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author:"Lauer ME"

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Current Database

  • EMDB [5]
  • EMPIAR [2]

Current status

  • REL [7]

Sample type

  • Complex [5]
  • Protein [5]

Organism

  • Homo sapiens [5]

EM Method

  • Helical reconstruction [5]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [4]

Model molecular weight

  • 100-250 kDa [5]

Release Date

  • 2020 [1]
  • 2019 [4]
  • 2018 [2]

Author by name

  • Britschgi M [7]
  • Guerrero-ferreira R [7]
  • Lauer ME [7]
  • Mona D [7]
  • Riek R [7]
  • Ringler P [7]
  • Stahlberg H [7]
  • Taylor NM [7]
  • Arteni AA [5]
  • Bousset L [5]
  • Kumari P [5]
  • Makky A [5]
  • Meier BH [5]
  • Melki R [5]
  • Taylor NMI [5]
  • Verasdonck J [5]
  • Bockmann A [4]
  • Böckmann A [1]

Author by ORCID

  • Britschgi M [5]
  • Stahlberg H [5]
  • Guerrero-ferreira R [5]
  • Riek R [5]
  • Taylor NM [5]
  • Lauer ME [5]
  • Ringler P [5]
  • Arteni AA [4]
  • Bockmann A [4]
  • Bousset L [4]
  • Makky A [4]
  • Kumari P [4]
  • Meier BH [4]

Journal

  • ELIFE [7]
  • BIORXIV [2]

Software

  • RELION [5]
  • COOT [4]

Microscope

  • FEI TITAN KRIOS [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [5]

EMPIAR Experiment type

  • EMDB [2]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [1]
  • MICROGRAPHS - SINGLE FRAME [1]

External links

  • AlphaFold DB [5]
  • Complex Portal [5]
  • Gene Ontology [5]
  • InterPro [5]
  • PDB [5]
  • PDBe-Kb [5]
  • Pfam [5]
  • UniProt [5]
  • EMDB [2]
  • EMPIAR [2]
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EMPIAR-10323
Related EMDB
EMD-10307 EMD-10305
Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy
Release date: March 4, 2020
Dataset size: 90.9 GB
Experiment type: EMDB

Guerrero-Ferreira R, Taylor NM, Arteni AA, Kumari P, Mona D, Ringler P, Britschgi M, Lauer ME, Makky A, Verasdonck J, Riek R, Melki R, Meier BH, Böckmann A, Bousset L, Stahlberg H

eLife (2019) 8 [ Pubmed: 31815671 DOI: 10.7554/eLife.48907 ]

Image sets:
  • Aligned micrographs of alpha-synuclein fibrils
EMD-10305
Download Map
3D View
Raw data
EMPIAR-10323
cryo-em structure of alpha-synuclein fibril polymorph 2B
CryoEM
Release date: Dec. 18, 2019
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 6sst
Q-score: 0.511
Similar entry percentile: 79%

Guerrero-Ferreira R, Taylor NM, Arteni AA, Kumari P, Mona D, Ringler P, Britschgi M, Lauer ME, Makky A, Verasdonck J, Riek R, Melki R, Meier BH, Bockmann A, Bousset L, Stahlberg H

eLife (2019) 8 [ DOI: doi:10.7554/eLife.48907 Pubmed: 31815671 ]

EMD-10307
Download Map
3D View
Raw data
EMPIAR-10323
cryo-em structure of alpha-synuclein fibril polymorph 2A
CryoEM
Release date: Dec. 18, 2019
Resolution: 2.98 Å
EM Method: Helical reconstruction
Fitted PDBs: 6ssx
Q-score: 0.551
Similar entry percentile: 78%

Guerrero-Ferreira R, Taylor NM, Arteni AA, Kumari P, Mona D, Ringler P, Britschgi M, Lauer ME, Makky A, Verasdonck J, Riek R, Melki R, Meier BH, Bockmann A, Bousset L, Stahlberg H

eLife (2019) 8 [ DOI: doi:10.7554/eLife.48907 Pubmed: 31815671 ]

EMD-4994
Download Map
3D View
cryo-em of alpha-synuclein fibril polymorph 2A
CryoEM
Release date: June 26, 2019
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 6rt0
Q-score: 0.573
Similar entry percentile: 91%

Guerrero-Ferreira R, Taylor NM, Arteni AA, Kumari P, Mona D, Ringler P, Britschgi M, Lauer ME, Makky A, Verasdonck J, Riek R, Melki R, Meier BH, Bockmann A, Bousset L, Stahlberg H

eLife (2019) 8 [ DOI: doi:10.7554/eLife.48907 Pubmed: 31815671 ]

EMD-4996
Download Map
3D View
cryo-em structure of alpha-synuclein fibril polymorph 2B
CryoEM
Release date: June 26, 2019
Resolution: 3.46 Å
EM Method: Helical reconstruction
Fitted PDBs: 6rtb
Q-score: 0.511
Similar entry percentile: 82%

Guerrero-Ferreira R, Taylor NM, Arteni AA, Kumari P, Mona D, Ringler P, Britschgi M, Lauer ME, Makky A, Verasdonck J, Riek R, Melki R, Meier BH, Bockmann A, Bousset L, Stahlberg H

eLife (2019) 8 [ DOI: doi:10.7554/eLife.48907 Pubmed: 31815671 ]

EMD-0148
Download Map
3D View
Structure of alpha-synuclein fibrils
CryoEM
Release date: Aug. 8, 2018
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 6h6b
Q-score: 0.469
Similar entry percentile: 59%

Guerrero-Ferreira R, Taylor NM, Mona D, Ringler P, Lauer ME, Riek R, Britschgi M, Stahlberg H

eLife (2018) 7 [ Pubmed: 29969391 DOI: doi:10.7554/eLife.36402 ]

EMPIAR-10195
Related EMDB
EMD-4276
Cryo-EM structure of alpha-synuclein fibrils
Release date: July 5, 2018
Dataset size: 6.3 GB
Experiment type: EMDB

Guerrero-Ferreira R, Taylor NM, Mona D, Ringler P, Lauer ME, Riek R, Britschgi M, Stahlberg H

eLife (2018) 7 [ Pubmed: 29969391 DOI: 10.7554/elife.36402 ]

Image sets:
  • Aligned micrographs of alpha-synuclein 1-121 fibrils
Sort by: Download
Showing 1 - 7 of 7. Page 1 of 1
Display:
Statistics
×

Download



Preview 10 entries View All Download file

Filter By

Current Database

  • EMDB [5]
  • EMPIAR [2]

Current status

  • REL [7]

Sample type

  • Complex [5]
  • Protein [5]

Organism

  • Homo sapiens [5]

EM Method

  • Helical reconstruction [5]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [4]

Model molecular weight

  • 100-250 kDa [5]

Release Date

  • 2020 [1]
  • 2019 [4]
  • 2018 [2]

Author by name

  • Britschgi M [7]
  • Guerrero-ferreira R [7]
  • Lauer ME [7]
  • Mona D [7]
  • Riek R [7]
  • Ringler P [7]
  • Stahlberg H [7]
  • Taylor NM [7]
  • Arteni AA [5]
  • Bousset L [5]
  • Kumari P [5]
  • Makky A [5]
  • Meier BH [5]
  • Melki R [5]
  • Taylor NMI [5]
  • Verasdonck J [5]
  • Bockmann A [4]
  • Böckmann A [1]

Author by ORCID

  • Britschgi M [5]
  • Stahlberg H [5]
  • Guerrero-ferreira R [5]
  • Riek R [5]
  • Taylor NM [5]
  • Lauer ME [5]
  • Ringler P [5]
  • Arteni AA [4]
  • Bockmann A [4]
  • Bousset L [4]
  • Makky A [4]
  • Kumari P [4]
  • Meier BH [4]

Journal

  • ELIFE [7]
  • BIORXIV [2]

Software

  • RELION [5]
  • COOT [4]

Microscope

  • FEI TITAN KRIOS [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [5]

EMPIAR Experiment type

  • EMDB [2]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [1]
  • MICROGRAPHS - SINGLE FRAME [1]

External links

  • AlphaFold DB [5]
  • Complex Portal [5]
  • Gene Ontology [5]
  • InterPro [5]
  • PDB [5]
  • PDBe-Kb [5]
  • Pfam [5]
  • UniProt [5]
  • EMDB [2]
  • EMPIAR [2]