ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL5851
Target Type SINGLE PROTEIN
Preferred Name Baculoviral IAP repeat-containing protein 8
Synonyms BIRC8 | Baculoviral IAP repeat-containing protein 8 | IAP-like protein 2 | ILP-2 | ILP2 | Inhibitor of apoptosis-like protein 2 | Testis-specific inhibitor of apoptosis
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Baculoviral IAP repeat-containing protein 8 SINGLE PROTEIN Q96P09

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000163098
Ensembl ENSG00000163098
GO Cellular Component GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO:0005876 (spindle microtubule)
GO Molecular Function GO:0004842 (ubiquitin-protein transferase activity)
GO:0008270 (zinc ion binding)
GO:0043027 (cysteine-type endopeptidase inhibitor activity involved in apoptotic process)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006915 (apoptotic process)
GO:0016567 (protein ubiquitination)
GO:0090263 (positive regulation of canonical Wnt signaling pathway)
GO:0090307 (mitotic spindle assembly)
GO:1990001 (inhibition of cysteine-type endopeptidase activity involved in apoptotic process)

Target Cross References - Protein

Human Protein Atlas ENSG00000163098
IntAct Q96P09
Open Targets ENSG00000163098
PharmGKB PA25365
UniProt Q6IPY1 Q96P09 Q96RW5

Target Cross References - Domain

InterPro IPR001370 (BIR_rpt.)
IPR001841 (Znf_RING.)
Pfam PF00653 (BIR)

Target Cross References - Structure

PDBe 1XB0 1XB1
CREDO 1XB0 1XB1
spacer
spacer