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Target Report Card

Target Name and Classification

Target ID CHEMBL6125
Preferred Name Histidine kinase
Synonyms AHK3 | Arabidopsis histidine kinase 3 | AtHK3 | Histidine kinase 3 | ORE12 | Protein AUTHENTIC HIS-KINASE 3 | Protein ORESARA 12
Organism Arabidopsis thaliana
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Histidine kinase 3 SINGLE PROTEIN Q9C5U1

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0000155 (phosphorelay sensor kinase activity)
GO:0004673 (protein histidine kinase activity)
GO:0004721 (phosphoprotein phosphatase activity)
GO:0005515 (protein binding)
GO:0009884 (cytokinin receptor activity)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0016772 (transferase activity, transferring phosphorus-containing groups)
GO:0043424 (protein histidine kinase binding)
GO Biological Process GO:0000160 (phosphorelay signal transduction system)
GO:0006970 (response to osmotic stress)
GO:0007165 (signal transduction)
GO:0007275 (multicellular organism development)
GO:0009409 (response to cold)
GO:0009414 (response to water deprivation)
GO:0009651 (response to salt stress)
GO:0009736 (cytokinin-activated signaling pathway)
GO:0009909 (regulation of flower development)
GO:0010029 (regulation of seed germination)
GO:0010087 (phloem or xylem histogenesis)
GO:0010150 (leaf senescence)
GO:0010271 (regulation of chlorophyll catabolic process)
GO:0016036 (cellular response to phosphate starvation)
GO:0016310 (phosphorylation)
GO:0018106 (peptidyl-histidine phosphorylation)
GO:0023014 (signal transduction by protein phosphorylation)
GO:0034757 (negative regulation of iron ion transport)
GO:0042742 (defense response to bacterium)
GO:0048509 (regulation of meristem development)
GO:0048831 (regulation of shoot system development)
GO:0070417 (cellular response to cold)
GO:0071215 (cellular response to abscisic acid stimulus)
GO:0071329 (cellular response to sucrose stimulus)
GO:0080117 (secondary growth)

Target Cross References - Protein

canSAR Q9C5U1
IntAct Q9C5U1
UniProt Q9C5U1 Q9FZK3

Target Cross References - Domain

InterPro IPR000836 (PRibTrfase_dom.)
IPR001789 (Sig_transdc_resp-reg_receiver.)
IPR003594 (HATPase_C.)
IPR003661 (HisK_dim/P.)
IPR004358 (Sig_transdc_His_kin-like_C.)
IPR005467 (His_kinase_dom.)
IPR006189 (CHASE_dom.)
IPR011006 (CheY-like_superfamily.)
Pfam PF00072 (Response_reg)
PF00512 (HisKA)
PF02518 (HATPase_c)
PF03924 (CHASE)