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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL6013
Target Type SINGLE PROTEIN
Preferred Name Ceramide glucosyltransferase
Synonyms Ceramide glucosyltransferase | GCS | GLCT-1 | Glucosylceramide synthase | UDP-glucose ceramide glucosyltransferase | UDP-glucose:N-acylsphingosine D-glucosyltransferase | Ugcg
Organism Mus musculus
Species Group No
Protein Target Classification
  • enzyme > transferase

Target Components

Component Description Relationship Accession
Ceramide glucosyltransferase SINGLE PROTEIN O88693

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0000139 (Golgi membrane)
GO:0005794 (Golgi apparatus)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0008120 (ceramide glucosyltransferase activity)
GO:0016740 (transferase activity)
GO:0016757 (transferase activity, transferring glycosyl groups)
GO:0102769 (dihydroceramide glucosyltransferase activity)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006665 (sphingolipid metabolic process)
GO:0006679 (glucosylceramide biosynthetic process)
GO:1903955 (positive regulation of protein targeting to mitochondrion)

Target Cross References - Protein

canSAR O88693
Reactome R-MMU-1660662 (Glycosphingolipid metabolism.)
UniProt A2AN90 O88693

Target Cross References - Domain

InterPro IPR025993 (Ceramide_glucosylTrfase.)
IPR029044 (Nucleotide-diphossugar_trans.)
Pfam PF13506 (Glyco_transf_21)
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