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author:"Macrae RK"

Filter By

Current Database

  • EMDB [38]
  • EMPIAR [7]

Current status

  • REL [45]

Sample type

  • Complex [38]
  • Protein [30]
  • RNA [27]
  • Ligand [26]
  • DNA [23]

Organism

  • Synthetic construct [19]
  • Spizellomyces punctatus [7]
  • Desulfonema ishimotonii [6]
  • Escherichia phage phiv-1 [5]
  • Parasitella parasitica [4]
  • Saccharomyces cerevisiae [4]
  • Escherichia coli [4]
  • Guillardia theta [3]
  • Metagenome [2]
  • Salmonella enterica [2]
  • Desulfovirgula thermocuniculi [2]
  • Klebsiella pneumoniae [2]
  • Homo sapiens [2]
  • Selenomonas sp. [1]
  • Thermoproteota archaeon [1]
  • Uncultured prevotellaceae bacterium [1]
  • Taeniopygia guttata [1]
  • Bombyx mori [1]

EM Method

  • Single-particle [38]

Resolution

  • ≥ 2Å and < 3Å [11]
  • ≥ 3Å and < 4Å [25]
  • ≥ 4Å and < 5Å [1]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [20]
  • 250-500 kDa [5]
  • 500-1000 kDa [1]
  • 1-2 MDa [1]
  • 2-5 MDa [1]

Release Date

  • 2025 [9]
  • 2024 [18]
  • 2023 [4]
  • 2022 [14]

Author by name

  • Zhang F [45]
  • Macrae RK [42]
  • Wilkinson ME [41]
  • Faure G [29]
  • Xu P [17]
  • Saito M [16]
  • Maguire S [14]
  • Chau-Duy-Tam Vo S [13]
  • Kuang H [13]
  • Rice WJ [13]
  • Wang B [13]
  • Strecker J [12]
  • Koonin EV [11]
  • Li D [10]
  • Demircioglu FE [9]
  • Makarova KS [9]
  • Altae-tran H [7]
  • Kannan S [7]
  • Nishimasu H [7]
  • Abudayyeh OO [6]
  • Gootenberg JS [6]
  • Gao L [5]
  • Gao LA [5]
  • Lash B [4]
  • Zhu S [4]
  • Gao A [3]
  • Hirano S [3]
  • Madigan V [3]
  • Puccio E [3]
  • Raghavan R [3]
  • Segel M [3]
  • Strebinger D [3]
  • Zhang Y [3]
  • Edmonds KK [2]
  • Evgeniou L [2]
  • Flam-shepherd D [2]
  • Frangieh CJ [2]
  • Kappel K [2]
  • Kim S [2]
  • Mears KS [2]
  • Quinones-olvera N [2]
  • Reddy N [2]
  • Seiichi H [2]
  • Shiozaki M [2]
  • Yan R [2]
  • Yu Z [2]
  • Zilberzwige-tal S [2]
  • Chen H [1]
  • Desimone A [1]
  • Edmonds KHK [1]
  • Esra Demircioglu F [1]
  • Fukuda M [1]
  • Isayama Y [1]
  • Ishikawa J [1]
  • Kato K [1]
  • Ladha A [1]
  • Liu D [1]
  • Moeller L [1]
  • Ni HM [1]
  • Nishizawa T [1]
  • Okazaki O [1]
  • Okazaki S [1]
  • Oshiro R [1]
  • Pham J [1]
  • Schaefer CC [1]
  • Shmakov S [1]
  • Vaz Reay Na [1]
  • Vo S [1]
  • Vo SC [1]
  • Walsh ML [1]
  • Wang X [1]
  • Yao CJ [1]

Author by ORCID

  • Zhang F [21]
  • Wilkinson ME [20]
  • Macrae RK [18]
  • Saito M [15]
  • Wang B [13]
  • Faure G [12]
  • Strecker J [11]
  • Koonin EV [9]
  • Makarova KS [8]
  • Li D [8]
  • Nishimasu H [7]
  • Demircioglu FE [6]
  • Abudayyeh OO [6]
  • Gootenberg JS [6]
  • Gao LA [5]
  • Kannan S [4]
  • Zhang F [3]
  • Raghavan R [2]
  • Zhang Y [2]
  • Hirano S [2]
  • Kappel K [2]
  • Gao A [2]
  • Yu Z [2]
  • Xu P [2]
  • Frangieh CJ [2]
  • Walsh ML [1]
  • Reddy N [1]
  • Vo S [1]
  • Liu D [1]
  • Nishizawa T [1]
  • Strebinger D [1]
  • Zilberzwige-tal S [1]
  • Quinones-olvera N [1]
  • Edmonds KK [1]
  • Chen H [1]
  • Altae-tran H [1]
  • Lash B [1]
  • Ishikawa J [1]
  • Vaz Reay Na [1]
  • Zhu S [1]
  • Schaefer CC [1]
  • Evgeniou L [1]
  • Maguire S [1]

Journal

  • SCIENCE [19]
  • CELL [14]
  • NAT COMMUN [3]
  • NATURE [3]
  • PNAS [3]
  • MOL CELL [1]
  • NAT BIOTECHNOL [1]
  • TO BE PUBLISHED [1]

Software

  • RELION [13]
  • CTFFIND [1]

Microscope

  • FEI TITAN KRIOS [34]
  • TFS KRIOS [3]
  • FEI TALOS ARCTICA [1]

Electron Source

  • FIELD EMISSION GUN [37]
  • OTHER [1]

Film or detector model

  • GATAN K3 6K X 4K [26]
  • GATAN K3 BIOQUANTUM 6K X 4K [11]
  • FEI FALCON III 4K X 4K [1]

EMPIAR Experiment type

  • EMDB [7]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [7]

External links

  • PDB [37]
  • ChEBI [25]
  • DrugBank [25]
  • UniProt [24]
  • ChEMBL [22]
  • PDBe-Kb [21]
  • AlphaFold DB [20]
  • EMPIAR [13]
  • InterPro [11]
  • Pfam [9]
  • Gene Ontology [8]
  • EMDB [7]
  • Complex Portal [1]
Sort by: Download
Showing 1 - 10 of 45. Page 1 of 5
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EMPIAR-12962
Related EMDB
EMD-43682
Cryo-EM micrographs of PbAbiF dimer bound to ncRNA
Release date: Dec. 7, 2025
Dataset size: 587.8 GB
Experiment type: EMDB

Zilberzwige-Tal S, Altae-Tran H, Kannan S, Wilkinson ME, Vo SC, Strebinger D, Edmonds KK, Yao CJ, Mears KS, Shmakov SA, Makarova KS, Macrae RK, Koonin EV, Zhang F

Cell (2025) 188 pp. 1925-1940.e20 [ Pubmed: 39970912 DOI: 10.1016/j.cell.2025.01.034 ]

Image sets:
  • Unaligned multi-frame movies of PbAbiF RNP
EMPIAR-12960
Related EMDB
EMD-47091
Cryo-EM micrographs of R2Tg retrotransposon initiating target-primed reverse transcription
Release date: Nov. 30, 2025
Dataset size: 1.7 TB
Experiment type: EMDB

Edmonds KK, Wilkinson ME, Strebinger D, Chen H, Lash B, Schaefer CC, Zhu S, Liu D, Zilberzwige-Tal S, Ladha A, Walsh ML, Frangieh CJ, Vaz Reay NA, Macrae RK, Wang X, Zhang F

Nat Commun (2025) 16 [ DOI: 10.1038/s41467-025-61321-z Pubmed: 40603868 ]

Image sets:
  • Unaligned multi-frame movies of Taeniopygia guttata R2 retrotransposon initiating target-primed reverse transcription
EMPIAR-12322
Related EMDB
EMD-45086 EMD-45085
Cryo-EM micrographs for the DRT2 reverse transcriptase / ncRNA complex in resting and elongating states
Release date: June 2, 2025
Dataset size: 6.2 TB
Experiment type: EMDB

Wilkinson ME, Li D, Gao A, Macrae RK, Zhang F

Science (2024) [ DOI: 10.1126/science.adq3977 Pubmed: 39208082 ]

Image sets:
  • Unaligned multi-frame movies of DRT2 ribonucleoprotein complex in the resting state (no added dNTPs)
  • Unaligned multi-frame movies of DRT2 ribonucleoprotein complex in the elongating state (+dNTPs)
EMD-47091
Download Map
3D View
Raw data
EMPIAR-12960
Taeniopygia guttata R2 retrotransposon R2Tg initiating target-primed reverse transcription
CryoEM
Release date: May 21, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9dou
Q-score: 0.535

Edmonds KK, Wilkinson ME, Strebinger D, Chen H, Lash B, Schaefer CC, Zhu S, Liu D, Zilberzwige-Tal S, Ladha A, Walsh ML, Frangieh CJ, Vaz Reay NA, Macrae RK, Wang X, Zhang F

Nat Commun (2025) 16 pp. 6079-6079 [ DOI: doi:10.1038/s41467-025-61321-z Pubmed: 40603868 ]

EMD-49856
Download Map
3D View
Engineered OrufIscB-omegaRNA-target DNA complex
CryoEM
Release date: May 21, 2025
Resolution: 2.71 Å
EM Method: Single-particle
Fitted PDBs: 9nvu
Q-score: 0.518

Kannan S, Altae-Tran H, Zhu S, Xu P, Strebinger D, Oshiro R, Faure G, Moeller L, Pham J, Mears KS, Ni HM, Macrae RK, Zhang F

Nat Biotechnol (2026) 44 pp. 759-770 [ DOI: doi:10.1038/s41587-025-02655-3 Pubmed: 40335752 ]

EMPIAR-12312
Related EMDB
EMD-42812
Cryo-EM micrographs for a recombinant human PNMA2 capsid
Release date: April 24, 2025
Dataset size: 1.8 TB
Experiment type: EMDB

Madigan V, Zhang Y, Raghavan R, Wilkinson ME, Faure G, Puccio E, Segel M, Lash B, Macrae RK, Zhang F

Proc Natl Acad Sci U S A (2024) 121 pp. e2307812120-308 [ DOI: 10.1073/pnas.2307812120 Pubmed: 38437549 ]

Image sets:
  • Unaligned multi-frame movies of recombinant PNMA2
EMPIAR-12705
Related EMDB
EMD-48616
Cryo-EM micrographs of TIGR-TasR in complex with tigRNA and target DNA after DNA cleavage
Release date: April 23, 2025
Dataset size: 1.9 TB
Experiment type: EMDB

Faure G, Saito M, Wilkinson ME, Quinones-Olvera N, Xu P, Flam-Shepherd D, Kim S, Reddy N, Zhu S, Evgeniou L, Koonin EV, Macrae RK, Zhang F

Science (2025) [ Pubmed: 40014690 DOI: 10.1126/science.adv9789 ]

Image sets:
  • Unaligned multi-frame movies of the TIGR-TasR RNP bound to target DNA
EMD-48616
Download Map
3D View
Raw data
EMPIAR-12705
Structure of TIGR-TasR in complex with tigRNA and target DNA after DNA cleavage
CryoEM
Release date: March 5, 2025
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 9mty
Q-score: 0.536

Faure G, Saito M, Wilkinson ME, Quinones-Olvera N, Xu P, Flam-Shepherd D, Kim S, Reddy N, Zhu S, Evgeniou L, Koonin EV, Macrae RK, Zhang F

Science (2025) 388 pp. eadv9789-eadv9789 [ Pubmed: 40014690 DOI: doi:10.1126/science.adv9789 ]

EMD-43682
Download Map
3D View
Raw data
EMPIAR-12962
PbAbiF dimer bound to ncRNA
CryoEM
Release date: Feb. 12, 2025
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 8vz6
Q-score: 0.48

Zilberzwige-Tal S, Altae-Tran H, Kannan S, Wilkinson ME, Vo SC, Shmakov S, Yao CJ, Strebinger D, Edmonds KK, Mears KS, Makarova KS, Macrae RK, Koonin EV, Zhang F

To Be Published

EMD-45516
Download Map
3D View
Guillardia theta Fanzor GtFz State 1
CryoEM
Release date: Sept. 11, 2024
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 9cer
Q-score: 0.197

Xu P, Saito M, Faure G, Maguire S, Chau-Duy-Tam Vo S, Wilkinson ME, Kuang H, Wang B, Rice WJ, Macrae RK, Zhang F

Cell (2024) 187 pp. 5238-5252.e20 [ DOI: doi:10.1016/j.cell.2024.07.050 Pubmed: 39208796 ]

Sort by: Download
Showing 1 - 10 of 45. Page 1 of 5
Display:
Statistics
×

Download












































Preview first 10
Download

Filter By

Current Database

  • EMDB [38]
  • EMPIAR [7]

Current status

  • REL [45]

Sample type

  • Complex [38]
  • Protein [30]
  • RNA [27]
  • Ligand [26]
  • DNA [23]

Organism

  • Synthetic construct [19]
  • Spizellomyces punctatus [7]
  • Desulfonema ishimotonii [6]
  • Escherichia phage phiv-1 [5]
  • Parasitella parasitica [4]
  • Saccharomyces cerevisiae [4]
  • Escherichia coli [4]
  • Guillardia theta [3]
  • Metagenome [2]
  • Salmonella enterica [2]
  • Desulfovirgula thermocuniculi [2]
  • Klebsiella pneumoniae [2]
  • Homo sapiens [2]
  • Selenomonas sp. [1]
  • Thermoproteota archaeon [1]
  • Uncultured prevotellaceae bacterium [1]
  • Taeniopygia guttata [1]
  • Bombyx mori [1]

EM Method

  • Single-particle [38]

Resolution

  • ≥ 2Å and < 3Å [11]
  • ≥ 3Å and < 4Å [25]
  • ≥ 4Å and < 5Å [1]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [20]
  • 250-500 kDa [5]
  • 500-1000 kDa [1]
  • 1-2 MDa [1]
  • 2-5 MDa [1]

Release Date

  • 2025 [9]
  • 2024 [18]
  • 2023 [4]
  • 2022 [14]

Author by name

  • Zhang F [45]
  • Macrae RK [42]
  • Wilkinson ME [41]
  • Faure G [29]
  • Xu P [17]
  • Saito M [16]
  • Maguire S [14]
  • Chau-Duy-Tam Vo S [13]
  • Kuang H [13]
  • Rice WJ [13]
  • Wang B [13]
  • Strecker J [12]
  • Koonin EV [11]
  • Li D [10]
  • Demircioglu FE [9]
  • Makarova KS [9]
  • Altae-tran H [7]
  • Kannan S [7]
  • Nishimasu H [7]
  • Abudayyeh OO [6]
  • Gootenberg JS [6]
  • Gao L [5]
  • Gao LA [5]
  • Lash B [4]
  • Zhu S [4]
  • Gao A [3]
  • Hirano S [3]
  • Madigan V [3]
  • Puccio E [3]
  • Raghavan R [3]
  • Segel M [3]
  • Strebinger D [3]
  • Zhang Y [3]
  • Edmonds KK [2]
  • Evgeniou L [2]
  • Flam-shepherd D [2]
  • Frangieh CJ [2]
  • Kappel K [2]
  • Kim S [2]
  • Mears KS [2]
  • Quinones-olvera N [2]
  • Reddy N [2]
  • Seiichi H [2]
  • Shiozaki M [2]
  • Yan R [2]
  • Yu Z [2]
  • Zilberzwige-tal S [2]
  • Chen H [1]
  • Desimone A [1]
  • Edmonds KHK [1]
  • Esra Demircioglu F [1]
  • Fukuda M [1]
  • Isayama Y [1]
  • Ishikawa J [1]
  • Kato K [1]
  • Ladha A [1]
  • Liu D [1]
  • Moeller L [1]
  • Ni HM [1]
  • Nishizawa T [1]
  • Okazaki O [1]
  • Okazaki S [1]
  • Oshiro R [1]
  • Pham J [1]
  • Schaefer CC [1]
  • Shmakov S [1]
  • Vaz Reay Na [1]
  • Vo S [1]
  • Vo SC [1]
  • Walsh ML [1]
  • Wang X [1]
  • Yao CJ [1]

Author by ORCID

  • Zhang F [21]
  • Wilkinson ME [20]
  • Macrae RK [18]
  • Saito M [15]
  • Wang B [13]
  • Faure G [12]
  • Strecker J [11]
  • Koonin EV [9]
  • Makarova KS [8]
  • Li D [8]
  • Nishimasu H [7]
  • Demircioglu FE [6]
  • Abudayyeh OO [6]
  • Gootenberg JS [6]
  • Gao LA [5]
  • Kannan S [4]
  • Zhang F [3]
  • Raghavan R [2]
  • Zhang Y [2]
  • Hirano S [2]
  • Kappel K [2]
  • Gao A [2]
  • Yu Z [2]
  • Xu P [2]
  • Frangieh CJ [2]
  • Walsh ML [1]
  • Reddy N [1]
  • Vo S [1]
  • Liu D [1]
  • Nishizawa T [1]
  • Strebinger D [1]
  • Zilberzwige-tal S [1]
  • Quinones-olvera N [1]
  • Edmonds KK [1]
  • Chen H [1]
  • Altae-tran H [1]
  • Lash B [1]
  • Ishikawa J [1]
  • Vaz Reay Na [1]
  • Zhu S [1]
  • Schaefer CC [1]
  • Evgeniou L [1]
  • Maguire S [1]

Journal

  • SCIENCE [19]
  • CELL [14]
  • NAT COMMUN [3]
  • NATURE [3]
  • PNAS [3]
  • MOL CELL [1]
  • NAT BIOTECHNOL [1]
  • TO BE PUBLISHED [1]

Software

  • RELION [13]
  • CTFFIND [1]

Microscope

  • FEI TITAN KRIOS [34]
  • TFS KRIOS [3]
  • FEI TALOS ARCTICA [1]

Electron Source

  • FIELD EMISSION GUN [37]
  • OTHER [1]

Film or detector model

  • GATAN K3 6K X 4K [26]
  • GATAN K3 BIOQUANTUM 6K X 4K [11]
  • FEI FALCON III 4K X 4K [1]

EMPIAR Experiment type

  • EMDB [7]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [7]

External links

  • PDB [37]
  • ChEBI [25]
  • DrugBank [25]
  • UniProt [24]
  • ChEMBL [22]
  • PDBe-Kb [21]
  • AlphaFold DB [20]
  • EMPIAR [13]
  • InterPro [11]
  • Pfam [9]
  • Gene Ontology [8]
  • EMDB [7]
  • Complex Portal [1]