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author:"Mooney RA"

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Current Database

  • EMDB [31]
  • EMPIAR [5]

Current status

  • REL [36]

Sample type

  • Complex [31]
  • Ligand [30]
  • Protein [30]
  • DNA [27]
  • RNA [22]
  • Other [1]

Organism

  • Escherichia coli [19]
  • Synthetic construct [12]
  • Mycobacterium tuberculosis [9]
  • Escherichia coli [9]
  • Salmonella enterica [2]

EM Method

  • Single-particle [31]

Resolution

  • ≥ 2Å and < 3Å [7]
  • ≥ 3Å and < 4Å [18]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [3]
  • ≥ 6Å and < 8Å [2]

Model molecular weight

  • 250-500 kDa [28]
  • 1-2 MDa [1]

Release Date

  • 2026 [8]
  • 2025 [6]
  • 2023 [5]
  • 2022 [6]
  • 2018 [9]
  • 2017 [2]

Author by name

  • Landick R [34]
  • Mooney RA [34]
  • Darst SA [31]
  • Campbell EA [18]
  • Brewer JJ [11]
  • Saba J [11]
  • Lilic M [10]
  • Bao Y [8]
  • Buscher J [8]
  • Engstrom MD [8]
  • Liu J [8]
  • Mueller AU [8]
  • Omollo EO [8]
  • Sah B [8]
  • Wolfe MB [8]
  • Boyaci H [7]
  • Chen J [7]
  • Bosch B [6]
  • Chait BT [6]
  • Gelles J [6]
  • Inlow K [6]
  • Marcelino LP [6]
  • Olinares PDB [6]
  • Delbeau M [5]
  • Froom R [5]
  • Kang JY [5]
  • Koh S [5]
  • Mishanina TV [5]
  • Palka M [5]
  • Rock J [5]
  • Artsimovitch I [3]
  • Feng Y [3]
  • He D [3]
  • Nedialkov Y [3]
  • Shen L [3]
  • Shi J [3]
  • Wen A [3]
  • Wu X [3]
  • You L [3]
  • You LL [3]
  • Yu C [3]
  • Zeng Y [3]
  • Zhang Y [3]
  • Bellecourt MJ [2]
  • Cramer P [2]
  • Kohler R [2]
  • Mills DJ [2]

Author by ORCID

  • Landick R [15]
  • Omollo EO [8]
  • Mueller AU [8]
  • Campbell EA [7]
  • Darst SA [7]
  • Mishanina TV [5]
  • Rock J [5]
  • Koh S [5]
  • Chen J [4]
  • Yu C [3]
  • Marcelino LP [3]
  • Saba J [3]
  • Gelles J [3]
  • Zhang Y [3]
  • Wu X [3]
  • Inlow K [3]
  • Brewer JJ [3]
  • Chait BT [3]
  • Feng Y [3]
  • Zeng Y [3]
  • Bellecourt MJ [2]
  • Kohler R [1]
  • Cramer P [1]
  • Mills DJ [1]
  • Mooney RA [1]

Journal

  • BIORXIV [8]
  • ELIFE [7]
  • MOL CELL [7]
  • NAT STRUCT MOL BIOL [6]
  • TO BE PUBLISHED [4]
  • CELL [3]
  • NATURE [3]
  • SCIENCE [1]

Software

  • RELION [10]
  • CRYOSPARC [8]

Microscope

  • FEI TITAN KRIOS [19]
  • TFS KRIOS [8]
  • FEI POLARA 300 [2]
  • FEI TALOS ARCTICA [2]

Electron Source

  • FIELD EMISSION GUN [31]

Film or detector model

  • GATAN K3 6K X 4K [17]
  • GATAN K2 SUMMIT 4K X 4K [14]

EMPIAR Experiment type

  • EMDB [5]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [5]

External links

  • PDB [30]
  • AlphaFold DB [29]
  • ChEBI [29]
  • ChEMBL [29]
  • DrugBank [29]
  • UniProt [29]
  • PDBe-Kb [20]
  • Complex Portal [19]
  • Gene Ontology [19]
  • Pfam [19]
  • InterPro [11]
  • EMDB [5]
  • CATH [4]
  • EMPIAR [2]
  • SCOP2 [1]
Sort by: Download
Showing 1 - 10 of 36. Page 1 of 4
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EMD-76371
Download Map
3D View
Half-translocated RNA polymerase elemental paused elongation complex, swiveled with ppGpp ePEC swiveled ppGpp
CryoEM
Release date: July 1, 2026
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 12eb
Q-score: 0.51
Similar entry percentile: 48%

Mueller AU, Mooney RA, Engstrom MD, Bao Y, Wolfe MB, Sah B, Buscher J, Saba J, Liu J, Darst SA, Landick R

bioRxiv (2026) [ DOI: doi:10.64898/2026.05.13.724835 Pubmed: 42182161 ]

EMD-76372
Download Map
3D View
Half-translocated RNA polymerase elemental paused elongation complex, swiveled ePEC swiveled
CryoEM
Release date: July 1, 2026
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 12ec
Q-score: 0.545
Similar entry percentile: 55%

Mueller AU, Mooney RA, Engstrom MD, Bao Y, Wolfe MB, Sah B, Buscher J, Saba J, Liu J, Darst SA, Landick R

bioRxiv (2026) [ DOI: doi:10.64898/2026.05.13.724835 Pubmed: 42182161 ]

EMD-76373
Download Map
3D View
Pre-translocated RNA polymerase elemental paused elongation complex, TL open with ppGpp ePEC open ppGpp
CryoEM
Release date: July 1, 2026
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 12ed
Q-score: 0.487
Similar entry percentile: 48%

Mueller AU, Mooney RA, Engstrom MD, Bao Y, Wolfe MB, Sah B, Buscher J, Saba J, Liu J, Darst SA, Landick R

bioRxiv (2026) [ DOI: doi:10.64898/2026.05.13.724835 Pubmed: 42182161 ]

EMD-76374
Download Map
3D View
Pre-translocated RNA polymerase elemental paused elongation complex, TL open ePEC open
CryoEM
Release date: July 1, 2026
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 12ee
Q-score: 0.52
Similar entry percentile: 54%

Mueller AU, Mooney RA, Engstrom MD, Bao Y, Wolfe MB, Sah B, Buscher J, Saba J, Liu J, Darst SA, Landick R

bioRxiv (2026) [ DOI: doi:10.64898/2026.05.13.724835 Pubmed: 42182161 ]

EMD-76375
Download Map
3D View
Pre-translocated RNA polymerase elemental paused elongation complex, TL semiclosed with ppGpp ePEC semiclosed ppGpp
CryoEM
Release date: July 1, 2026
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 12ef
Q-score: 0.471
Similar entry percentile: 45%

Mueller AU, Mooney RA, Engstrom MD, Bao Y, Wolfe MB, Sah B, Buscher J, Saba J, Liu J, Darst SA, Landick R

bioRxiv (2026) [ DOI: doi:10.64898/2026.05.13.724835 Pubmed: 42182161 ]

EMD-76376
Download Map
3D View
Pre-translocated RNA polymerase elemental paused elongation complex, TL semiclosed ePEC semiclosed
CryoEM
Release date: July 1, 2026
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 12eg
Q-score: 0.524
Similar entry percentile: 56%

Mueller AU, Mooney RA, Engstrom MD, Bao Y, Wolfe MB, Sah B, Buscher J, Saba J, Liu J, Darst SA, Landick R

bioRxiv (2026) [ DOI: doi:10.64898/2026.05.13.724835 Pubmed: 42182161 ]

EMD-76377
Download Map
3D View
Pre-translocated RNA polymerase elemental paused elongation complex, TL closed with ppGpp ePEC closed ppGpp
CryoEM
Release date: July 1, 2026
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 12eh
Q-score: 0.455
Similar entry percentile: 42%

Mueller AU, Mooney RA, Engstrom MD, Bao Y, Wolfe MB, Sah B, Buscher J, Saba J, Liu J, Darst SA, Landick R

bioRxiv (2026) [ DOI: doi:10.64898/2026.05.13.724835 Pubmed: 42182161 ]

EMD-76378
Download Map
3D View
Pre-translocated RNA polymerase elemental paused elongation complex, TL closed ePEC closed
CryoEM
Release date: July 1, 2026
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 12ei
Q-score: 0.535
Similar entry percentile: 62%

Mueller AU, Mooney RA, Engstrom MD, Bao Y, Wolfe MB, Sah B, Buscher J, Saba J, Liu J, Darst SA, Landick R

bioRxiv (2026) [ DOI: doi:10.64898/2026.05.13.724835 Pubmed: 42182161 ]

EMPIAR-12594
Related EMDB
EMD-40930
Cryo-EM of RNAP post-terminal complexes on negatively supercoiled DNA
Release date: July 25, 2025
Dataset size: 1.3 TB
Experiment type: EMDB

Brewer JJ, Inlow K, Mooney RA, Bosch B, Olinares PDB, Marcelino LP, Chait BT, Landick R, Gelles J, Campbell EA, Darst SA

Nat Struct Mol Biol (2025) [ Pubmed: 39779919 DOI: 10.1038/s41594-024-01447-8 ]

Image sets:
  • Unaligned raw movies
EMPIAR-12595
Related EMDB
EMD-40943
Cryo-EM of RNAP post-terminal complexes bound to RapA+ADP+AlF3 on negatively supercoiled DNA
Release date: April 9, 2025
Dataset size: 1.7 TB
Experiment type: EMDB

Brewer JJ, Inlow K, Mooney RA, Bosch B, Olinares PDB, Marcelino LP, Chait BT, Landick R, Gelles J, Campbell EA, Darst SA

Nat Struct Mol Biol (2025) [ Pubmed: 39779919 DOI: 10.1038/s41594-024-01447-8 ]

Image sets:
  • Unaligned raw movies
Sort by: Download
Showing 1 - 10 of 36. Page 1 of 4
Display:
Statistics
×

Download



Preview 10 entries View All Download file

Filter By

Current Database

  • EMDB [31]
  • EMPIAR [5]

Current status

  • REL [36]

Sample type

  • Complex [31]
  • Ligand [30]
  • Protein [30]
  • DNA [27]
  • RNA [22]
  • Other [1]

Organism

  • Escherichia coli [19]
  • Synthetic construct [12]
  • Mycobacterium tuberculosis [9]
  • Escherichia coli [9]
  • Salmonella enterica [2]

EM Method

  • Single-particle [31]

Resolution

  • ≥ 2Å and < 3Å [7]
  • ≥ 3Å and < 4Å [18]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [3]
  • ≥ 6Å and < 8Å [2]

Model molecular weight

  • 250-500 kDa [28]
  • 1-2 MDa [1]

Release Date

  • 2026 [8]
  • 2025 [6]
  • 2023 [5]
  • 2022 [6]
  • 2018 [9]
  • 2017 [2]

Author by name

  • Landick R [34]
  • Mooney RA [34]
  • Darst SA [31]
  • Campbell EA [18]
  • Brewer JJ [11]
  • Saba J [11]
  • Lilic M [10]
  • Bao Y [8]
  • Buscher J [8]
  • Engstrom MD [8]
  • Liu J [8]
  • Mueller AU [8]
  • Omollo EO [8]
  • Sah B [8]
  • Wolfe MB [8]
  • Boyaci H [7]
  • Chen J [7]
  • Bosch B [6]
  • Chait BT [6]
  • Gelles J [6]
  • Inlow K [6]
  • Marcelino LP [6]
  • Olinares PDB [6]
  • Delbeau M [5]
  • Froom R [5]
  • Kang JY [5]
  • Koh S [5]
  • Mishanina TV [5]
  • Palka M [5]
  • Rock J [5]
  • Artsimovitch I [3]
  • Feng Y [3]
  • He D [3]
  • Nedialkov Y [3]
  • Shen L [3]
  • Shi J [3]
  • Wen A [3]
  • Wu X [3]
  • You L [3]
  • You LL [3]
  • Yu C [3]
  • Zeng Y [3]
  • Zhang Y [3]
  • Bellecourt MJ [2]
  • Cramer P [2]
  • Kohler R [2]
  • Mills DJ [2]

Author by ORCID

  • Landick R [15]
  • Omollo EO [8]
  • Mueller AU [8]
  • Campbell EA [7]
  • Darst SA [7]
  • Mishanina TV [5]
  • Rock J [5]
  • Koh S [5]
  • Chen J [4]
  • Yu C [3]
  • Marcelino LP [3]
  • Saba J [3]
  • Gelles J [3]
  • Zhang Y [3]
  • Wu X [3]
  • Inlow K [3]
  • Brewer JJ [3]
  • Chait BT [3]
  • Feng Y [3]
  • Zeng Y [3]
  • Bellecourt MJ [2]
  • Kohler R [1]
  • Cramer P [1]
  • Mills DJ [1]
  • Mooney RA [1]

Journal

  • BIORXIV [8]
  • ELIFE [7]
  • MOL CELL [7]
  • NAT STRUCT MOL BIOL [6]
  • TO BE PUBLISHED [4]
  • CELL [3]
  • NATURE [3]
  • SCIENCE [1]

Software

  • RELION [10]
  • CRYOSPARC [8]

Microscope

  • FEI TITAN KRIOS [19]
  • TFS KRIOS [8]
  • FEI POLARA 300 [2]
  • FEI TALOS ARCTICA [2]

Electron Source

  • FIELD EMISSION GUN [31]

Film or detector model

  • GATAN K3 6K X 4K [17]
  • GATAN K2 SUMMIT 4K X 4K [14]

EMPIAR Experiment type

  • EMDB [5]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [5]

External links

  • PDB [30]
  • AlphaFold DB [29]
  • ChEBI [29]
  • ChEMBL [29]
  • DrugBank [29]
  • UniProt [29]
  • PDBe-Kb [20]
  • Complex Portal [19]
  • Gene Ontology [19]
  • Pfam [19]
  • InterPro [11]
  • EMDB [5]
  • CATH [4]
  • EMPIAR [2]
  • SCOP2 [1]