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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL6002
Preferred Name Cell division cycle 2-like protein kinase 6
Synonyms CDC2-related protein kinase 6 | CDC2L6 | CDK11 | CDK19 | Cell division cycle 2-like protein kinase 6 | Cell division protein kinase 19 | Cyclin-dependent kinase 11 | Cyclin-dependent kinase 19 | Death-preventing kinase | KIAA1028
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > cmgc protein kinase group > cmgc protein kinase cdk family > cmgc protein kinase cdk8 subfamily

Target Components

Component Description Relationship Accession
Cyclin-dependent kinase 19 SINGLE PROTEIN Q9BWU1

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3559691 Cyclin-dependent kinase PROTEIN FAMILY
CHEMBL3883323 Cyclin-C/Cyclin-dependent kinase 19 PROTEIN COMPLEX
CHEMBL3885556 Cyclin-dependent kinase 8/19 PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000155111
Ensembl ENSG00000155111
GO Cellular Component GO:0005634 (nucleus)
GO:0005829 (cytosol)
GO:0016592 (mediator complex)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0019899 (enzyme binding)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0007346 (regulation of mitotic cell cycle)
GO:0016310 (phosphorylation)
GO:0043065 (positive regulation of apoptotic process)
GO:0050729 (positive regulation of inflammatory response)
GO:0071222 (cellular response to lipopolysaccharide)

Target Cross References - Protein

Human Protein Atlas ENSG00000155111
IntAct Q9BWU1
Guide to Pharmacology 1972
Open Targets ENSG00000155111
PharmGKB PA165617767
Pharos Q9BWU1 (Tchem)
Reactome R-HSA-1989781 (PPARA activates gene expression.)
R-HSA-381340 (Transcriptional regulation of white adipocyte differentiation.)
UniProt Q5JQZ7 Q5JR00 Q8TC78 Q9BWU1 Q9UPX2

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)