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author:"Lei X"

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Current Database

  • EMDB [26]

Current status

  • REL [26]

Sample type

  • Protein [26]
  • Ligand [25]
  • Complex [24]
  • Cellular component [2]

Organism

  • Homo sapiens [21]
  • Synthetic construct [5]
  • Rattus norvegicus [3]
  • Mus musculus [2]
  • Arabidopsis thaliana [2]
  • Aequorea victoria [2]
  • Pseudotevenvirus rb43 [1]

EM Method

  • Single-particle [26]

Resolution

  • ≥ 2Å and < 3Å [9]
  • ≥ 3Å and < 4Å [16]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 50-100 kDa [8]
  • 100-250 kDa [4]
  • 250-500 kDa [8]
  • 500-1000 kDa [6]

Release Date

  • 2026 [2]
  • 2025 [7]
  • 2024 [8]
  • 2023 [4]
  • 2022 [5]

Author by name

  • Lei X [26]
  • Fan J [21]
  • Ke H [18]
  • Guo F [10]
  • Jiang D [8]
  • Liao D [8]
  • Xie W [7]
  • Lei J [6]
  • Tominaga M [6]
  • Yue Z [6]
  • Bai Y [5]
  • Wang J [5]
  • Chen H [4]
  • Chi C [4]
  • Chu H [4]
  • Chu HL [4]
  • Gao N [4]
  • Guo C [4]
  • Hang J [4]
  • Hu L [4]
  • Huang Z [4]
  • Li N [4]
  • Li R [4]
  • Li S [4]
  • Li Y [4]
  • Liu Y [4]
  • Meng X [4]
  • Qiao J [4]
  • Ren R [4]
  • Tang Y [4]
  • Tao L [4]
  • Wang G [4]
  • Wang GP [4]
  • Wang X [4]
  • Wei Y [4]
  • Wu D [4]
  • Yang J [4]
  • Yang Y [4]
  • Zhang C [4]
  • Zhong Q [4]
  • Zhong QH [4]
  • Zhou Y [4]
  • Guo N [3]
  • Wang H [3]
  • Zhang J [3]
  • Cao C [2]
  • Chen Y [2]
  • Deng XW [2]
  • Fan JP [2]
  • Huang B [2]
  • Jiang DH [2]
  • Jiang J [2]
  • Lan G [2]
  • Lei XG [2]
  • Li G [2]
  • Shen R [2]
  • Shi Y [2]
  • Wang C [2]
  • Wang K [2]
  • Yan R [2]
  • Yu H [2]
  • Zhang M [2]
  • Zhang W [2]
  • Zhao J [2]
  • Zhao T [2]
  • Zhou F [2]
  • Zhu W [2]
  • Zou H [2]
  • Chen L [1]
  • Cui W [1]
  • Liu R [1]
  • Niu Y [1]
  • Wang S [1]

Author by ORCID

  • Lei X [22]
  • Fan J [17]
  • Jiang D [8]
  • Lei J [6]
  • Tominaga M [6]
  • Li N [4]
  • Huang Z [4]
  • Hang J [4]
  • Tao L [4]
  • Yang Y [4]
  • Hu L [4]
  • Qiao J [4]
  • Ke H [4]
  • Gao N [4]
  • Ren R [4]
  • Xie W [4]
  • Tang Y [4]
  • Liao D [4]
  • Guo C [4]
  • Yu H [2]
  • Jiang J [2]
  • Zhou F [2]
  • Yang J [2]
  • Li Y [2]
  • Wu D [2]
  • Huang B [2]
  • Cao C [2]
  • Yan R [2]
  • Liu R [1]
  • Chen L [1]
  • Niu Y [1]
  • Cui W [1]
  • Wang S [1]

Journal

  • NAT CHEM BIOL [6]
  • ADV SCI [4]
  • CELL DISCOV [4]
  • JACS AU [3]
  • NAT COMMUN [3]
  • CELL [2]
  • MOL PLANT [2]
  • NATURE [2]

Software

  • CRYOSPARC [5]
  • RELION [4]

Microscope

  • FEI TITAN KRIOS [20]
  • TFS KRIOS [4]
  • TFS TITAN THEMIS [2]

Electron Source

  • FIELD EMISSION GUN [26]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [11]
  • GATAN K3 6K X 4K [11]
  • GATAN K2 QUANTUM 4K X 4K [4]

External links

  • AlphaFold DB [26]
  • PDB [26]
  • UniProt [26]
  • Pfam [21]
  • Gene Ontology [20]
  • PDBe-Kb [20]
  • InterPro [16]
  • ChEBI [13]
  • ChEMBL [12]
  • DrugBank [11]
  • Complex Portal [2]
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Showing 1 - 10 of 26. Page 1 of 3
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EMD-64829
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3D View
cryoEM structure of HEP-50768-bound MRGPRX4-Gq complex
CryoEM
Release date: May 6, 2026
Resolution: 2.63 Å
EM Method: Single-particle
Fitted PDBs: 9v81
Q-score: 0.592

Yang J, Shen R, Wang C, Zhu W, Ke H, Fan J, Zhang M, Liu Y, Li S, Li G, Wang X, Li Y, Cao C, Lei X

Nat Chem Biol (2026) [ DOI: doi:10.1038/s41589-026-02195-0 Pubmed: 41957282 ]

EMD-64830
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3D View
Local refine map of HEP-50768-bound MRGPRX4
CryoEM
Release date: May 6, 2026
Resolution: 2.56 Å
EM Method: Single-particle
Fitted PDBs: 9v82
Q-score: 0.599

Yang J, Shen R, Wang C, Zhu W, Ke H, Fan J, Zhang M, Liu Y, Li S, Li G, Wang X, Li Y, Cao C, Lei X

Nat Chem Biol (2026) [ DOI: doi:10.1038/s41589-026-02195-0 Pubmed: 41957282 ]

EMD-64489
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3D View
influx carrier substrate bound form
CryoEM
Release date: Dec. 24, 2025
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 9utd
Q-score: 0.514

Chen H, Fan J, Chi C, Zhao J, Wu D, Lei X, Deng XW, Jiang D

Mol Plant (2025) 18 pp. 1284-1293 [ Pubmed: 40579814 DOI: doi:10.1016/j.molp.2025.06.015 ]

EMD-64490
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influx carrier apo form
CryoEM
Release date: Dec. 24, 2025
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 9ute
Q-score: 0.544

Chen H, Fan J, Chi C, Zhao J, Wu D, Lei X, Deng XW, Jiang D

Mol Plant (2025) 18 pp. 1284-1293 [ Pubmed: 40579814 DOI: doi:10.1016/j.molp.2025.06.015 ]

EMD-63148
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Cryo-EM structure of human organic solute transporter OSTalpha/beta in apo state
CryoEM
Release date: Dec. 3, 2025
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 9ljg
Q-score: 0.602

Wang K, Fan J, Chen H, Huang B, Chi C, Yan R, Wu D, Zhou F, Zhang W, Jiang J, Lei X, Jiang D

Nature (2026) 651 pp. 251-259 [ DOI: doi:10.1038/s41586-025-09934-8 Pubmed: 41606314 ]

EMD-63149
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Cryo-EM structure of human organic solute transporter OSTalpha/beta in complex with DHEAS
CryoEM
Release date: Dec. 3, 2025
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 9ljh
Q-score: 0.594

Wang K, Fan J, Chen H, Huang B, Chi C, Yan R, Wu D, Zhou F, Zhang W, Jiang J, Lei X, Jiang D

Nature (2026) 651 pp. 251-259 [ DOI: doi:10.1038/s41586-025-09934-8 Pubmed: 41606314 ]

EMD-61155
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3D View
Cryo-EM Structure of URAT1 in Complex with Benzbromarone
CryoEM
Release date: Feb. 26, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9j5w
Q-score: 0.434

Fan J, Xie W, Ke H, Zhang J, Wang J, Wang H, Guo N, Bai Y, Lei X

Jacs Au (2025) 5 pp. 1308-1319 [ DOI: doi:10.1021/jacsau.4c01188 Pubmed: 40151250 ]

EMD-61156
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Cryo-EM Structure of URAT1 in Complex with Lingolinurad
CryoEM
Release date: Feb. 26, 2025
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 9j5x
Q-score: 0.455

Fan J, Xie W, Ke H, Zhang J, Wang J, Wang H, Guo N, Bai Y, Lei X

Jacs Au (2025) 5 pp. 1308-1319 [ DOI: doi:10.1021/jacsau.4c01188 Pubmed: 40151250 ]

EMD-61157
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Cryo-EM Structure of URAT1 in Complex with Verinurad
CryoEM
Release date: Feb. 26, 2025
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9j5z
Q-score: 0.455

Fan J, Xie W, Ke H, Zhang J, Wang J, Wang H, Guo N, Bai Y, Lei X

Jacs Au (2025) 5 pp. 1308-1319 [ DOI: doi:10.1021/jacsau.4c01188 Pubmed: 40151250 ]

EMD-36890
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3D View
CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P
CryoEM
Release date: Nov. 6, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8k4s
Q-score: 0.521

Yang J, Zhao T, Fan J, Zou H, Lan G, Guo F, Shi Y, Ke H, Yu H, Yue Z, Wang X, Bai Y, Li S, Liu Y, Wang X, Chen Y, Li Y, Lei X

Cell (2024) 187 pp. 7164-7182.e18 [ Pubmed: 39476841 DOI: doi:10.1016/j.cell.2024.10.001 ]

Sort by: Download
Showing 1 - 10 of 26. Page 1 of 3
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [26]

Current status

  • REL [26]

Sample type

  • Protein [26]
  • Ligand [25]
  • Complex [24]
  • Cellular component [2]

Organism

  • Homo sapiens [21]
  • Synthetic construct [5]
  • Rattus norvegicus [3]
  • Mus musculus [2]
  • Arabidopsis thaliana [2]
  • Aequorea victoria [2]
  • Pseudotevenvirus rb43 [1]

EM Method

  • Single-particle [26]

Resolution

  • ≥ 2Å and < 3Å [9]
  • ≥ 3Å and < 4Å [16]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 50-100 kDa [8]
  • 100-250 kDa [4]
  • 250-500 kDa [8]
  • 500-1000 kDa [6]

Release Date

  • 2026 [2]
  • 2025 [7]
  • 2024 [8]
  • 2023 [4]
  • 2022 [5]

Author by name

  • Lei X [26]
  • Fan J [21]
  • Ke H [18]
  • Guo F [10]
  • Jiang D [8]
  • Liao D [8]
  • Xie W [7]
  • Lei J [6]
  • Tominaga M [6]
  • Yue Z [6]
  • Bai Y [5]
  • Wang J [5]
  • Chen H [4]
  • Chi C [4]
  • Chu H [4]
  • Chu HL [4]
  • Gao N [4]
  • Guo C [4]
  • Hang J [4]
  • Hu L [4]
  • Huang Z [4]
  • Li N [4]
  • Li R [4]
  • Li S [4]
  • Li Y [4]
  • Liu Y [4]
  • Meng X [4]
  • Qiao J [4]
  • Ren R [4]
  • Tang Y [4]
  • Tao L [4]
  • Wang G [4]
  • Wang GP [4]
  • Wang X [4]
  • Wei Y [4]
  • Wu D [4]
  • Yang J [4]
  • Yang Y [4]
  • Zhang C [4]
  • Zhong Q [4]
  • Zhong QH [4]
  • Zhou Y [4]
  • Guo N [3]
  • Wang H [3]
  • Zhang J [3]
  • Cao C [2]
  • Chen Y [2]
  • Deng XW [2]
  • Fan JP [2]
  • Huang B [2]
  • Jiang DH [2]
  • Jiang J [2]
  • Lan G [2]
  • Lei XG [2]
  • Li G [2]
  • Shen R [2]
  • Shi Y [2]
  • Wang C [2]
  • Wang K [2]
  • Yan R [2]
  • Yu H [2]
  • Zhang M [2]
  • Zhang W [2]
  • Zhao J [2]
  • Zhao T [2]
  • Zhou F [2]
  • Zhu W [2]
  • Zou H [2]
  • Chen L [1]
  • Cui W [1]
  • Liu R [1]
  • Niu Y [1]
  • Wang S [1]

Author by ORCID

  • Lei X [22]
  • Fan J [17]
  • Jiang D [8]
  • Lei J [6]
  • Tominaga M [6]
  • Li N [4]
  • Huang Z [4]
  • Hang J [4]
  • Tao L [4]
  • Yang Y [4]
  • Hu L [4]
  • Qiao J [4]
  • Ke H [4]
  • Gao N [4]
  • Ren R [4]
  • Xie W [4]
  • Tang Y [4]
  • Liao D [4]
  • Guo C [4]
  • Yu H [2]
  • Jiang J [2]
  • Zhou F [2]
  • Yang J [2]
  • Li Y [2]
  • Wu D [2]
  • Huang B [2]
  • Cao C [2]
  • Yan R [2]
  • Liu R [1]
  • Chen L [1]
  • Niu Y [1]
  • Cui W [1]
  • Wang S [1]

Journal

  • NAT CHEM BIOL [6]
  • ADV SCI [4]
  • CELL DISCOV [4]
  • JACS AU [3]
  • NAT COMMUN [3]
  • CELL [2]
  • MOL PLANT [2]
  • NATURE [2]

Software

  • CRYOSPARC [5]
  • RELION [4]

Microscope

  • FEI TITAN KRIOS [20]
  • TFS KRIOS [4]
  • TFS TITAN THEMIS [2]

Electron Source

  • FIELD EMISSION GUN [26]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [11]
  • GATAN K3 6K X 4K [11]
  • GATAN K2 QUANTUM 4K X 4K [4]

External links

  • AlphaFold DB [26]
  • PDB [26]
  • UniProt [26]
  • Pfam [21]
  • Gene Ontology [20]
  • PDBe-Kb [20]
  • InterPro [16]
  • ChEBI [13]
  • ChEMBL [12]
  • DrugBank [11]
  • Complex Portal [2]