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author:"Cai K"

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Current Database

  • EMDB [49]
  • EMPIAR [2]

Current status

  • REL [51]

Sample type

  • Complex [37]
  • Protein [37]
  • Ligand [22]
  • Cell [6]
  • Cellular component [4]
  • Virus [2]

Organism

  • Homo sapiens [22]
  • Caulobacter vibrioides [8]
  • Neospora caninum [6]
  • Synthetic construct [5]
  • Chlamydomonas reinhardtii [4]
  • Drosophila melanogaster [4]
  • Danio rerio [3]
  • Lama glama [3]
  • Human respiratory syncytial virus [2]
  • Severe acute respiratory syndrome coronavirus [2]
  • Mus musculus [1]

EM Method

  • Single-particle [35]
  • Subtomogram averaging [11]
  • Helical reconstruction [2]
  • Tomography [1]

Resolution

  • ≥ 2Å and < 3Å [10]
  • ≥ 3Å and < 4Å [23]
  • ≥ 4Å and < 5Å [2]
  • ≥ 6Å and < 8Å [1]
  • ≥ 8Å and < 12Å [1]
  • ≥ 16Å and < 20Å [2]
  • ≥ 20Å and < 30Å [5]
  • ≥ 30Å [5]

Model molecular weight

  • 100-250 kDa [22]
  • 250-500 kDa [6]
  • 500-1000 kDa [2]
  • 1-2 MDa [7]

Release Date

  • 2025 [10]
  • 2024 [27]
  • 2023 [10]
  • 2021 [4]

Author by name

  • Cai K [51]
  • Sun JP [20]
  • Yu X [20]
  • Zhang C [20]
  • Li Z [19]
  • Cai BY [17]
  • Huang SM [17]
  • Jia YL [17]
  • Liu L [17]
  • Tie L [17]
  • Wang JL [17]
  • Wang MW [17]
  • Wen X [17]
  • Xiao P [17]
  • Xiong MY [17]
  • Yang BX [17]
  • Yang F [17]
  • Yang Z [17]
  • Huang S [14]
  • Yi F [14]
  • Sun J [13]
  • Parrell D [12]
  • Sanchez JC [12]
  • Wright ER [12]
  • Yang JE [12]
  • Huang ZZ [11]
  • Li M [11]
  • Sun Y [11]
  • Weng CH [11]
  • Xie YH [11]
  • Zhang H [11]
  • Zhang MH [11]
  • Baumgardt JK [10]
  • Montemayor EJ [10]
  • Nicastro D [10]
  • Ploscariu NT [10]
  • Sibert B [10]
  • Kong W [9]
  • Cao S [8]
  • Wang X [8]
  • Bai XC [7]
  • Choi E [7]
  • Hall C [7]
  • Ng M [7]
  • Cong X [6]
  • Du Y [6]
  • Gan S [6]
  • Guan YF [6]
  • Gui L [6]
  • Guo SC [6]
  • He QT [6]
  • Li S [6]
  • Li Y [6]
  • Liu Z [6]
  • Mu J [6]
  • O Shaughnessy Wj [6]
  • Qu CX [6]
  • Reese ML [6]
  • Reetz E [6]
  • Xie Y [6]
  • Xue C [6]
  • Zhang X [6]
  • Zhang M [5]
  • Zhang Z [5]
  • Cheng X [4]
  • Hossain MA [4]
  • Hou Y [4]
  • Jinpeng S [4]
  • Lei L [4]
  • Mengyao X [4]
  • Phan N [4]
  • Sheng C [4]
  • Shenming H [4]
  • Tatar M [4]
  • Wade JD [4]
  • Witman GB [4]
  • Yamamoto RR [4]
  • Zhao L [4]
  • Zhao Y [4]
  • Accili D [3]
  • An W [3]
  • Baker D [3]
  • Cardoso S [3]
  • Chowhan R [3]
  • Coventry B [3]
  • Gao J [3]
  • Gao M [3]
  • Gerben S [3]
  • Guo L [3]
  • Guo LL [3]
  • Guo Y [3]
  • Han J [3]
  • Hon M [3]
  • Hung A [3]
  • Jiang C [3]
  • Jiang CT [3]
  • Lee DS [3]
  • Li F [3]
  • Li J [3]
  • Liao YC [3]

Author by ORCID

  • Sun JP [20]
  • Jia YL [17]
  • Liu L [17]
  • Xiao P [17]
  • Yi F [14]
  • Cai K [14]
  • Yu X [14]
  • Zhang H [11]
  • Nicastro D [10]
  • Sanchez JC [10]
  • Wright ER [10]
  • Zhang C [9]
  • Bai XC [7]
  • Wang MW [6]
  • Yang Z [6]
  • Du Y [6]
  • Reese ML [6]
  • He QT [6]
  • Gui L [6]
  • Yang F [6]
  • Liu Z [6]
  • Zhang X [6]
  • O'shaughnessy WJ [6]
  • Qu CX [6]
  • Xue C [6]
  • Gan S [6]
  • Tie L [6]
  • Xiong MY [6]
  • Zhao Y [4]
  • Hall C [4]
  • Ng M [4]
  • Wade JD [4]
  • Witman GB [4]
  • Phan N [4]
  • Cheng X [4]
  • Tatar M [4]
  • Choi E [4]
  • Lin H [3]
  • Kong W [3]
  • Guo L [3]
  • Wang T [3]
  • Guo Y [3]
  • Zhang Z [3]
  • Jiang C [3]
  • Huang S [3]
  • Lin J [3]
  • Qin C [3]
  • Ma C [3]
  • Zhang D [3]
  • Han J [3]
  • Wang X [3]
  • Ye C [3]
  • Li F [3]
  • Lv L [3]
  • Zhang M [3]
  • Cai K [3]
  • Yan H [2]
  • Lan K [2]
  • Yang JE [2]
  • Pappas V [2]
  • Cai K [2]
  • Cao S [2]
  • Kim JY [2]
  • Chen Y [2]

Journal

  • NAT COMMUN [21]
  • TO BE PUBLISHED [8]
  • PNAS [6]
  • J CELL SCI [4]
  • MOL CELL [3]
  • SCIENCE [3]
  • BIORXIV [2]
  • NAT METHODS [2]
  • SIGNAL TRANSDUCT TARGET THER [2]

Software

  • CRYOSPARC [7]
  • RELION [7]
  • ETOMO [4]
  • GCTF [3]
  • IMOD [2]
  • 3DMOD [1]

Microscope

  • FEI TITAN KRIOS [28]
  • TFS KRIOS [18]
  • JEOL CRYO ARM 300 [2]
  • TFS GLACIOS [1]

Electron Source

  • FIELD EMISSION GUN [32]
  • OTHER [17]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [21]
  • GATAN K3 6K X 4K [14]
  • FEI FALCON II 4K X 4K [11]
  • FEI FALCON IV 4K X 4K [1]
  • GATAN K2 SUMMIT 4K X 4K [1]
  • GATAN K3 BIOCONTINUUM 6K X 4K [1]

EMPIAR Experiment type

  • EMDB [2]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [2]

External links

  • PDB [37]
  • UniProt [37]
  • AlphaFold DB [36]
  • PDBe-Kb [33]
  • Pfam [33]
  • Gene Ontology [26]
  • InterPro [26]
  • ChEBI [14]
  • ChEMBL [13]
  • Complex Portal [5]
  • DrugBank [5]
  • EMDB [2]
  • EMPIAR [2]
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Showing 1 - 10 of 51. Page 1 of 6
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EMD-47031
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3D View
Insulin receptor bound with de novo designed agonist called RF-405 .
Release date: Oct. 1, 2025
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 9dn6
Q-score: 0.326

Wang X, Cardoso S, Cai K, Venkatesh P, Hung A, Ng M, Hall C, Coventry B, Lee DS, Chowhan R, Gerben S, Li J, An W, Hon M, Gao M, Liao YC, Accili D, Choi E, Bai XC, Baker D

Mol Cell (2025) 85 pp. 4064- [ DOI: doi:10.1016/j.molcel.2025.09.020 Pubmed: 41086805 ]

EMD-47041
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3D View
Insulin receptor bound with de novo designed agonist called S2-F1-S1
Release date: Oct. 1, 2025
Resolution: 8.2 Å
EM Method: Single-particle
Fitted PDBs: 9dni
Q-score: 0.163

Wang X, Cardoso S, Cai K, Venkatesh P, Hung A, Ng M, Hall C, Coventry B, Lee DS, Chowhan R, Gerben S, Li J, An W, Hon M, Gao M, Liao YC, Accili D, Choi E, Bai XC, Baker D

Mol Cell (2025) 85 pp. 4064- [ DOI: doi:10.1016/j.molcel.2025.09.020 Pubmed: 41086805 ]

EMD-47043
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3D View
Insulin receptor in complex with both insulin and de novo designed site-2 binder S2B .
Release date: Oct. 1, 2025
Resolution: 6.1 Å
EM Method: Single-particle
Fitted PDBs: 9dnn
Q-score: 0.215

Wang X, Cardoso S, Cai K, Venkatesh P, Hung A, Ng M, Hall C, Coventry B, Lee DS, Chowhan R, Gerben S, Li J, An W, Hon M, Gao M, Liao YC, Accili D, Choi E, Bai XC, Baker D

Mol Cell (2025) 85 pp. 4064- [ DOI: doi:10.1016/j.molcel.2025.09.020 Pubmed: 41086805 ]

EMD-47967
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Cryo-EM structure of Drosophila melanogaster insulin receptor dmIR bound with one DILP1, asymmetric conformation
Release date: Oct. 1, 2025
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 9ef1
Q-score: 0.283

Cai K, Ng M, Yamamoto RR, Hossain MA, Hall C, Wade JD, Tatar M, Choi E, Bai XC

Nat Commun (2025) 16 pp. 9504-9504 [ Pubmed: 41152236 DOI: doi:10.1038/s41467-025-64586-6 ]

EMD-47969
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3D View
Cryo-EM structure of Drosophila melanogaster insulin receptor dmIR bound with two DILP1, symmetric conformation
Release date: Oct. 1, 2025
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 9ef4
Q-score: 0.338

Cai K, Ng M, Yamamoto RR, Hossain MA, Hall C, Wade JD, Tatar M, Choi E, Bai XC

Nat Commun (2025) 16 pp. 9504-9504 [ Pubmed: 41152236 DOI: doi:10.1038/s41467-025-64586-6 ]

EMD-47970
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3D View
Cryo-EM structure of Drosophila melanogaster insulin receptor dmIR bound with one DILP2, asymmetric conformation
Release date: Oct. 1, 2025
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 9ef5
Q-score: 0.413

Cai K, Ng M, Yamamoto RR, Hossain MA, Hall C, Wade JD, Tatar M, Choi E, Bai XC

Nat Commun (2025) 16 pp. 9504-9504 [ Pubmed: 41152236 DOI: doi:10.1038/s41467-025-64586-6 ]

EMD-47971
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3D View
Cryo-EM structure of Drosophila melanogaster insulin receptor dmIR bound with three DILP5, asymmetric conformation
Release date: Oct. 1, 2025
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9ef9
Q-score: 0.418

Cai K, Ng M, Yamamoto RR, Hossain MA, Hall C, Wade JD, Tatar M, Choi E, Bai XC

Nat Commun (2025) 16 pp. 9504-9504 [ Pubmed: 41152236 DOI: doi:10.1038/s41467-025-64586-6 ]

EMD-61484
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3D View
Cryo-EM structure of the C18:0 ceramide-bound FPR2-Gi complex
Release date: March 19, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9jhj
Q-score: 0.538

Lin H, Ma C, Cai K, Guo L, Wang X, Lv L, Zhang C, Lin J, Zhang D, Ye C, Wang T, Huang S, Han J, Zhang Z, Gao J, Zhang M, Pu Z, Li F, Guo Y, Zhou X, Qin C, Yi F, Yu X, Kong W, Jiang C, Sun JP

Science (2025) 388 pp. eado4188-eado4188 [ DOI: doi:10.1126/science.ado4188 Pubmed: 40080544 ]

EMD-38964
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3D View
Cryo-EM structure of the C16:0 ceramide-bound FPR2-Gi complex
Release date: Feb. 5, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8y62
Q-score: 0.491

Lin H, Ma C, Cai K, Guo L, Wang X, Lv L, Zhang C, Lin J, Zhang D, Ye C, Wang T, Huang S, Han J, Zhang Z, Gao J, Zhang M, Pu Z, Li F, Guo Y, Zhou X, Qin C, Yi F, Yu X, Kong W, Jiang C, Sun JP

Science (2025) 388 pp. eado4188-eado4188 [ DOI: doi:10.1126/science.ado4188 Pubmed: 40080544 ]

EMD-38965
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3D View
Cryo-EM structure of the C20:0 ceramide-bound FPR2-Gi complex
Release date: Feb. 5, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8y63
Q-score: 0.454

Lin H, Ma C, Cai K, Guo L, Wang X, Lv L, Zhang C, Lin J, Zhang D, Ye C, Wang T, Huang S, Han J, Zhang Z, Gao J, Zhang M, Pu Z, Li F, Guo Y, Zhou X, Qin C, Yi F, Yu X, Kong W, Jiang C, Sun JP

Science (2025) 388 pp. eado4188-eado4188 [ DOI: doi:10.1126/science.ado4188 Pubmed: 40080544 ]

Sort by: Download
Showing 1 - 10 of 51. Page 1 of 6
Display:
Statistics
×

Download












































Preview first 10
Download

Filter By

Current Database

  • EMDB [49]
  • EMPIAR [2]

Current status

  • REL [51]

Sample type

  • Complex [37]
  • Protein [37]
  • Ligand [22]
  • Cell [6]
  • Cellular component [4]
  • Virus [2]

Organism

  • Homo sapiens [22]
  • Caulobacter vibrioides [8]
  • Neospora caninum [6]
  • Synthetic construct [5]
  • Chlamydomonas reinhardtii [4]
  • Drosophila melanogaster [4]
  • Danio rerio [3]
  • Lama glama [3]
  • Human respiratory syncytial virus [2]
  • Severe acute respiratory syndrome coronavirus [2]
  • Mus musculus [1]

EM Method

  • Single-particle [35]
  • Subtomogram averaging [11]
  • Helical reconstruction [2]
  • Tomography [1]

Resolution

  • ≥ 2Å and < 3Å [10]
  • ≥ 3Å and < 4Å [23]
  • ≥ 4Å and < 5Å [2]
  • ≥ 6Å and < 8Å [1]
  • ≥ 8Å and < 12Å [1]
  • ≥ 16Å and < 20Å [2]
  • ≥ 20Å and < 30Å [5]
  • ≥ 30Å [5]

Model molecular weight

  • 100-250 kDa [22]
  • 250-500 kDa [6]
  • 500-1000 kDa [2]
  • 1-2 MDa [7]

Release Date

  • 2025 [10]
  • 2024 [27]
  • 2023 [10]
  • 2021 [4]

Author by name

  • Cai K [51]
  • Sun JP [20]
  • Yu X [20]
  • Zhang C [20]
  • Li Z [19]
  • Cai BY [17]
  • Huang SM [17]
  • Jia YL [17]
  • Liu L [17]
  • Tie L [17]
  • Wang JL [17]
  • Wang MW [17]
  • Wen X [17]
  • Xiao P [17]
  • Xiong MY [17]
  • Yang BX [17]
  • Yang F [17]
  • Yang Z [17]
  • Huang S [14]
  • Yi F [14]
  • Sun J [13]
  • Parrell D [12]
  • Sanchez JC [12]
  • Wright ER [12]
  • Yang JE [12]
  • Huang ZZ [11]
  • Li M [11]
  • Sun Y [11]
  • Weng CH [11]
  • Xie YH [11]
  • Zhang H [11]
  • Zhang MH [11]
  • Baumgardt JK [10]
  • Montemayor EJ [10]
  • Nicastro D [10]
  • Ploscariu NT [10]
  • Sibert B [10]
  • Kong W [9]
  • Cao S [8]
  • Wang X [8]
  • Bai XC [7]
  • Choi E [7]
  • Hall C [7]
  • Ng M [7]
  • Cong X [6]
  • Du Y [6]
  • Gan S [6]
  • Guan YF [6]
  • Gui L [6]
  • Guo SC [6]
  • He QT [6]
  • Li S [6]
  • Li Y [6]
  • Liu Z [6]
  • Mu J [6]
  • O Shaughnessy Wj [6]
  • Qu CX [6]
  • Reese ML [6]
  • Reetz E [6]
  • Xie Y [6]
  • Xue C [6]
  • Zhang X [6]
  • Zhang M [5]
  • Zhang Z [5]
  • Cheng X [4]
  • Hossain MA [4]
  • Hou Y [4]
  • Jinpeng S [4]
  • Lei L [4]
  • Mengyao X [4]
  • Phan N [4]
  • Sheng C [4]
  • Shenming H [4]
  • Tatar M [4]
  • Wade JD [4]
  • Witman GB [4]
  • Yamamoto RR [4]
  • Zhao L [4]
  • Zhao Y [4]
  • Accili D [3]
  • An W [3]
  • Baker D [3]
  • Cardoso S [3]
  • Chowhan R [3]
  • Coventry B [3]
  • Gao J [3]
  • Gao M [3]
  • Gerben S [3]
  • Guo L [3]
  • Guo LL [3]
  • Guo Y [3]
  • Han J [3]
  • Hon M [3]
  • Hung A [3]
  • Jiang C [3]
  • Jiang CT [3]
  • Lee DS [3]
  • Li F [3]
  • Li J [3]
  • Liao YC [3]

Author by ORCID

  • Sun JP [20]
  • Jia YL [17]
  • Liu L [17]
  • Xiao P [17]
  • Yi F [14]
  • Cai K [14]
  • Yu X [14]
  • Zhang H [11]
  • Nicastro D [10]
  • Sanchez JC [10]
  • Wright ER [10]
  • Zhang C [9]
  • Bai XC [7]
  • Wang MW [6]
  • Yang Z [6]
  • Du Y [6]
  • Reese ML [6]
  • He QT [6]
  • Gui L [6]
  • Yang F [6]
  • Liu Z [6]
  • Zhang X [6]
  • O'shaughnessy WJ [6]
  • Qu CX [6]
  • Xue C [6]
  • Gan S [6]
  • Tie L [6]
  • Xiong MY [6]
  • Zhao Y [4]
  • Hall C [4]
  • Ng M [4]
  • Wade JD [4]
  • Witman GB [4]
  • Phan N [4]
  • Cheng X [4]
  • Tatar M [4]
  • Choi E [4]
  • Lin H [3]
  • Kong W [3]
  • Guo L [3]
  • Wang T [3]
  • Guo Y [3]
  • Zhang Z [3]
  • Jiang C [3]
  • Huang S [3]
  • Lin J [3]
  • Qin C [3]
  • Ma C [3]
  • Zhang D [3]
  • Han J [3]
  • Wang X [3]
  • Ye C [3]
  • Li F [3]
  • Lv L [3]
  • Zhang M [3]
  • Cai K [3]
  • Yan H [2]
  • Lan K [2]
  • Yang JE [2]
  • Pappas V [2]
  • Cai K [2]
  • Cao S [2]
  • Kim JY [2]
  • Chen Y [2]

Journal

  • NAT COMMUN [21]
  • TO BE PUBLISHED [8]
  • PNAS [6]
  • J CELL SCI [4]
  • MOL CELL [3]
  • SCIENCE [3]
  • BIORXIV [2]
  • NAT METHODS [2]
  • SIGNAL TRANSDUCT TARGET THER [2]

Software

  • CRYOSPARC [7]
  • RELION [7]
  • ETOMO [4]
  • GCTF [3]
  • IMOD [2]
  • 3DMOD [1]

Microscope

  • FEI TITAN KRIOS [28]
  • TFS KRIOS [18]
  • JEOL CRYO ARM 300 [2]
  • TFS GLACIOS [1]

Electron Source

  • FIELD EMISSION GUN [32]
  • OTHER [17]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [21]
  • GATAN K3 6K X 4K [14]
  • FEI FALCON II 4K X 4K [11]
  • FEI FALCON IV 4K X 4K [1]
  • GATAN K2 SUMMIT 4K X 4K [1]
  • GATAN K3 BIOCONTINUUM 6K X 4K [1]

EMPIAR Experiment type

  • EMDB [2]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [2]

External links

  • PDB [37]
  • UniProt [37]
  • AlphaFold DB [36]
  • PDBe-Kb [33]
  • Pfam [33]
  • Gene Ontology [26]
  • InterPro [26]
  • ChEBI [14]
  • ChEMBL [13]
  • Complex Portal [5]
  • DrugBank [5]
  • EMDB [2]
  • EMPIAR [2]