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author:"Robertson KC"

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Current Database

  • EMDB [15]

Current status

  • REL [15]

Sample type

  • Complex [15]
  • Ligand [3]
  • Protein [3]

Organism

  • Homo sapiens [15]

EM Method

  • Single-particle [15]

Resolution

  • ≥ 3Å and < 4Å [2]
  • ≥ 4Å and < 5Å [8]
  • ≥ 5Å and < 6Å [4]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 250-500 kDa [3]

Release Date

  • 2026 [15]

Author by name

  • Amann SJ [15]
  • Arrowsmith CH [15]
  • Brown NB [15]
  • Brown NG [15]
  • Collins JL [15]
  • Emanuele MJ [15]
  • Funk AV [15]
  • Grishkovskaya I [15]
  • Haselbach D [15]
  • James LI [15]
  • Liu T [15]
  • Mehmood A [15]
  • Miao Y [15]
  • Norris-drouin JL [15]
  • Robertson KC [15]
  • Tabor JR [15]
  • Wang X [15]

Author by ORCID

  • Liu T [15]
  • Amann SJ [15]
  • Haselbach D [15]
  • James LI [15]
  • Brown NG [15]
  • Grishkovskaya I [15]
  • Miao Y [15]
  • Emanuele MJ [15]
  • Funk AV [15]
  • Collins JL [15]

Journal

  • ACTA CRYSTALLOGR D STRUCT BIOL [15]
  • NAT COMMUN [15]

Software

  • CRYOSPARC [15]

Microscope

  • TFS KRIOS [15]

Electron Source

  • FIELD EMISSION GUN [15]

Film or detector model

  • FEI FALCON IV 4K X 4K [15]

External links

  • PDB [15]
  • AlphaFold DB [3]
  • Complex Portal [3]
  • EMPIAR [3]
  • PDBe-Kb [3]
  • Pfam [3]
  • UniProt [3]
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Showing 1 - 10 of 15. Page 1 of 2
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EMD-57178
Download Map
3D View
Raw data
EMPIAR-13495
Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO22 SCF ubiquition ligase in complex with NSD2 via UNC10088
Composite map
CryoEM
Release date: May 6, 2026
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 29hg
Q-score: 0.17

Robertson KC, Amann SJ, Liu T, Funk AV, Wang X, Grishkovskaya I, Mehmood A, Tabor JR, Norris-Drouin JL, Arrowsmith CH, Collins JL, Miao Y, Emanuele MJ, Haselbach D, James LI, Brown NG

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72235-9 Pubmed: 42026065 ]

EMD-57179
Download Map
3D View
Raw data
EMPIAR-13495
Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO22 SCF ubiquition ligase in complex with NSD2, UNC10088 and Bach1
Composite map
CryoEM
Release date: May 6, 2026
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 29hh
Q-score: 0.095

Robertson KC, Amann SJ, Liu T, Funk AV, Wang X, Grishkovskaya I, Mehmood A, Tabor JR, Norris-Drouin JL, Arrowsmith CH, Collins JL, Miao Y, Emanuele MJ, Haselbach D, James LI, Brown NG

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72235-9 Pubmed: 42026065 ]

EMD-57180
Download Map
3D View
Raw data
EMPIAR-13495
Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO22 SCF ubiquition ligase in complex with NSD2 via UNC10415667
Composite map
CryoEM
Release date: May 6, 2026
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 29hi
Q-score: 0.129

Robertson KC, Amann SJ, Liu T, Funk AV, Wang X, Grishkovskaya I, Mehmood A, Tabor JR, Norris-Drouin JL, Arrowsmith CH, Collins JL, Miao Y, Emanuele MJ, Haselbach D, James LI, Brown NG

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72235-9 Pubmed: 42026065 ]

EMD-57298
Download Map
3D View
SKP1-FBXO22-UNC10088-NSD2 locally refined Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO22 SCF ubiquition ligase in complex with NSD2 via UNC10088
Focused map
CryoEM
Release date: May 6, 2026
Resolution: 4.07 Å
EM Method: Single-particle

Robertson KC, Amann SJ, Liu T, Funk AV, Wang X, Grishkovskaya I, Mehmood A, Tabor JR, Norris-Drouin JL, Arrowsmith CH, Collins JL, Miao Y, Emanuele MJ, Haselbach D, James LI, Brown NG

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72235-9 Pubmed: 42026065 ]

EMD-57299
Download Map
3D View
CUL1 locally refined Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO22 SCF ubiquition ligase in complex with NSD2 via UNC10088
CryoEM
Focused map
Release date: May 6, 2026
Resolution: 3.34 Å
EM Method: Single-particle

Robertson KC, Amann SJ, Liu T, Funk AV, Wang X, Grishkovskaya I, Mehmood A, Tabor JR, Norris-Drouin JL, Arrowsmith CH, Collins JL, Miao Y, Emanuele MJ, Haselbach D, James LI, Brown NG

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72235-9 Pubmed: 42026065 ]

EMD-57301
Download Map
3D View
CUL1 C-term, RBX1 locally refined Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO22 SCF ubiquition ligase in complex with NSD2 via UNC10088
CryoEM
Focused map
Release date: May 6, 2026
Resolution: 3.84 Å
EM Method: Single-particle

Robertson KC, Amann SJ, Liu T, Funk AV, Wang X, Grishkovskaya I, Mehmood A, Tabor JR, Norris-Drouin JL, Arrowsmith CH, Collins JL, Miao Y, Emanuele MJ, Haselbach D, James LI, Brown NG

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72235-9 Pubmed: 42026065 ]

EMD-57302
Download Map
3D View
Consensus Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO22 SCF ubiquition ligase in complex with NSD2 via UNC10088
CryoEM
Consensus map
Release date: May 6, 2026
Resolution: 4.08 Å
EM Method: Single-particle

Robertson KC, Amann SJ, Liu T, Funk AV, Wang X, Grishkovskaya I, Mehmood A, Tabor JR, Norris-Drouin JL, Arrowsmith CH, Collins JL, Miao Y, Emanuele MJ, Haselbach D, James LI, Brown NG

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72235-9 Pubmed: 42026065 ]

EMD-57303
Download Map
3D View
SKP1-FBXO22-UNC10088-NSD2 locally refined Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO22 SCF ubiquition ligase in complex with NSD2 via UNC10088 and Bach1
Focused map
CryoEM
Release date: May 6, 2026
Resolution: 4.31 Å
EM Method: Single-particle

Robertson KC, Amann SJ, Liu T, Funk AV, Wang X, Grishkovskaya I, Mehmood A, Tabor JR, Norris-Drouin JL, Arrowsmith CH, Collins JL, Miao Y, Emanuele MJ, Haselbach D, James LI, Brown NG

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72235-9 Pubmed: 42026065 ]

EMD-57304
Download Map
3D View
CUL1-C-terminus-RBX1 locally refined Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO22 SCF ubiquition ligase in complex with NSD2 via UNC10088 and Bach1
Focused map
CryoEM
Release date: May 6, 2026
Resolution: 4.1 Å
EM Method: Single-particle

Robertson KC, Amann SJ, Liu T, Funk AV, Wang X, Grishkovskaya I, Mehmood A, Tabor JR, Norris-Drouin JL, Arrowsmith CH, Collins JL, Miao Y, Emanuele MJ, Haselbach D, James LI, Brown NG

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72235-9 Pubmed: 42026065 ]

EMD-57305
Download Map
3D View
SKP1-CUL1 locally refined Cryo-EM structure of the CUL1-RBX1-SKP1-FBXO22 SCF ubiquition ligase in complex with NSD2 via UNC10088 and Bach1
Focused map
CryoEM
Release date: May 6, 2026
Resolution: 4.5 Å
EM Method: Single-particle

Robertson KC, Amann SJ, Liu T, Funk AV, Wang X, Grishkovskaya I, Mehmood A, Tabor JR, Norris-Drouin JL, Arrowsmith CH, Collins JL, Miao Y, Emanuele MJ, Haselbach D, James LI, Brown NG

Nat Commun (2026) [ DOI: doi:10.1038/s41467-026-72235-9 Pubmed: 42026065 ]

Sort by: Download
Showing 1 - 10 of 15. Page 1 of 2
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [15]

Current status

  • REL [15]

Sample type

  • Complex [15]
  • Ligand [3]
  • Protein [3]

Organism

  • Homo sapiens [15]

EM Method

  • Single-particle [15]

Resolution

  • ≥ 3Å and < 4Å [2]
  • ≥ 4Å and < 5Å [8]
  • ≥ 5Å and < 6Å [4]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 250-500 kDa [3]

Release Date

  • 2026 [15]

Author by name

  • Amann SJ [15]
  • Arrowsmith CH [15]
  • Brown NB [15]
  • Brown NG [15]
  • Collins JL [15]
  • Emanuele MJ [15]
  • Funk AV [15]
  • Grishkovskaya I [15]
  • Haselbach D [15]
  • James LI [15]
  • Liu T [15]
  • Mehmood A [15]
  • Miao Y [15]
  • Norris-drouin JL [15]
  • Robertson KC [15]
  • Tabor JR [15]
  • Wang X [15]

Author by ORCID

  • Liu T [15]
  • Amann SJ [15]
  • Haselbach D [15]
  • James LI [15]
  • Brown NG [15]
  • Grishkovskaya I [15]
  • Miao Y [15]
  • Emanuele MJ [15]
  • Funk AV [15]
  • Collins JL [15]

Journal

  • ACTA CRYSTALLOGR D STRUCT BIOL [15]
  • NAT COMMUN [15]

Software

  • CRYOSPARC [15]

Microscope

  • TFS KRIOS [15]

Electron Source

  • FIELD EMISSION GUN [15]

Film or detector model

  • FEI FALCON IV 4K X 4K [15]

External links

  • PDB [15]
  • AlphaFold DB [3]
  • Complex Portal [3]
  • EMPIAR [3]
  • PDBe-Kb [3]
  • Pfam [3]
  • UniProt [3]