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author:"Cruz Leon S"

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Current Database

  • EMDB [61]
  • EMPIAR [2]

Current status

  • REL [63]

Sample type

  • Complex [38]
  • Cell [17]
  • Virus [6]
  • Protein [5]

Organism

  • Dictyostelium discoideum [36]
  • Homo sapiens [19]
  • Human immunodeficiency virus 1 [6]

EM Method

  • Subtomogram averaging [53]
  • Single-particle [5]
  • Tomography [3]

Resolution

  • ≥ 3Å and < 4Å [3]
  • ≥ 4Å and < 5Å [3]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]
  • ≥ 8Å and < 12Å [1]
  • ≥ 12Å and < 16Å [1]
  • ≥ 20Å and < 30Å [16]
  • ≥ 30Å [32]

Model molecular weight

  • 5-10 MDa [2]

Release Date

  • 2026 [5]
  • 2025 [22]
  • 2024 [36]

Author by name

  • Cruz-leon S [61]
  • Hummer G [61]
  • Beck M [58]
  • Kreysing JP [57]
  • Turonova B [56]
  • Obarska-kosinska A [53]
  • Hoffmann PC [34]
  • Andino-frydman E [33]
  • Cernikova L [33]
  • Kim H [33]
  • Kosinski J [33]
  • Margiotta E [33]
  • Welsch S [24]
  • Heidari M [20]
  • Kofinger J [20]
  • Krausslich HG [20]
  • Laketa V [20]
  • Rohleder L [20]
  • Zila V [20]
  • Aupic J [5]
  • Cassetta A [5]
  • Cotugno D [5]
  • Covaceuszach S [5]
  • D Ercole C [5]
  • Durand A [5]
  • Gangupam B [5]
  • Lapenta F [5]
  • Magistrato A [5]
  • Marechal N [5]
  • Marrancone S [5]
  • Moussaoui D [5]
  • Palacio-rodriguez K [5]
  • Parra C [5]
  • Tomaino G [5]
  • Tortora P [5]
  • De Marco A [5]
  • Tuijtel MW [3]
  • Kreysing J [1]
  • Turoňová B [1]

Author by ORCID

  • Hummer G [61]
  • Kreysing JP [56]
  • Obarska-kosinska A [53]
  • Kosinski J [33]
  • Hoffmann PC [33]
  • Andino-frydman E [33]
  • Cruz-leon S [8]
  • Tortora P [5]
  • Tomaino G [5]
  • Aupic J [5]
  • De Marco A [5]
  • Parra C [5]
  • Magistrato A [5]
  • Cassetta A [5]
  • Durand A [5]
  • Lapenta F [5]
  • Palacio-rodriguez K [5]
  • Cotugno D [5]
  • D'ercole C [5]
  • Tuijtel MW [3]
  • Turonova B [3]
  • Welsch S [3]
  • Beck M [3]

Journal

  • MOL CELL [33]
  • CELL [21]
  • NAT COMMUN [6]
  • BIORXIV [4]
  • SCI ADV [3]

Software

  • NOVASTA [20]
  • RELION [5]
  • CRYOSPARC [4]
  • WARP [3]

Microscope

  • TFS KRIOS [33]
  • FEI TITAN KRIOS [28]

Electron Source

  • FIELD EMISSION GUN [61]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [38]
  • FEI FALCON IV 4K X 4K [23]

EMPIAR Experiment type

  • EMDB [2]

EMPIAR Image category

  • TILT SERIES [2]
  • RECONSTRUCTED VOLUMES [1]

External links

  • PDB [61]
  • EMPIAR [24]
  • AlphaFold DB [5]
  • Complex Portal [5]
  • PDBe-Kb [5]
  • UniProt [5]
  • EMDB [2]
  • Pfam [2]
  • Gene Ontology [1]
Sort by: Download
Showing 1 - 10 of 63. Page 1 of 7
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EMD-53423
Download Map
3D View
Human vault protein - committed conformation
CryoEM
Release date: May 6, 2026
Resolution: 4.45 Å
EM Method: Single-particle
Fitted PDBs: 9qwq
Q-score: 0.223

Lapenta F, Palacio-Rodriguez K, Cruz-Leon S, Marrancone S, Aupic J, Marechal N, Durand A, Moussaoui D, Covaceuszach S, Gangupam B, D'Ercole C, Parra C, Cotugno D, Tomaino G, Tortora P, de Marco A, Cassetta A, Magistrato A, Hummer G

Nat Commun (2026) [ Pubmed: 42069735 DOI: doi:10.1038/s41467-026-72674-4 ]

EMD-53415
Download Map
3D View
Human vault protein - primed conformation
CryoEM
Release date: April 29, 2026
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 9qw9

Lapenta F, Palacio-Rodriguez K, Cruz-Leon S, Marrancone S, Aupic J, Marechal N, Durand A, Moussaoui D, Covaceuszach S, Gangupam B, D'Ercole C, Parra C, Cotugno D, Tomaino G, Tortora P, de Marco A, Cassetta A, Magistrato A, Hummer G

Nat Commun (2026) [ Pubmed: 42069735 DOI: doi:10.1038/s41467-026-72674-4 ]

EMD-53438
Download Map
3D View
Human vault protein - local refinement of the waist - primed conformation
CryoEM
Release date: April 29, 2026
Resolution: 3.53 Å
EM Method: Single-particle

Lapenta F, Palacio-Rodriguez K, Cruz-Leon S, Marrancone S, Aupic J, Marechal N, Durand A, Moussaoui D, Covaceuszach S, Gangupam B, D'Ercole C, Parra C, Cotugno D, Tomaino G, Tortora P, de Marco A, Cassetta A, Magistrato A, Hummer G

Nat Commun (2026) [ Pubmed: 42069735 DOI: doi:10.1038/s41467-026-72674-4 ]

EMD-53439
Download Map
3D View
Human vault protein - local refinement of the waist - committed conformation
CryoEM
Release date: April 29, 2026
Resolution: 6.06 Å
EM Method: Single-particle

Lapenta F, Palacio-Rodriguez K, Cruz-Leon S, Marrancone S, Aupic J, Marechal N, Durand A, Moussaoui D, Covaceuszach S, Gangupam B, D'Ercole C, Parra C, Cotugno D, Tomaino G, Tortora P, de Marco A, Cassetta A, Magistrato A, Hummer G

Nat Commun (2026) [ Pubmed: 42069735 DOI: doi:10.1038/s41467-026-72674-4 ]

EMD-53440
Download Map
3D View
39-mer half of the human vault protein
CryoEM
Release date: April 29, 2026
Resolution: 9.89 Å
EM Method: Single-particle

Lapenta F, Palacio-Rodriguez K, Cruz-Leon S, Marrancone S, Aupic J, Marechal N, Durand A, Moussaoui D, Covaceuszach S, Gangupam B, D'Ercole C, Parra C, Cotugno D, Tomaino G, Tortora P, de Marco A, Cassetta A, Magistrato A, Hummer G

Nat Commun (2026) [ Pubmed: 42069735 DOI: doi:10.1038/s41467-026-72674-4 ]

EMPIAR-12454
Related EMDB
EMD-51535 EMD-51532 EMD-51531 EMD-51536 EMD-51533 EMD-51628 EMD-51626 EMD-51534 EMD-51629 EMD-51627 EMD-51630 EMD-51632 EMD-51631
Cryo-ET dataset of FIB-milled HIV-1 infected human monocyte-derived macrophages
Release date: April 3, 2025
Dataset size: 560.6 GB
Experiment type: EMDB

Kreysing JP, Heidari M, Zila V, Cruz-Leon S, Obarska-Kosinska A, Laketa V, Rohleder L, Welsch S, Köfinger J, Turoňová B, Hummer G, Kräuslich HG, Beck M

Cell (2025) 188 pp. 930-943.e21 [ Pubmed: 39826544 DOI: 10.1016/j.cell.2024.12.008 ]

Image sets:
  • Raw tilt-series of human macrophage cells infected with HIV-1
  • Tilt cleaned, dose-filtered tilt-series of human macrophage cells infected with HIV-1
  • Reconstructed tomograms of human macrophage cells infected with HIV-1 (4x binning and filtered with sirt-like filter)
EMPIAR-11845
Related EMDB
EMD-19137
Cryo-ET of Dictyostelium discoideum in HL5 medium (control condition)
Release date: Feb. 24, 2025
Dataset size: 386.5 GB
Experiment type: EMDB

Hoffmann PC, Kim H, Obarska-Kosinska A, Kreysing JP, Andino-Frydman E, Cruz-Leon S, Cernikova L, Kosinski J, Turonova B, Hummer G, Beck M

To Be Published

Image sets:
  • Raw tilt series of D. dicoideum cells (control condition) - frame aligned
EMD-51531
Download Map
3D View
Raw data
EMPIAR-12454
HIV-1 CA hexamer from capsids inside virions FIB-lamella data of HIV infected macrophages
CryoEM
Release date: Jan. 15, 2025
Resolution: 30.1 Å
EM Method: Subtomogram averaging

Kreysing JP, Heidari M, Zila V, Cruz-Leon S, Obarska-Kosinska A, Laketa V, Rohleder L, Welsch S, Kofinger J, Turonova B, Hummer G, Krausslich HG, Beck M

Cell (2025) 188 pp. 930-943.e21 [ Pubmed: 39826544 DOI: doi:10.1016/j.cell.2024.12.008 ]

EMD-51532
Download Map
3D View
Raw data
EMPIAR-12454
HIV-1 CA hexamer from cytoplasmic capsids FIB-lamella data of HIV infected macrophages
CryoEM
Release date: Jan. 15, 2025
Resolution: 27.7 Å
EM Method: Subtomogram averaging

Kreysing JP, Heidari M, Zila V, Cruz-Leon S, Obarska-Kosinska A, Laketa V, Rohleder L, Welsch S, Kofinger J, Turonova B, Hummer G, Krausslich HG, Beck M

Cell (2025) 188 pp. 930-943.e21 [ Pubmed: 39826544 DOI: doi:10.1016/j.cell.2024.12.008 ]

EMD-51533
Download Map
3D View
Raw data
EMPIAR-12454
HIV-1 CA hexamer from capsids inside NPCs FIB-lamella data of HIV infected macrophages
CryoEM
Release date: Jan. 15, 2025
Resolution: 33.0 Å
EM Method: Subtomogram averaging

Kreysing JP, Heidari M, Zila V, Cruz-Leon S, Obarska-Kosinska A, Laketa V, Rohleder L, Welsch S, Kofinger J, Turonova B, Hummer G, Krausslich HG, Beck M

Cell (2025) 188 pp. 930-943.e21 [ Pubmed: 39826544 DOI: doi:10.1016/j.cell.2024.12.008 ]

Sort by: Download
Showing 1 - 10 of 63. Page 1 of 7
Display:
Statistics
×

Download












































Preview first 10
Download

Filter By

Current Database

  • EMDB [61]
  • EMPIAR [2]

Current status

  • REL [63]

Sample type

  • Complex [38]
  • Cell [17]
  • Virus [6]
  • Protein [5]

Organism

  • Dictyostelium discoideum [36]
  • Homo sapiens [19]
  • Human immunodeficiency virus 1 [6]

EM Method

  • Subtomogram averaging [53]
  • Single-particle [5]
  • Tomography [3]

Resolution

  • ≥ 3Å and < 4Å [3]
  • ≥ 4Å and < 5Å [3]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]
  • ≥ 8Å and < 12Å [1]
  • ≥ 12Å and < 16Å [1]
  • ≥ 20Å and < 30Å [16]
  • ≥ 30Å [32]

Model molecular weight

  • 5-10 MDa [2]

Release Date

  • 2026 [5]
  • 2025 [22]
  • 2024 [36]

Author by name

  • Cruz-leon S [61]
  • Hummer G [61]
  • Beck M [58]
  • Kreysing JP [57]
  • Turonova B [56]
  • Obarska-kosinska A [53]
  • Hoffmann PC [34]
  • Andino-frydman E [33]
  • Cernikova L [33]
  • Kim H [33]
  • Kosinski J [33]
  • Margiotta E [33]
  • Welsch S [24]
  • Heidari M [20]
  • Kofinger J [20]
  • Krausslich HG [20]
  • Laketa V [20]
  • Rohleder L [20]
  • Zila V [20]
  • Aupic J [5]
  • Cassetta A [5]
  • Cotugno D [5]
  • Covaceuszach S [5]
  • D Ercole C [5]
  • Durand A [5]
  • Gangupam B [5]
  • Lapenta F [5]
  • Magistrato A [5]
  • Marechal N [5]
  • Marrancone S [5]
  • Moussaoui D [5]
  • Palacio-rodriguez K [5]
  • Parra C [5]
  • Tomaino G [5]
  • Tortora P [5]
  • De Marco A [5]
  • Tuijtel MW [3]
  • Kreysing J [1]
  • Turoňová B [1]

Author by ORCID

  • Hummer G [61]
  • Kreysing JP [56]
  • Obarska-kosinska A [53]
  • Kosinski J [33]
  • Hoffmann PC [33]
  • Andino-frydman E [33]
  • Cruz-leon S [8]
  • Tortora P [5]
  • Tomaino G [5]
  • Aupic J [5]
  • De Marco A [5]
  • Parra C [5]
  • Magistrato A [5]
  • Cassetta A [5]
  • Durand A [5]
  • Lapenta F [5]
  • Palacio-rodriguez K [5]
  • Cotugno D [5]
  • D'ercole C [5]
  • Tuijtel MW [3]
  • Turonova B [3]
  • Welsch S [3]
  • Beck M [3]

Journal

  • MOL CELL [33]
  • CELL [21]
  • NAT COMMUN [6]
  • BIORXIV [4]
  • SCI ADV [3]

Software

  • NOVASTA [20]
  • RELION [5]
  • CRYOSPARC [4]
  • WARP [3]

Microscope

  • TFS KRIOS [33]
  • FEI TITAN KRIOS [28]

Electron Source

  • FIELD EMISSION GUN [61]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [38]
  • FEI FALCON IV 4K X 4K [23]

EMPIAR Experiment type

  • EMDB [2]

EMPIAR Image category

  • TILT SERIES [2]
  • RECONSTRUCTED VOLUMES [1]

External links

  • PDB [61]
  • EMPIAR [24]
  • AlphaFold DB [5]
  • Complex Portal [5]
  • PDBe-Kb [5]
  • UniProt [5]
  • EMDB [2]
  • Pfam [2]
  • Gene Ontology [1]