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ChEMBL

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Target Report Card

Target Name and Classification

Target ID CHEMBL5910
Target Type SINGLE PROTEIN
Preferred Name Aurora kinase A-interacting protein
Synonyms 28S ribosomal protein S38, mitochondrial | AIP | AKIP | AURKA-interacting protein | AURKAIP1 | Aurora kinase A-interacting protein | MRP-S38 | MRPS38 | Mitochondrial small ribosomal subunit protein mS38
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Aurora kinase A-interacting protein SINGLE PROTEIN Q9NWT8

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000175756
Ensembl ENSG00000175756
GO Cellular Component GO:0005634 (nucleus)
GO:0005654 (nucleoplasm)
GO:0005739 (mitochondrion)
GO:0005743 (mitochondrial inner membrane)
GO:0043231 (intracellular membrane-bounded organelle)
GO Molecular Function GO:0005515 (protein binding)
GO Biological Process GO:0045839 (negative regulation of mitotic nuclear division)
GO:0045862 (positive regulation of proteolysis)
GO:0070125 (mitochondrial translational elongation)
GO:0070126 (mitochondrial translational termination)

Target Cross References - Protein

canSAR Q9NWT8
Human Protein Atlas ENSG00000175756
IntAct Q9NWT8
Open Targets ENSG00000175756
PharmGKB PA142672568
Reactome R-HSA-5368286 (Mitochondrial translation initiation.)
R-HSA-5389840 (Mitochondrial translation elongation.)
R-HSA-5419276 (Mitochondrial translation termination.)
UniProt Q5TA36 Q8TBD3 Q9NWT8

Target Cross References - Domain

InterPro IPR013177 (DUF1713.)
Pfam PF08213 (DUF1713)
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