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author:"Grassucci RA"

Filter By

Current Database

  • EMDB [103]

Current status

  • REL [103]

Sample type

  • Complex [100]
  • Protein [85]
  • Ligand [55]
  • Sample [22]
  • RNA [15]

Organism

  • Homo sapiens [54]
  • Oryctolagus cuniculus [30]
  • Escherichia coli [25]
  • Rattus norvegicus [15]
  • Mus musculus [8]
  • Caenorhabditis elegans [3]
  • Pestivirus c [2]
  • Cricket paralysis virus [2]
  • Escherichia coli [2]
  • Synthetic construct [1]
  • Saccharomyces cerevisiae [1]
  • Trypanosoma brucei [1]
  • Trypanosoma cruzi [1]
  • Canis lupus [1]
  • Equus caballus [1]

EM Method

  • Single-particle [102]
  • Subtomogram averaging [1]

Resolution

  • ≥ 2Å and < 3Å [7]
  • ≥ 3Å and < 4Å [28]
  • ≥ 4Å and < 5Å [27]
  • ≥ 5Å and < 6Å [2]
  • ≥ 6Å and < 8Å [11]
  • ≥ 8Å and < 12Å [15]
  • ≥ 12Å and < 16Å [5]
  • ≥ 16Å and < 20Å [5]
  • ≥ 20Å and < 30Å [2]

Model molecular weight

  • 50-100 kDa [3]
  • 100-250 kDa [8]
  • 250-500 kDa [19]
  • 500-1000 kDa [3]
  • 1-2 MDa [21]
  • 2-5 MDa [15]

Release Date

  • 2024 [18]
  • 2020 [3]
  • 2019 [7]
  • 2018 [2]
  • 2017 [15]
  • 2016 [37]
  • 2014 [1]
  • 2013 [5]
  • 2009 [1]
  • 2005 [2]
  • 2004 [6]
  • 2003 [5]
  • 2002 [1]

Author by name

  • Grassucci RA [103]
  • Frank J [99]
  • Clarke OB [44]
  • Fu Z [38]
  • Des Georges A [31]
  • Hendrickson WA [28]
  • Marks AR [26]
  • Zalk R [26]
  • Condon KJ [25]
  • Yuan Q [25]
  • Ehrenberg M [20]
  • Brouillette CG [18]
  • Cohen BM [18]
  • Hunt JF [18]
  • Jiang F [18]
  • Kappes JC [18]
  • Li Y [18]
  • Loughlin BJ [18]
  • Lukacs GL [18]
  • Menten ER [18]
  • Mezzell A [18]
  • Rich Z [18]
  • Singh S [18]
  • Sutton RB [18]
  • Urbatsch IL [18]
  • Veit G [18]
  • Vorobiev S [18]
  • Wang C [18]
  • Wang W [18]
  • Wetmore DR [18]
  • Wong K [18]
  • Xu H [18]
  • Yang Z [18]
  • Sobolevsky AI [17]
  • Twomey EC [17]
  • Yelshanskaya MV [17]
  • Sun M [16]
  • Chen B [15]
  • Kaledhonkar S [15]
  • Shah B [8]
  • Spahn CM [8]
  • Borg A [7]
  • Indrisiunaite G [7]
  • Sengupta J [7]
  • Valle M [6]
  • Hashem Y [5]
  • Linde J [5]
  • Rawat UB [5]
  • Vestergaard B [5]
  • Zavialov AV [5]
  • Zhang Y [5]
  • Hellen CUT [4]
  • Jan E [4]
  • Langlois R [4]
  • Liao HY [4]
  • Mcgoldrick LL [4]
  • Mulder A [4]
  • Pestova TV [4]
  • Saotome K [4]
  • Sarnow P [4]
  • Singh AK [4]
  • Agrawal RK [3]
  • Hellen CU [3]
  • Hu Z [3]
  • Li G [3]
  • Li H [3]
  • Li M [3]
  • Li S [3]
  • Li X [3]
  • Pan Y [3]
  • Ren Z [3]
  • Su D [3]
  • Yang J [3]
  • Zheng X [3]
  • Zhou M [3]
  • Beckmann R [2]
  • Dhote V [2]
  • Guo Y [2]
  • Liu Z [2]
  • Madison-antenucci S [2]
  • Qiu W [2]
  • Xu GG [2]
  • Aguilar JI [1]
  • Andersen GR [1]
  • Area-gomez E [1]
  • Bajaj C [1]
  • Ballesta JP [1]
  • Baxter WT [1]
  • Becker T [1]
  • Booth TM [1]
  • Burkhardt N [1]
  • Buss SN [1]
  • Carazo JM [1]
  • Carter SD [1]
  • Chan RB [1]
  • Chen EI [1]
  • Courel M [1]
  • Dhote A [1]
  • Di Paolo G [1]
  • Espina N [1]

Author by ORCID

  • Des Georges A [31]
  • Fu Z [20]
  • Twomey EC [17]
  • Sun M [16]
  • Hunt JF [11]
  • Rich Z [11]
  • Shah B [8]
  • Indrisiunaite G [7]
  • Valle M [6]
  • Zavialov AV [5]
  • Vestergaard B [5]
  • Sarnow P [4]
  • Frank J [3]
  • Zhou M [3]
  • Li G [3]
  • Yang J [3]
  • Su D [3]
  • Hu Z [3]
  • Guo Y [2]
  • Madison-antenucci S [2]
  • Jin A [1]
  • Jia Y [1]
  • Gabashvili IS [1]
  • Ren Y [1]
  • Tong L [1]
  • Liu Z [1]
  • Feng X [1]
  • Wei J [1]
  • Woolford JL [1]
  • Bajaj C [1]
  • Jorgensen R [1]
  • Svergun DI [1]
  • Nissen P [1]
  • Gomez-lorenzo MG [1]
  • Pool MR [1]
  • Mancia F [1]
  • Villa E [1]
  • Jiang H [1]

Journal

  • CELL [31]
  • NATURE [19]
  • TO BE PUBLISHED [18]
  • STRUCTURE [9]
  • NAT COMMUN [8]
  • PNAS [5]
  • NEURON [4]
  • SCIENCE [4]
  • NAT STRUCT MOL BIOL [3]
  • EMBO J [2]
  • J STRUCT BIOL [1]
  • NUCLEIC ACIDS RES [1]

Software

  • RELION [42]
  • SPIDER [10]
  • CTFFIND3 [7]
  • SPIDER/WEB [4]
  • CHIMERA [3]
  • CRYOSPARC [3]
  • O [3]
  • SPIDER, RELION [3]
  • MANUAL [2]
  • ETOMO/SERIAL, EM [1]
  • MDFF [1]

Microscope

  • FEI POLARA 300 [44]
  • FEI TITAN KRIOS [32]
  • FEI TECNAI F30 [14]
  • FEI TECNAI F20 [10]
  • FEI TECNAI 20 [1]
  • FEI/PHILIPS CM200FEG/ST [1]
  • FEI/PHILIPS EM420 [1]

Electron Source

  • FIELD EMISSION GUN [102]
  • LAB6 [1]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [63]
  • GATAN K3 BIOQUANTUM 6K X 4K [18]
  • KODAK SO-163 FILM [16]
  • GATAN ULTRASCAN 4000 4K X 4K [3]
  • FEI FALCON II 4K X 4K [1]
  • GATAN K2 4K X 4K [1]
  • TVIPS TEMCAM-F415 4K X 4K [1]

External links

  • PDB [103]
  • PDBe-Kb [78]
  • UniProt [78]
  • AlphaFold DB [77]
  • Gene Ontology [56]
  • InterPro [56]
  • Pfam [55]
  • ChEBI [49]
  • DrugBank [48]
  • ChEMBL [47]
  • Complex Portal [26]
  • CATH [1]
  • SCOP2 [1]
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Showing 1 - 10 of 103. Page 1 of 11
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EMD-41717
Download Map
3D View
N3Shifted Consensus Map - Mechanism of dual pharmacological correction and potentiation of human CFTR
CryoEM
Consensus map
Release date: Oct. 16, 2024
Resolution: 3.22 Å
EM Method: Single-particle

Wang C, Yang Z, Loughlin BJ, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Singh S, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

To Be Published

EMD-41719
Download Map
3D View
N3Shifted Local CORE1 Map - Mechanism of dual pharmacological correction and potentiation of human CFTR
Focused map
CryoEM
Release date: Oct. 16, 2024
Resolution: 3.57 Å
EM Method: Single-particle

Wang C, Yang Z, Loughlin BJ, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Singh S, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

To Be Published

EMD-41722
Download Map
3D View
N3Shifted Local ABC2 Map - Mechanism of dual pharmacological correction and potentiation of human CFTR
Focused map
CryoEM
Release date: Oct. 16, 2024
Resolution: 3.55 Å
EM Method: Single-particle

Wang C, Yang Z, Loughlin BJ, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Singh S, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

To Be Published

EMD-41723
Download Map
3D View
N3Shifted Local CORE2 Map - Mechanism of dual pharmacological correction and potentiation of human CFTR
CryoEM
Focused map
Release date: Oct. 16, 2024
Resolution: 3.43 Å
EM Method: Single-particle

Wang C, Yang Z, Loughlin BJ, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Singh S, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

To Be Published

EMD-41724
Download Map
3D View
N3 Shifted Local ABC2 Map - Mechanism of dual pharmacological correction and potentiation of human CFTR
CryoEM
Focused map
Release date: Oct. 16, 2024
Resolution: 3.4 Å
EM Method: Single-particle

Wang C, Yang Z, Loughlin BJ, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Singh S, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

To Be Published

EMD-41726
Download Map
3D View
N3Shifted Composite Map - Mechanism of dual pharmacological correction and potentiation of human CFTR
Composite map
CryoEM
Release date: Oct. 16, 2024
Resolution: 3.32 Å
EM Method: Single-particle

Wang C, Yang Z, Loughlin BJ, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Singh S, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

To Be Published

EMD-41895
Download Map
3D View
N3Occluded Local CORE1 Map - Mechanism of dual pharmacological correction and potentiation of human CFTR
CryoEM
Release date: Oct. 16, 2024
Resolution: 3.57 Å
EM Method: Single-particle

Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

To Be Published

EMD-41896
Download Map
3D View
N3Occluded Local ABC1 Map - Mechanism of dual pharmacological correction and potentiation of human CFTR
CryoEM
Release date: Oct. 16, 2024
Resolution: 3.59 Å
EM Method: Single-particle

Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

To Be Published

EMD-41898
Download Map
3D View
N3Occluded Local ABC2 Map - Mechanism of dual pharmacological correction and potentiation of human CFTR
CryoEM
Release date: Oct. 16, 2024
Resolution: 3.43 Å
EM Method: Single-particle

Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

To Be Published

EMD-41901
Download Map
3D View
N3Occluded Composite Map - Mechanism of dual pharmacological correction and potentiation of human CFTR
Composite map
CryoEM
Release date: Oct. 16, 2024
Resolution: 3.03 Å
EM Method: Single-particle

Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

To Be Published

Sort by: Download
Showing 1 - 10 of 103. Page 1 of 11
Display:
Statistics
×

Download


Preview 10 entries View All Download file

Filter By

Current Database

  • EMDB [103]

Current status

  • REL [103]

Sample type

  • Complex [100]
  • Protein [85]
  • Ligand [55]
  • Sample [22]
  • RNA [15]

Organism

  • Homo sapiens [54]
  • Oryctolagus cuniculus [30]
  • Escherichia coli [25]
  • Rattus norvegicus [15]
  • Mus musculus [8]
  • Caenorhabditis elegans [3]
  • Pestivirus c [2]
  • Cricket paralysis virus [2]
  • Escherichia coli [2]
  • Synthetic construct [1]
  • Saccharomyces cerevisiae [1]
  • Trypanosoma brucei [1]
  • Trypanosoma cruzi [1]
  • Canis lupus [1]
  • Equus caballus [1]

EM Method

  • Single-particle [102]
  • Subtomogram averaging [1]

Resolution

  • ≥ 2Å and < 3Å [7]
  • ≥ 3Å and < 4Å [28]
  • ≥ 4Å and < 5Å [27]
  • ≥ 5Å and < 6Å [2]
  • ≥ 6Å and < 8Å [11]
  • ≥ 8Å and < 12Å [15]
  • ≥ 12Å and < 16Å [5]
  • ≥ 16Å and < 20Å [5]
  • ≥ 20Å and < 30Å [2]

Model molecular weight

  • 50-100 kDa [3]
  • 100-250 kDa [8]
  • 250-500 kDa [19]
  • 500-1000 kDa [3]
  • 1-2 MDa [21]
  • 2-5 MDa [15]

Release Date

  • 2024 [18]
  • 2020 [3]
  • 2019 [7]
  • 2018 [2]
  • 2017 [15]
  • 2016 [37]
  • 2014 [1]
  • 2013 [5]
  • 2009 [1]
  • 2005 [2]
  • 2004 [6]
  • 2003 [5]
  • 2002 [1]

Author by name

  • Grassucci RA [103]
  • Frank J [99]
  • Clarke OB [44]
  • Fu Z [38]
  • Des Georges A [31]
  • Hendrickson WA [28]
  • Marks AR [26]
  • Zalk R [26]
  • Condon KJ [25]
  • Yuan Q [25]
  • Ehrenberg M [20]
  • Brouillette CG [18]
  • Cohen BM [18]
  • Hunt JF [18]
  • Jiang F [18]
  • Kappes JC [18]
  • Li Y [18]
  • Loughlin BJ [18]
  • Lukacs GL [18]
  • Menten ER [18]
  • Mezzell A [18]
  • Rich Z [18]
  • Singh S [18]
  • Sutton RB [18]
  • Urbatsch IL [18]
  • Veit G [18]
  • Vorobiev S [18]
  • Wang C [18]
  • Wang W [18]
  • Wetmore DR [18]
  • Wong K [18]
  • Xu H [18]
  • Yang Z [18]
  • Sobolevsky AI [17]
  • Twomey EC [17]
  • Yelshanskaya MV [17]
  • Sun M [16]
  • Chen B [15]
  • Kaledhonkar S [15]
  • Shah B [8]
  • Spahn CM [8]
  • Borg A [7]
  • Indrisiunaite G [7]
  • Sengupta J [7]
  • Valle M [6]
  • Hashem Y [5]
  • Linde J [5]
  • Rawat UB [5]
  • Vestergaard B [5]
  • Zavialov AV [5]
  • Zhang Y [5]
  • Hellen CUT [4]
  • Jan E [4]
  • Langlois R [4]
  • Liao HY [4]
  • Mcgoldrick LL [4]
  • Mulder A [4]
  • Pestova TV [4]
  • Saotome K [4]
  • Sarnow P [4]
  • Singh AK [4]
  • Agrawal RK [3]
  • Hellen CU [3]
  • Hu Z [3]
  • Li G [3]
  • Li H [3]
  • Li M [3]
  • Li S [3]
  • Li X [3]
  • Pan Y [3]
  • Ren Z [3]
  • Su D [3]
  • Yang J [3]
  • Zheng X [3]
  • Zhou M [3]
  • Beckmann R [2]
  • Dhote V [2]
  • Guo Y [2]
  • Liu Z [2]
  • Madison-antenucci S [2]
  • Qiu W [2]
  • Xu GG [2]
  • Aguilar JI [1]
  • Andersen GR [1]
  • Area-gomez E [1]
  • Bajaj C [1]
  • Ballesta JP [1]
  • Baxter WT [1]
  • Becker T [1]
  • Booth TM [1]
  • Burkhardt N [1]
  • Buss SN [1]
  • Carazo JM [1]
  • Carter SD [1]
  • Chan RB [1]
  • Chen EI [1]
  • Courel M [1]
  • Dhote A [1]
  • Di Paolo G [1]
  • Espina N [1]

Author by ORCID

  • Des Georges A [31]
  • Fu Z [20]
  • Twomey EC [17]
  • Sun M [16]
  • Hunt JF [11]
  • Rich Z [11]
  • Shah B [8]
  • Indrisiunaite G [7]
  • Valle M [6]
  • Zavialov AV [5]
  • Vestergaard B [5]
  • Sarnow P [4]
  • Frank J [3]
  • Zhou M [3]
  • Li G [3]
  • Yang J [3]
  • Su D [3]
  • Hu Z [3]
  • Guo Y [2]
  • Madison-antenucci S [2]
  • Jin A [1]
  • Jia Y [1]
  • Gabashvili IS [1]
  • Ren Y [1]
  • Tong L [1]
  • Liu Z [1]
  • Feng X [1]
  • Wei J [1]
  • Woolford JL [1]
  • Bajaj C [1]
  • Jorgensen R [1]
  • Svergun DI [1]
  • Nissen P [1]
  • Gomez-lorenzo MG [1]
  • Pool MR [1]
  • Mancia F [1]
  • Villa E [1]
  • Jiang H [1]

Journal

  • CELL [31]
  • NATURE [19]
  • TO BE PUBLISHED [18]
  • STRUCTURE [9]
  • NAT COMMUN [8]
  • PNAS [5]
  • NEURON [4]
  • SCIENCE [4]
  • NAT STRUCT MOL BIOL [3]
  • EMBO J [2]
  • J STRUCT BIOL [1]
  • NUCLEIC ACIDS RES [1]

Software

  • RELION [42]
  • SPIDER [10]
  • CTFFIND3 [7]
  • SPIDER/WEB [4]
  • CHIMERA [3]
  • CRYOSPARC [3]
  • O [3]
  • SPIDER, RELION [3]
  • MANUAL [2]
  • ETOMO/SERIAL, EM [1]
  • MDFF [1]

Microscope

  • FEI POLARA 300 [44]
  • FEI TITAN KRIOS [32]
  • FEI TECNAI F30 [14]
  • FEI TECNAI F20 [10]
  • FEI TECNAI 20 [1]
  • FEI/PHILIPS CM200FEG/ST [1]
  • FEI/PHILIPS EM420 [1]

Electron Source

  • FIELD EMISSION GUN [102]
  • LAB6 [1]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [63]
  • GATAN K3 BIOQUANTUM 6K X 4K [18]
  • KODAK SO-163 FILM [16]
  • GATAN ULTRASCAN 4000 4K X 4K [3]
  • FEI FALCON II 4K X 4K [1]
  • GATAN K2 4K X 4K [1]
  • TVIPS TEMCAM-F415 4K X 4K [1]

External links

  • PDB [103]
  • PDBe-Kb [78]
  • UniProt [78]
  • AlphaFold DB [77]
  • Gene Ontology [56]
  • InterPro [56]
  • Pfam [55]
  • ChEBI [49]
  • DrugBank [48]
  • ChEMBL [47]
  • Complex Portal [26]
  • CATH [1]
  • SCOP2 [1]