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author:"Mankin A"

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Current Database

  • EMDB [10]
  • EMPIAR [1]

Current status

  • REL [11]

Sample type

  • Complex [10]
  • Ligand [6]
  • Protein [6]
  • RNA [6]

Organism

  • Escherichia coli [7]
  • Streptococcus sanguinis [3]
  • Escherichia coli [3]
  • Paenibacillus larvae [2]
  • Synthetic construct [2]
  • Escherichia coli [1]

EM Method

  • Single-particle [10]

Resolution

  • ≥ 2Å and < 3Å [9]
  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 2-5 MDa [6]

Release Date

  • 2026 [7]
  • 2024 [4]

Author by name

  • Morici M [11]
  • Mankin A [10]
  • Vazquez-laslop N [10]
  • Wilson DN [10]
  • Av-gay Y [7]
  • Berger M [7]
  • Corazza M [7]
  • Dhar N [7]
  • Ejim L [7]
  • Klepacki D [7]
  • Safdari HA [7]
  • Sahile H [7]
  • Travin D [7]
  • Wang L [7]
  • Wang W [7]
  • Wright G [7]
  • Xu M [7]
  • Yarlagadda V [7]
  • Beckert B [4]
  • Berger MJ [4]
  • Cook MA [4]
  • Fitzgerald M [4]
  • Golas AJ [4]
  • Guitor AK [4]
  • Hung DT [4]
  • Koller TO [4]
  • Lin S [4]
  • Nietupski RM [4]
  • Rao VN [4]
  • Schaenzer AJ [4]
  • Bond A [3]
  • Bulatov T [3]
  • Chhabra N [3]
  • Cook M [3]
  • Crowe-mcauliffe C [3]
  • Dang T [3]
  • Di Stasi A [3]
  • Gomez J [3]
  • Guitor A [3]
  • Hackenberger D [3]
  • Hung D [3]
  • Mainz A [3]
  • Mardirossian M [3]
  • Paternoga H [3]
  • Rao V [3]
  • Raulf K [3]
  • Safdari H [3]
  • Schaenzer A [3]
  • Scocchi M [3]
  • Surette M [3]
  • Sussmuth RD [3]
  • Tertigas D [3]
  • Wilson D [3]

Author by ORCID

  • Wilson DN [7]
  • Cook MA [4]
  • Morici M [4]
  • Safdari HA [4]
  • Berger M [4]
  • Corazza M [4]
  • Sussmuth RD [3]
  • Gomez J [3]
  • Mankin A [3]
  • Dang T [3]
  • Dhar N [3]
  • Xu M [3]
  • Wright G [3]
  • Av-gay Y [3]
  • Surette M [3]
  • Travin D [3]
  • Vazquez-laslop N [3]
  • Hung D [3]
  • Bond A [3]

Journal

  • TO BE PUBLISHED [4]
  • BIORXIV [3]
  • RES SQ [3]

Software

  • RELION [7]

Microscope

  • TFS KRIOS [7]
  • FEI TITAN KRIOS [3]

Electron Source

  • FIELD EMISSION GUN [10]

Film or detector model

  • GATAN K3 6K X 4K [7]
  • FEI FALCON IV 4K X 4K [3]

EMPIAR Experiment type

  • EMDB [1]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [1]

External links

  • AlphaFold DB [6]
  • ChEBI [6]
  • ChEMBL [6]
  • DrugBank [6]
  • Gene Ontology [6]
  • InterPro [6]
  • PDB [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • Complex Portal [4]
  • EMPIAR [2]
  • EMDB [1]
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Showing 1 - 10 of 11. Page 1 of 2
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EMD-56520
Download Map
3D View
Cryo-EM map of SKM-70S complex State 2 Accommodating A-tRNA
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.3 Å
EM Method: Single-particle

Cook MA, Xu M, Wang W, Rao VN, Schaenzer AJ, Wang L, Yarlagadda V, Guitor AK, Ejim L, Wright G, Golas AJ, Nietupski RM, Fitzgerald M, Hung DT, Sahile H, Av-Gay Y, Lin S, Dhar N, Travin D, Klepacki D, Vazquez-Laslop N, Mankin A, Morici M, Corazza M, Safdari HA, Berger M, Wilson DN

To Be Published

EMD-56525
Download Map
3D View
Cryo-EM map of SKM-70S complex State 4 Accommodated A-tRNA
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.3 Å
EM Method: Single-particle

Cook MA, Xu M, Wang W, Rao VN, Schaenzer AJ, Wang L, Yarlagadda V, Guitor AK, Ejim L, Wright G, Golas AJ, Nietupski RM, Fitzgerald M, Hung DT, Sahile H, Av-Gay Y, Lin S, Dhar N, Travin D, Klepacki D, Vazquez-Laslop N, Mankin A, Morici M, Corazza M, Safdari HA, Berger M, Wilson DN

To Be Published

EMD-56530
Download Map
3D View
Cryo-EM map of SKM-70S complex State 6 Empty, canonical
CryoEM
Release date: Sept. 2, 2026
Resolution: 2.75 Å
EM Method: Single-particle

Cook MA, Xu M, Wang W, Rao VN, Schaenzer AJ, Wang L, Yarlagadda V, Guitor AK, Ejim L, Wright G, Golas AJ, Nietupski RM, Fitzgerald M, Hung DT, Sahile H, Av-Gay Y, Lin S, Dhar N, Travin D, Klepacki D, Vazquez-Laslop N, Mankin A, Morici M, Corazza M, Safdari HA, Berger M, Wilson DN

To Be Published

EMD-57122
Download Map
3D View
Cryo-EM map of SKM-70S complex State 7 Empty, rotated
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.42 Å
EM Method: Single-particle

Cook MA, Xu M, Wang W, Rao VN, Schaenzer AJ, Wang L, Yarlagadda V, Guitor AK, Ejim L, Wright G, Golas AJ, Nietupski RM, Fitzgerald M, Hung DT, Sahile H, Av-Gay Y, Lin S, Dhar N, Travin D, Klepacki D, Vazquez-Laslop N, Mankin A, Morici M, Corazza M, Safdari HA, Berger M, Wilson DN

To Be Published

EMD-53311
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3D View
Cryo-EM map of SKM-70S ribosomal stalled complex in the major state vacant A-site, canon
CryoEM
Release date: Feb. 18, 2026
Resolution: 2.26 Å
EM Method: Single-particle
Fitted PDBs: 9qqq
Q-score: 0.617
Similar entry percentile: 65%

Wright G, Cook M, Xu M, Morici M, Travin D, Wang W, Klepacki D, Chhabra N, Rao V, Sahile H, Hackenberger D, Safdari H, Berger M, Corazza M, Bond A, Guitor A, Tertigas D, Wang L, Schaenzer A, Ejim L, Yarlagadda V, Gomez J, Surette M, Av-Gay Y, Dhar N, Hung D, Vazquez-Laslop N, Mankin A, Wilson D

Res Sq (2025) [ Pubmed: 41282059 DOI: doi:10.21203/rs.3.rs-7820265/v1 ]

EMD-53341
Download Map
3D View
Cryo-EM structure of SKM-70S ribosomal stalled complex in the A-tRNA positioned Body open state.
CryoEM
Release date: Feb. 18, 2026
Resolution: 2.62 Å
EM Method: Single-particle
Fitted PDBs: 9qsj
Q-score: 0.613
Similar entry percentile: 87%

Wright G, Cook M, Xu M, Morici M, Travin D, Wang W, Klepacki D, Chhabra N, Rao V, Sahile H, Hackenberger D, Safdari H, Berger M, Corazza M, Bond A, Guitor A, Tertigas D, Wang L, Schaenzer A, Ejim L, Yarlagadda V, Gomez J, Surette M, Av-Gay Y, Dhar N, Hung D, Vazquez-Laslop N, Mankin A, Wilson D

Res Sq (2025) [ Pubmed: 41282059 DOI: doi:10.21203/rs.3.rs-7820265/v1 ]

EMD-55145
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3D View
Cryo-EM structure of SKM-70S ribosomal stalled complex in the rotated state with hybrid tRNAs
CryoEM
Release date: Feb. 18, 2026
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 9sro
Q-score: 0.583
Similar entry percentile: 76%

Wright G, Cook M, Xu M, Morici M, Travin D, Wang W, Klepacki D, Chhabra N, Rao V, Sahile H, Hackenberger D, Safdari H, Berger M, Corazza M, Bond A, Guitor A, Tertigas D, Wang L, Schaenzer A, Ejim L, Yarlagadda V, Gomez J, Surette M, Av-Gay Y, Dhar N, Hung D, Vazquez-Laslop N, Mankin A, Wilson D

Res Sq (2025) [ Pubmed: 41282059 DOI: doi:10.21203/rs.3.rs-7820265/v1 ]

EMPIAR-12080
Related EMDB
EMD-19004 EMD-18950
cryo electron microscopy unaligned movie frames for single particle analysis of the Escherichia coli 70S ribosome with Paenilamicin B2
Release date: Sept. 6, 2024
Dataset size: 4.3 TB
Experiment type: EMDB

Koller TO, Berger MJ, Morici M, Paternoga H, Bulatov T, di Stasi A, Raulf K, Crowe-McAuliffe C, Mardirossian M, Beckert B, Suessmuth RD, Mankin A, Wilson DN

To Be Published

Image sets:
  • Unaligned movies in EER format of a cryo-EM data collection of antimicrobial peptide paenilamicin B2 of Paenibacillus larvae bound to the 70S E.coli ribosome.
EMD-18950
Download Map
3D View
Raw data
EMPIAR-12080
70S Escherichia coli ribosome with Paenilamicin B2 bound with A- and P-site tRNA.
CryoEM
Release date: July 24, 2024
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8r6c
Q-score: 0.668
Similar entry percentile: 83%

Koller TO, Berger MJ, Morici M, Paternoga H, Bulatov T, Di Stasi A, Dang T, Mainz A, Raulf K, Crowe-McAuliffe C, Scocchi M, Mardirossian M, Beckert B, Vazquez-Laslop N, Mankin A, Sussmuth RD, Wilson DN

bioRxiv (2024) [ Pubmed: 38826346 DOI: doi:10.1101/2024.05.21.595107 ]

EMD-19004
Download Map
3D View
Raw data
EMPIAR-12080
70S Escherichia coli ribosome with Paenilamicin B2 bound with hybrid A/P- and hybrid P/E-tRNA.
CryoEM
Release date: July 24, 2024
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8r8m
Q-score: 0.634
Similar entry percentile: 84%

Koller TO, Berger MJ, Morici M, Paternoga H, Bulatov T, Di Stasi A, Dang T, Mainz A, Raulf K, Crowe-McAuliffe C, Scocchi M, Mardirossian M, Beckert B, Vazquez-Laslop N, Mankin A, Sussmuth RD, Wilson DN

bioRxiv (2024) [ Pubmed: 38826346 DOI: doi:10.1101/2024.05.21.595107 ]

Sort by: Download
Showing 1 - 10 of 11. Page 1 of 2
Display:
Statistics
×

Download



Preview 10 entries View All Download file

Filter By

Current Database

  • EMDB [10]
  • EMPIAR [1]

Current status

  • REL [11]

Sample type

  • Complex [10]
  • Ligand [6]
  • Protein [6]
  • RNA [6]

Organism

  • Escherichia coli [7]
  • Streptococcus sanguinis [3]
  • Escherichia coli [3]
  • Paenibacillus larvae [2]
  • Synthetic construct [2]
  • Escherichia coli [1]

EM Method

  • Single-particle [10]

Resolution

  • ≥ 2Å and < 3Å [9]
  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 2-5 MDa [6]

Release Date

  • 2026 [7]
  • 2024 [4]

Author by name

  • Morici M [11]
  • Mankin A [10]
  • Vazquez-laslop N [10]
  • Wilson DN [10]
  • Av-gay Y [7]
  • Berger M [7]
  • Corazza M [7]
  • Dhar N [7]
  • Ejim L [7]
  • Klepacki D [7]
  • Safdari HA [7]
  • Sahile H [7]
  • Travin D [7]
  • Wang L [7]
  • Wang W [7]
  • Wright G [7]
  • Xu M [7]
  • Yarlagadda V [7]
  • Beckert B [4]
  • Berger MJ [4]
  • Cook MA [4]
  • Fitzgerald M [4]
  • Golas AJ [4]
  • Guitor AK [4]
  • Hung DT [4]
  • Koller TO [4]
  • Lin S [4]
  • Nietupski RM [4]
  • Rao VN [4]
  • Schaenzer AJ [4]
  • Bond A [3]
  • Bulatov T [3]
  • Chhabra N [3]
  • Cook M [3]
  • Crowe-mcauliffe C [3]
  • Dang T [3]
  • Di Stasi A [3]
  • Gomez J [3]
  • Guitor A [3]
  • Hackenberger D [3]
  • Hung D [3]
  • Mainz A [3]
  • Mardirossian M [3]
  • Paternoga H [3]
  • Rao V [3]
  • Raulf K [3]
  • Safdari H [3]
  • Schaenzer A [3]
  • Scocchi M [3]
  • Surette M [3]
  • Sussmuth RD [3]
  • Tertigas D [3]
  • Wilson D [3]

Author by ORCID

  • Wilson DN [7]
  • Cook MA [4]
  • Morici M [4]
  • Safdari HA [4]
  • Berger M [4]
  • Corazza M [4]
  • Sussmuth RD [3]
  • Gomez J [3]
  • Mankin A [3]
  • Dang T [3]
  • Dhar N [3]
  • Xu M [3]
  • Wright G [3]
  • Av-gay Y [3]
  • Surette M [3]
  • Travin D [3]
  • Vazquez-laslop N [3]
  • Hung D [3]
  • Bond A [3]

Journal

  • TO BE PUBLISHED [4]
  • BIORXIV [3]
  • RES SQ [3]

Software

  • RELION [7]

Microscope

  • TFS KRIOS [7]
  • FEI TITAN KRIOS [3]

Electron Source

  • FIELD EMISSION GUN [10]

Film or detector model

  • GATAN K3 6K X 4K [7]
  • FEI FALCON IV 4K X 4K [3]

EMPIAR Experiment type

  • EMDB [1]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [1]

External links

  • AlphaFold DB [6]
  • ChEBI [6]
  • ChEMBL [6]
  • DrugBank [6]
  • Gene Ontology [6]
  • InterPro [6]
  • PDB [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • Complex Portal [4]
  • EMPIAR [2]
  • EMDB [1]