368 [ DOI: doi:10.1038/s41467-019-14246-3 Pubmed: 31953395 ]

Sort by: Download
Showing 1 - 7 of 7. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [7]

Current status

  • REL [7]

Sample type

  • Complex [7]
  • Protein [7]
  • RNA [6]
  • Ligand [2]

Organism

  • Human respiratory syncytial virus [6]
  • Human respiratory syncytial virus [1]

EM Method

  • Single-particle [7]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [6]

Model molecular weight

  • 250-500 kDa [7]

Release Date

  • 2026 [4]
  • 2023 [2]
  • 2020 [1]

Author by name

  • Cao D [7]
  • Gao Y [7]
  • Liang B [7]
  • Roesler C [7]
  • Chen Z [6]
  • Gooneratne I [6]
  • Mera C [6]
  • Slack J [5]
  • Zhuang L [5]
  • Berry J [4]
  • Nudell-cook E [4]
  • Royal M [4]
  • Shaik M [4]
  • Vy J [4]
  • Youngs R [4]
  • Antonova A [3]
  • D Cunha P [3]
  • Rice S [3]
  • Romanelli S [3]
  • Katta D [2]
  • Lemons W [2]
  • Ramanathan A [2]
  • Wang Q [2]
  • Domke M [1]
  • Forero G [1]
  • Juneja P [1]
  • Keating S [1]

Author by ORCID

  • Gao Y [7]
  • Cao D [7]
  • Liang B [7]
  • Gooneratne I [6]
  • Chen Z [4]
  • Katta D [2]
  • Slack J [1]
  • Roesler C [1]
  • Juneja P [1]

Journal

  • NAT COMMUN [5]
  • NATURE [2]

Software

  • COOT [4]
  • PHENIX [1]
  • UCSF CHIMERAX [1]

Microscope

  • TFS KRIOS [4]
  • FEI TITAN KRIOS [2]
  • FEI TALOS ARCTICA [1]

Electron Source

  • FIELD EMISSION GUN [7]

Film or detector model

  • GATAN K3 6K X 4K [6]
  • GATAN K2 SUMMIT 4K X 4K [1]

External links

  • PDB [7]
  • UniProt [7]
  • PDBe-Kb [6]
  • ChEBI [2]
  • DrugBank [2]
  • Gene Ontology [2]
  • InterPro [2]