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author:"Liang WG"

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Current Database

  • EMDB [22]
  • EMPIAR [2]

Current status

  • REL [24]

Sample type

  • Complex [21]
  • Protein [21]
  • Cellular component [1]
  • Ligand [1]

Organism

  • Homo sapiens [19]
  • Mycobacterium tuberculosis [2]
  • Escherichia phage ecszw-2 [1]

EM Method

  • Single-particle [21]
  • Tomography [1]

Resolution

  • ≥ 3Å and < 4Å [10]
  • ≥ 4Å and < 5Å [5]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [5]

Model molecular weight

  • 50-100 kDa [2]
  • 100-250 kDa [14]
  • 250-500 kDa [5]

Release Date

  • 2026 [1]
  • 2022 [8]
  • 2021 [5]
  • 2020 [2]
  • 2018 [5]
  • 2017 [3]

Author by name

  • Liang WG [24]
  • Tang WJ [23]
  • Carragher B [21]
  • Potter CS [21]
  • Wei H [21]
  • Lee D [15]
  • Li S [15]
  • Mancl JM [15]
  • Zhao M [10]
  • Bailey LJ [8]
  • Deprez B [8]
  • Deprez-poulain R [8]
  • Farcasanu M [8]
  • Koide A [8]
  • Koide S [8]
  • Kossiakoff AA [8]
  • Liu DR [8]
  • Mccord LA [8]
  • Potter SC [8]
  • Shang W [8]
  • Tan YZ [8]
  • Wang A [8]
  • Woods VA [8]
  • Zhang Z [8]
  • Koehler CM [7]
  • Lin King Jv [7]
  • Liu C [7]
  • Mo S [7]
  • Noble AJ [7]
  • Pan M [7]
  • Wijaya J [7]
  • Bayhi NL [5]
  • Budell W [5]
  • Mendez JH [5]
  • Sosnick TR [5]
  • Liang W [1]
  • Tang W [1]

Author by ORCID

  • Lee D [13]
  • Carragher B [13]
  • Tang WJ [13]
  • Tan YZ [8]
  • Deprez-poulain R [8]
  • Potter CS [8]
  • Zhao M [5]
  • Wei H [5]
  • Pan M [5]
  • Noble AJ [5]
  • Liu C [5]
  • Li S [5]
  • Mancl JM [3]

Journal

  • ELIFE [14]
  • NAT COMMUN [7]
  • STRUCTURE [2]
  • RESEARCH SQUARE [1]
  • TO BE PUBLISHED [1]

Software

  • RELION [16]
  • CTFFIND [6]
  • TOMO3D [1]

Microscope

  • FEI TITAN KRIOS [21]
  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [22]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [14]
  • GATAN K3 6K X 4K [7]
  • GATAN K2 QUANTUM 4K X 4K [1]

EMPIAR Experiment type

  • EMDB [2]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [2]
  • MICROGRAPHS - SINGLE FRAME [1]
  • RECONSTRUCTED VOLUMES [1]

External links

  • PDB [22]
  • AlphaFold DB [21]
  • UniProt [21]
  • PDBe-Kb [20]
  • Pfam [20]
  • Gene Ontology [19]
  • InterPro [19]
  • Complex Portal [15]
  • EMPIAR [7]
  • CATH [2]
  • EMDB [2]
  • ChEBI [1]
  • ChEMBL [1]
  • DrugBank [1]
Sort by: Download
Showing 1 - 10 of 24. Page 1 of 3
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EMD-72393
Download Map
3D View
Raw data
EMPIAR-12968
Insulin Degrading Enzyme Time-resolved O/O state
CryoEM
Release date: May 6, 2026
Resolution: 5.1 Å
EM Method: Single-particle
Fitted PDBs: 9y0h
Q-score: 0.047

Mancl JM, Liang WG, Wei H, Carragher B, Potter CS, Tang WJ

eLife (2025) [ DOI: doi:10.7554/eLife.105761.1 ]

EMD-24757
Download Map
3D View
Insulin Degrading Enzyme pO/pC
CryoEM
Release date: Aug. 31, 2022
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7rze
Q-score: 0.47

Mancl JM, Liang WG, Bayhi NL, Wei H, Budell W, Mendez JH, Sosnick TR, Carragher B, Potter CS, Tang WJ

eLife (2026) [ DOI: doi:10.7554/elife.105761.3 ]

EMD-24758
Download Map
3D View
Insulin Degrading Enzyme O/pC
CryoEM
Release date: Aug. 31, 2022
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7rzf
Q-score: 0.417

Mancl JM, Liang WG, Bayhi NL, Wei H, Budell W, Mendez JH, Sosnick TR, Carragher B, Potter CS, Tang WJ

eLife (2026) [ DOI: doi:10.7554/elife.105761.3 ]

EMD-24759
Download Map
3D View
Insulin Degrading Enzyme O/pO
CryoEM
Release date: Aug. 31, 2022
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7rzg
Q-score: 0.329

Mancl JM, Liang WG, Bayhi NL, Wei H, Budell W, Mendez JH, Sosnick TR, Carragher B, Potter CS, Tang WJ

eLife (2026) [ DOI: doi:10.7554/elife.105761.3 ]

EMD-24760
Download Map
3D View
Insulin Degrading Enzyme O/O
CryoEM
Release date: Aug. 31, 2022
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7rzh
Q-score: 0.234

Mancl JM, Liang WG, Bayhi NL, Wei H, Budell W, Mendez JH, Sosnick TR, Carragher B, Potter CS, Tang WJ

eLife (2026) [ DOI: doi:10.7554/elife.105761.3 ]

EMD-24761
Download Map
3D View
Insulin Degrading Enzyme pC/pC
CryoEM
Release date: Aug. 31, 2022
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7rzi
Q-score: 0.54

Mancl JM, Liang WG, Bayhi NL, Wei H, Budell W, Mendez JH, Sosnick TR, Carragher B, Potter CS, Tang WJ

eLife (2026) [ DOI: doi:10.7554/elife.105761.3 ]

EMPIAR-10937
Related EMDB
EMD-22280 EMD-22281 EMD-22279 EMD-22282 EMD-22278
CryoEM of PreP prepared via Chameleon
Release date: March 21, 2022
Dataset size: 2.2 TB
Experiment type: EMDB

Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ

Nat Commun (2022) 13 [ Pubmed: 35383169 DOI: 10.1038/s41467-022-29322-4 ]

Image sets:
  • Apo-PreP micrographs
  • PreP half particles
  • Amyloid beta bound PreP
  • Citrate synthase presequence bound PreP
[Show more]
EMPIAR-10929
Related EMDB
EMD-25921
CryoET of presequence protease single particle
Release date: Jan. 28, 2022
Dataset size: 25.4 GB
Experiment type: EMDB

Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ

Nat Commun (2022) 13 [ Pubmed: 35383169 DOI: 10.1038/s41467-022-29322-4 ]

Image sets:
  • Binned by 4 tomograms from all 7 tilt-series
  • Unaligned K2 tilt image frame stacks
EMD-25921
Download Map
3D View
Raw data
EMPIAR-10929
CryoET of presequence protease single particle
CryoEM
Release date: Jan. 26, 2022
EM Method: Tomography

Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ

Nat Commun (2022) 13 pp. 1833-1833 [ Pubmed: 35383169 DOI: doi:10.1038/s41467-022-29322-4 ]

EMD-22278
Download Map
3D View
Raw data
EMPIAR-10937
CryoEM structure of human presequence protease in partial open state 1
CryoEM
Release date: July 7, 2021
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6xos
Q-score: 0.405

Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ

Nat Commun (2022) 13 pp. 1833-1833 [ Pubmed: 35383169 DOI: doi:10.1038/s41467-022-29322-4 ]

Sort by: Download
Showing 1 - 10 of 24. Page 1 of 3
Display:
Statistics
×

Download












































Preview first 10
Download

Filter By

Current Database

  • EMDB [22]
  • EMPIAR [2]

Current status

  • REL [24]

Sample type

  • Complex [21]
  • Protein [21]
  • Cellular component [1]
  • Ligand [1]

Organism

  • Homo sapiens [19]
  • Mycobacterium tuberculosis [2]
  • Escherichia phage ecszw-2 [1]

EM Method

  • Single-particle [21]
  • Tomography [1]

Resolution

  • ≥ 3Å and < 4Å [10]
  • ≥ 4Å and < 5Å [5]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [5]

Model molecular weight

  • 50-100 kDa [2]
  • 100-250 kDa [14]
  • 250-500 kDa [5]

Release Date

  • 2026 [1]
  • 2022 [8]
  • 2021 [5]
  • 2020 [2]
  • 2018 [5]
  • 2017 [3]

Author by name

  • Liang WG [24]
  • Tang WJ [23]
  • Carragher B [21]
  • Potter CS [21]
  • Wei H [21]
  • Lee D [15]
  • Li S [15]
  • Mancl JM [15]
  • Zhao M [10]
  • Bailey LJ [8]
  • Deprez B [8]
  • Deprez-poulain R [8]
  • Farcasanu M [8]
  • Koide A [8]
  • Koide S [8]
  • Kossiakoff AA [8]
  • Liu DR [8]
  • Mccord LA [8]
  • Potter SC [8]
  • Shang W [8]
  • Tan YZ [8]
  • Wang A [8]
  • Woods VA [8]
  • Zhang Z [8]
  • Koehler CM [7]
  • Lin King Jv [7]
  • Liu C [7]
  • Mo S [7]
  • Noble AJ [7]
  • Pan M [7]
  • Wijaya J [7]
  • Bayhi NL [5]
  • Budell W [5]
  • Mendez JH [5]
  • Sosnick TR [5]
  • Liang W [1]
  • Tang W [1]

Author by ORCID

  • Lee D [13]
  • Carragher B [13]
  • Tang WJ [13]
  • Tan YZ [8]
  • Deprez-poulain R [8]
  • Potter CS [8]
  • Zhao M [5]
  • Wei H [5]
  • Pan M [5]
  • Noble AJ [5]
  • Liu C [5]
  • Li S [5]
  • Mancl JM [3]

Journal

  • ELIFE [14]
  • NAT COMMUN [7]
  • STRUCTURE [2]
  • RESEARCH SQUARE [1]
  • TO BE PUBLISHED [1]

Software

  • RELION [16]
  • CTFFIND [6]
  • TOMO3D [1]

Microscope

  • FEI TITAN KRIOS [21]
  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [22]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [14]
  • GATAN K3 6K X 4K [7]
  • GATAN K2 QUANTUM 4K X 4K [1]

EMPIAR Experiment type

  • EMDB [2]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [2]
  • MICROGRAPHS - SINGLE FRAME [1]
  • RECONSTRUCTED VOLUMES [1]

External links

  • PDB [22]
  • AlphaFold DB [21]
  • UniProt [21]
  • PDBe-Kb [20]
  • Pfam [20]
  • Gene Ontology [19]
  • InterPro [19]
  • Complex Portal [15]
  • EMPIAR [7]
  • CATH [2]
  • EMDB [2]
  • ChEBI [1]
  • ChEMBL [1]
  • DrugBank [1]