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author:"Omura SN"

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Current Database

  • EMDB [34]

Current status

  • REL [34]

Sample type

  • Complex [34]
  • Protein [26]
  • RNA [26]
  • DNA [24]
  • Ligand [18]
  • Other [1]

Organism

  • Streptococcus pyogenes [12]
  • Staphylococcus aureus [6]
  • Streptococcus pyogenes [5]
  • Murine leukemia virus [4]
  • Mycolicibacterium mucogenicum [4]
  • Lachnospiraceae bacterium nd2006 [3]
  • Acidibacillus sulfuroxidans [3]
  • Bacterium [2]
  • Deinococcus radiodurans [2]
  • Thermanaerosceptrum fracticalcis [1]
  • Dna molecule [1]

EM Method

  • Single-particle [34]

Resolution

  • ≥ 2Å and < 3Å [13]
  • ≥ 3Å and < 4Å [18]
  • ≥ 4Å and < 5Å [2]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [22]
  • 250-500 kDa [4]

Release Date

  • 2026 [5]
  • 2025 [17]
  • 2024 [5]
  • 2023 [7]

Author by name

  • Nureki O [34]
  • Omura SN [34]
  • Hirano H [31]
  • Nakagawa R [26]
  • Itoh Y [25]
  • Shuto Y [14]
  • Zhang F [14]
  • Hoki M [13]
  • Zhu S [13]
  • Hiramoto T [9]
  • Ishiguro S [9]
  • Mori H [9]
  • Ohmori T [9]
  • Onishi K [9]
  • Yachie N [9]
  • Ditommaso T [8]
  • Garrity AJ [8]
  • Hisato H [8]
  • Maben Z [8]
  • Mizuki H [8]
  • Morinaga H [8]
  • Munoz G [8]
  • Ornstein A [8]
  • Satoshi NO [8]
  • Yuzuru I [8]
  • Kise Y [7]
  • Horinaka K [6]
  • Jividen K [6]
  • Kajimoto S [6]
  • Kashiwakura Y [6]
  • Nishimasu H [6]
  • Okazaki S [6]
  • Omura NS [6]
  • Tanaka M [6]
  • Tsai SQ [6]
  • Yamashita K [6]
  • Alfonse LE [5]
  • Cheng DR [5]
  • Hoffman GR [5]
  • Scott DA [5]
  • Yan WX [5]
  • Kusakizako T [4]
  • Wu WY [4]
  • Van Der Oost J [4]
  • Aburatani H [3]
  • Alfonse L [3]
  • Hino T [3]
  • Hoshino A [3]
  • Ishiguro H [3]
  • Kagieva M [3]
  • Karvelis T [3]
  • Kirita Y [3]
  • Kobayashi TA [3]
  • Koonin EV [3]
  • Laffeber C [3]
  • Lebbink HGJ [3]
  • Lebbink JHG [3]
  • Makarova KS [3]
  • Matoba S [3]
  • Motooka D [3]
  • Oost VDJ [3]
  • Ozaki Y [3]
  • Shmakov SA [3]
  • Siksnys V [3]
  • Sudfeld C [3]
  • Takeda NS [3]
  • Takeda SN [3]
  • Tasaka S [3]
  • Togashi T [3]
  • Tokuyama T [3]
  • Uosaki H [3]
  • Villegas Warren R [3]
  • Warren VR [3]
  • Wu YW [3]
  • Yamano H [3]
  • Altae-tran H [1]
  • Dohmae N [1]
  • Kannan S [1]
  • Nakayama H [1]
  • Nety S [1]
  • Ohira T [1]
  • Omura S [1]
  • Osamu N [1]
  • Ryoya N [1]
  • Sakaguchi Y [1]
  • Sano FK [1]
  • Shuto O [1]
  • Suzuki T [1]
  • Tanaka T [1]
  • Yao X [1]
  • Yutaro S [1]

Author by ORCID

  • Nureki O [22]
  • Omura SN [19]
  • Itoh Y [13]
  • Zhang F [8]
  • Shuto Y [8]
  • Ohmori T [6]
  • Tsai SQ [6]
  • Nishimasu H [6]
  • Ishiguro S [6]
  • Yamashita K [6]
  • Kashiwakura Y [6]
  • Hiramoto T [6]
  • Mori H [6]
  • Onishi K [6]
  • Ditommaso T [5]
  • Alfonse LE [5]
  • Van Der Oost J [3]
  • Kusakizako T [3]
  • Lebbink JHG [3]
  • Villegas Warren R [3]

Journal

  • NATURE [14]
  • NAT COMMUN [6]
  • COMMUN BIOL [5]
  • CELL [3]
  • NAT STRUCT MOL BIOL [3]
  • TO BE PUBLISHED [3]

Software

  • CRYOSPARC [3]

Microscope

  • FEI TITAN KRIOS [20]
  • TFS KRIOS [14]

Electron Source

  • FIELD EMISSION GUN [34]

Film or detector model

  • GATAN K3 6K X 4K [25]
  • GATAN K3 BIOQUANTUM 6K X 4K [9]

External links

  • PDB [26]
  • ChEBI [18]
  • DrugBank [18]
  • AlphaFold DB [17]
  • UniProt [17]
  • PDBe-Kb [16]
  • InterPro [15]
  • ChEMBL [11]
  • Gene Ontology [11]
  • Pfam [10]
Sort by: Download
Showing 1 - 10 of 34. Page 1 of 4
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EMD-69297
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3D View
Cryo-EM structure of the UnCas12m4a-crRNA-tgDNA ternary complex in the TS-cleaving state
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.69 Å
EM Method: Single-particle
Fitted PDBs: 23vu
Q-score: 0.623
Similar entry percentile: 91%

Morinaga H, Omura SN, Alfonse L, Ornstein A, Kobayashi TA, Onishi K, Makarova KS, Shmakov SA, Munoz G, Garrity AJ, DiTommaso T, Koonin EV, Maben Z, Nureki O

To Be Published

EMD-69298
Download Map
3D View
Cryo-EM structure of the UnCas12m4a-crRNA-tgDNA ternary complex in the NTS-cleaving state
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 23vv
Q-score: 0.581
Similar entry percentile: 86%

Morinaga H, Omura SN, Alfonse L, Ornstein A, Kobayashi TA, Onishi K, Makarova KS, Shmakov SA, Munoz G, Garrity AJ, DiTommaso T, Koonin EV, Maben Z, Nureki O

To Be Published

EMD-69299
Download Map
3D View
Cryo-EM structure of the TfCas12m3-crRNA-tgDNA ternary complex
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.39 Å
EM Method: Single-particle
Fitted PDBs: 23vw
Q-score: 0.629
Similar entry percentile: 80%

Morinaga H, Omura SN, Alfonse L, Ornstein A, Kobayashi TA, Onishi K, Makarova KS, Shmakov SA, Munoz G, Garrity AJ, DiTommaso T, Koonin EV, Maben Z, Nureki O

To Be Published

EMD-63767
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3D View
Cryo-EM structure of wild-type SaCas9-guide RNA-mismatched target DNA complex
CryoEM
Release date: March 18, 2026
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 9mb6

Omura SN, Nakagawa R, Kajimoto S, Okazaki S, Ishiguro S, Mori H, Onishi K, Kashiwakura Y, Hiramoto T, Horinaka K, Tanaka M, Hirano H, Jividen K, Yamashita K, Tsai SQ, Yachie N, Ohmori T, Nishimasu H, Nureki O

Nat Commun (2026) 17 [ DOI: doi:10.1038/s41467-026-71626-2 Pubmed: 41991526 ]

EMD-63768
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3D View
Cryo-EM structure of eSaCas9-NNG-guide RNA-mismatched target DNA complex
CryoEM
Release date: March 18, 2026
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 9mb7

Omura SN, Nakagawa R, Kajimoto S, Okazaki S, Ishiguro S, Mori H, Onishi K, Kashiwakura Y, Hiramoto T, Horinaka K, Tanaka M, Hirano H, Jividen K, Yamashita K, Tsai SQ, Yachie N, Ohmori T, Nishimasu H, Nureki O

Nat Commun (2026) 17 [ DOI: doi:10.1038/s41467-026-71626-2 Pubmed: 41991526 ]

EMD-39941
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3D View
Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in an interrogation state
CryoEM
Release date: Nov. 5, 2025
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 8zcy
Q-score: 0.342
Similar entry percentile: 8%

Omura SN, Nakagawa R, Kajimoto S, Okazaki S, Ishiguro S, Mori H, Onishi K, Kashiwakura Y, Hiramoto T, Horinaka K, Tanaka M, Hirano H, Jividen K, Yamashita K, Tsai SQ, Yachie N, Ohmori T, Nishimasu H, Nureki O

Nat Commun (2026) 17 [ DOI: doi:10.1038/s41467-026-71626-2 Pubmed: 41991526 ]

EMD-39942
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3D View
Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in an intermediate state
CryoEM
Release date: Nov. 5, 2025
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8zcz
Q-score: 0.484
Similar entry percentile: 41%

Omura SN, Nakagawa R, Kajimoto S, Okazaki S, Ishiguro S, Mori H, Onishi K, Kashiwakura Y, Hiramoto T, Horinaka K, Tanaka M, Hirano H, Jividen K, Yamashita K, Tsai SQ, Yachie N, Ohmori T, Nishimasu H, Nureki O

Nat Commun (2026) 17 [ DOI: doi:10.1038/s41467-026-71626-2 Pubmed: 41991526 ]

EMD-39944
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3D View
Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in a translocation state
CryoEM
Release date: Nov. 5, 2025
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8zd0
Q-score: 0.572
Similar entry percentile: 78%

Omura SN, Nakagawa R, Kajimoto S, Okazaki S, Ishiguro S, Mori H, Onishi K, Kashiwakura Y, Hiramoto T, Horinaka K, Tanaka M, Hirano H, Jividen K, Yamashita K, Tsai SQ, Yachie N, Ohmori T, Nishimasu H, Nureki O

Nat Commun (2026) 17 [ DOI: doi:10.1038/s41467-026-71626-2 Pubmed: 41991526 ]

EMD-39954
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3D View
Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in a catalytically active state
CryoEM
Release date: Nov. 5, 2025
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8zda
Q-score: 0.478
Similar entry percentile: 50%

Omura SN, Nakagawa R, Kajimoto S, Okazaki S, Ishiguro S, Mori H, Onishi K, Kashiwakura Y, Hiramoto T, Horinaka K, Tanaka M, Hirano H, Jividen K, Yamashita K, Tsai SQ, Yachie N, Ohmori T, Nishimasu H, Nureki O

Nat Commun (2026) 17 [ DOI: doi:10.1038/s41467-026-71626-2 Pubmed: 41991526 ]

EMD-61037
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3D View
Cryo-EM structure of CasLambda2-crRNA binary complex
CryoEM
Release date: June 11, 2025
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 9izm
Q-score: 0.479
Similar entry percentile: 45%

Omura SN, Alfonse LE, Ornstein A, Morinaga H, Hirano H, Itoh Y, Munoz G, Garrity AJ, Hoffman GR, DiTommaso T, Yan WX, Cheng DR, Scott DA, Maben Z, Nureki O

Commun Biol (2025) 8 pp. 876-876 [ DOI: doi:10.1038/s42003-025-08300-8 Pubmed: 40473912 ]

Sort by: Download
Showing 1 - 10 of 34. Page 1 of 4
Display:
Statistics
×

Download


Preview 10 entries View All Download file

Filter By

Current Database

  • EMDB [34]

Current status

  • REL [34]

Sample type

  • Complex [34]
  • Protein [26]
  • RNA [26]
  • DNA [24]
  • Ligand [18]
  • Other [1]

Organism

  • Streptococcus pyogenes [12]
  • Staphylococcus aureus [6]
  • Streptococcus pyogenes [5]
  • Murine leukemia virus [4]
  • Mycolicibacterium mucogenicum [4]
  • Lachnospiraceae bacterium nd2006 [3]
  • Acidibacillus sulfuroxidans [3]
  • Bacterium [2]
  • Deinococcus radiodurans [2]
  • Thermanaerosceptrum fracticalcis [1]
  • Dna molecule [1]

EM Method

  • Single-particle [34]

Resolution

  • ≥ 2Å and < 3Å [13]
  • ≥ 3Å and < 4Å [18]
  • ≥ 4Å and < 5Å [2]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [22]
  • 250-500 kDa [4]

Release Date

  • 2026 [5]
  • 2025 [17]
  • 2024 [5]
  • 2023 [7]

Author by name

  • Nureki O [34]
  • Omura SN [34]
  • Hirano H [31]
  • Nakagawa R [26]
  • Itoh Y [25]
  • Shuto Y [14]
  • Zhang F [14]
  • Hoki M [13]
  • Zhu S [13]
  • Hiramoto T [9]
  • Ishiguro S [9]
  • Mori H [9]
  • Ohmori T [9]
  • Onishi K [9]
  • Yachie N [9]
  • Ditommaso T [8]
  • Garrity AJ [8]
  • Hisato H [8]
  • Maben Z [8]
  • Mizuki H [8]
  • Morinaga H [8]
  • Munoz G [8]
  • Ornstein A [8]
  • Satoshi NO [8]
  • Yuzuru I [8]
  • Kise Y [7]
  • Horinaka K [6]
  • Jividen K [6]
  • Kajimoto S [6]
  • Kashiwakura Y [6]
  • Nishimasu H [6]
  • Okazaki S [6]
  • Omura NS [6]
  • Tanaka M [6]
  • Tsai SQ [6]
  • Yamashita K [6]
  • Alfonse LE [5]
  • Cheng DR [5]
  • Hoffman GR [5]
  • Scott DA [5]
  • Yan WX [5]
  • Kusakizako T [4]
  • Wu WY [4]
  • Van Der Oost J [4]
  • Aburatani H [3]
  • Alfonse L [3]
  • Hino T [3]
  • Hoshino A [3]
  • Ishiguro H [3]
  • Kagieva M [3]
  • Karvelis T [3]
  • Kirita Y [3]
  • Kobayashi TA [3]
  • Koonin EV [3]
  • Laffeber C [3]
  • Lebbink HGJ [3]
  • Lebbink JHG [3]
  • Makarova KS [3]
  • Matoba S [3]
  • Motooka D [3]
  • Oost VDJ [3]
  • Ozaki Y [3]
  • Shmakov SA [3]
  • Siksnys V [3]
  • Sudfeld C [3]
  • Takeda NS [3]
  • Takeda SN [3]
  • Tasaka S [3]
  • Togashi T [3]
  • Tokuyama T [3]
  • Uosaki H [3]
  • Villegas Warren R [3]
  • Warren VR [3]
  • Wu YW [3]
  • Yamano H [3]
  • Altae-tran H [1]
  • Dohmae N [1]
  • Kannan S [1]
  • Nakayama H [1]
  • Nety S [1]
  • Ohira T [1]
  • Omura S [1]
  • Osamu N [1]
  • Ryoya N [1]
  • Sakaguchi Y [1]
  • Sano FK [1]
  • Shuto O [1]
  • Suzuki T [1]
  • Tanaka T [1]
  • Yao X [1]
  • Yutaro S [1]

Author by ORCID

  • Nureki O [22]
  • Omura SN [19]
  • Itoh Y [13]
  • Zhang F [8]
  • Shuto Y [8]
  • Ohmori T [6]
  • Tsai SQ [6]
  • Nishimasu H [6]
  • Ishiguro S [6]
  • Yamashita K [6]
  • Kashiwakura Y [6]
  • Hiramoto T [6]
  • Mori H [6]
  • Onishi K [6]
  • Ditommaso T [5]
  • Alfonse LE [5]
  • Van Der Oost J [3]
  • Kusakizako T [3]
  • Lebbink JHG [3]
  • Villegas Warren R [3]

Journal

  • NATURE [14]
  • NAT COMMUN [6]
  • COMMUN BIOL [5]
  • CELL [3]
  • NAT STRUCT MOL BIOL [3]
  • TO BE PUBLISHED [3]

Software

  • CRYOSPARC [3]

Microscope

  • FEI TITAN KRIOS [20]
  • TFS KRIOS [14]

Electron Source

  • FIELD EMISSION GUN [34]

Film or detector model

  • GATAN K3 6K X 4K [25]
  • GATAN K3 BIOQUANTUM 6K X 4K [9]

External links

  • PDB [26]
  • ChEBI [18]
  • DrugBank [18]
  • AlphaFold DB [17]
  • UniProt [17]
  • PDBe-Kb [16]
  • InterPro [15]
  • ChEMBL [11]
  • Gene Ontology [11]
  • Pfam [10]