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author:"Kyriakis E"

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Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Protein [6]
  • Ligand [4]

Organism

  • Xenopus laevis [6]
  • Homo sapiens [6]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 3Å and < 4Å [6]

Model molecular weight

  • 250-500 kDa [6]

Release Date

  • 2026 [2]
  • 2025 [2]
  • 2022 [2]

Author by name

  • Dou Y [6]
  • Eldstrom J [6]
  • Fedida D [6]
  • Kyriakis E [6]
  • Van Petegem F [6]
  • Ataei F [4]
  • Maragliano L [4]
  • Molinarolo S [4]
  • Roscioni A [4]
  • Russo S [4]
  • Sastre D [4]
  • Chan M [2]
  • Sahakyan H [2]
  • Taddei A [2]
  • Tian M [2]
  • Willegems K [2]

Author by ORCID

  • Fedida D [4]
  • Eldstrom J [4]
  • Van Petegem F [4]
  • Sastre D [2]
  • Maragliano L [2]
  • Molinarolo S [2]
  • Kyriakis E [2]
  • Sahakyan H [2]
  • Roscioni A [2]

Journal

  • NAT COMMUN [4]
  • SCI ADV [2]

Software

  • CRYOSPARC [6]
  • CTFFIND [2]

Microscope

  • TFS KRIOS [4]
  • FEI TITAN KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • FEI FALCON IV 4K X 4K [5]
  • FEI FALCON III 4K X 4K [1]

External links

  • AlphaFold DB [6]
  • PDB [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • Gene Ontology [4]
  • InterPro [4]
  • ChEBI [2]
  • DrugBank [2]
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Showing 1 - 6 of 6. Page 1 of 1
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EMD-75305
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3D View
Xenopus KCNQ1 Intermediate State E1R/R2E in complex with UCL2077
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.95 Å
EM Method: Single-particle
Fitted PDBs: 10nk
Q-score: 0.299
Similar entry percentile: 21%

Kyriakis E, Roscioni A, Eldstrom J, Sastre D, Dou Y, Taddei A, Molinarolo S, Tian M, Maragliano L, Van Petegem F, Fedida D

Sci Adv (2026) [ ]

EMD-75306
Download Map
3D View
Xenopus KCNQ1 in complex with UCL2077
CryoEM
Release date: Sept. 2, 2026
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 10nl
Q-score: 0.3
Similar entry percentile: 17%

Kyriakis E, Roscioni A, Eldstrom J, Sastre D, Dou Y, Taddei A, Molinarolo S, Tian M, Maragliano L, Van Petegem F, Fedida D

Sci Adv (2026) [ ]

EMD-48725
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3D View
Structure of Xenopus KCNQ1-CaM in GDN
CryoEM
Release date: Oct. 15, 2025
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 9my3
Q-score: 0.479
Similar entry percentile: 68%

Kyriakis E, Sastre D, Eldstrom J, Roscioni A, Russo S, Ataei F, Dou Y, Chan M, Molinarolo S, Maragliano L, Van Petegem F, Fedida D

Nat Commun (2025) 16 pp. 8814-8814 [ DOI: doi:10.1038/s41467-025-64060-3 Pubmed: 41044058 ]

EMD-48726
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Structure of Xenopus KCNQ1 E150R/R221E -CaM with the VSD in the intermediate state
CryoEM
Release date: Oct. 15, 2025
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 9my4

Kyriakis E, Sastre D, Eldstrom J, Roscioni A, Russo S, Ataei F, Dou Y, Chan M, Molinarolo S, Maragliano L, Van Petegem F, Fedida D

Nat Commun (2025) 16 pp. 8814-8814 [ DOI: doi:10.1038/s41467-025-64060-3 Pubmed: 41044058 ]

EMD-25813
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Structure of Xenopus KCNQ1-CaM in complex with ML277
CryoEM
Release date: July 6, 2022
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7tci
Q-score: 0.399
Similar entry percentile: 55%

Willegems K, Eldstrom J, Kyriakis E, Ataei F, Sahakyan H, Dou Y, Russo S, Van Petegem F, Fedida D

Nat Commun (2022) 13 pp. 3760-3760 [ DOI: doi:10.1038/s41467-022-31526-7 Pubmed: 35768468 ]

EMD-25816
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3D View
Structure of Xenopus KCNQ1-CaM
CryoEM
Release date: July 6, 2022
Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 7tcp
Q-score: 0.464
Similar entry percentile: 84%

Willegems K, Eldstrom J, Kyriakis E, Ataei F, Sahakyan H, Dou Y, Russo S, Van Petegem F, Fedida D

Nat Commun (2022) 13 pp. 3760-3760 [ DOI: doi:10.1038/s41467-022-31526-7 Pubmed: 35768468 ]

Sort by: Download
Showing 1 - 6 of 6. Page 1 of 1
Display:
Statistics
×

Download


Preview 10 entries View All Download file

Filter By

Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Protein [6]
  • Ligand [4]

Organism

  • Xenopus laevis [6]
  • Homo sapiens [6]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 3Å and < 4Å [6]

Model molecular weight

  • 250-500 kDa [6]

Release Date

  • 2026 [2]
  • 2025 [2]
  • 2022 [2]

Author by name

  • Dou Y [6]
  • Eldstrom J [6]
  • Fedida D [6]
  • Kyriakis E [6]
  • Van Petegem F [6]
  • Ataei F [4]
  • Maragliano L [4]
  • Molinarolo S [4]
  • Roscioni A [4]
  • Russo S [4]
  • Sastre D [4]
  • Chan M [2]
  • Sahakyan H [2]
  • Taddei A [2]
  • Tian M [2]
  • Willegems K [2]

Author by ORCID

  • Fedida D [4]
  • Eldstrom J [4]
  • Van Petegem F [4]
  • Sastre D [2]
  • Maragliano L [2]
  • Molinarolo S [2]
  • Kyriakis E [2]
  • Sahakyan H [2]
  • Roscioni A [2]

Journal

  • NAT COMMUN [4]
  • SCI ADV [2]

Software

  • CRYOSPARC [6]
  • CTFFIND [2]

Microscope

  • TFS KRIOS [4]
  • FEI TITAN KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • FEI FALCON IV 4K X 4K [5]
  • FEI FALCON III 4K X 4K [1]

External links

  • AlphaFold DB [6]
  • PDB [6]
  • PDBe-Kb [6]
  • Pfam [6]
  • UniProt [6]
  • Gene Ontology [4]
  • InterPro [4]
  • ChEBI [2]
  • DrugBank [2]