ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL5771
Target Type SINGLE PROTEIN
Preferred Name ALK tyrosine kinase receptor
Synonyms ALK tyrosine kinase receptor | Alk | Anaplastic lymphoma kinase | CD_antigen=CD246
Organism Mus musculus
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > tk protein kinase group > tyrosine protein kinase alk family

Target Components

Component Description Relationship Accession
ALK tyrosine kinase receptor SINGLE PROTEIN P97793

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0030424 (axon)
GO:0043234 (protein complex)
GO:0044297 (cell body)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004713 (protein tyrosine kinase activity)
GO:0004714 (transmembrane receptor protein tyrosine kinase activity)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0042802 (identical protein binding)
GO Biological Process GO:0000187 (activation of MAPK activity)
GO:0006468 (protein phosphorylation)
GO:0007165 (signal transduction)
GO:0007169 (transmembrane receptor protein tyrosine kinase signaling pathway)
GO:0007399 (nervous system development)
GO:0016310 (phosphorylation)
GO:0018108 (peptidyl-tyrosine phosphorylation)
GO:0046777 (protein autophosphorylation)
GO:0048666 (neuron development)

Target Cross References - Protein

UniProt E9QKV3 P97793

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR000998 (MAM_dom.)
IPR001245 (Ser-Thr/Tyr_kinase_cat_dom.)
IPR002011 (Tyr_kinase_rcpt_2_CS.)
IPR002172 (LDrepeatLR_classA_rpt.)
IPR008266 (Tyr_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR013320 (ConA-like_dom.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR020635 (Tyr_kinase_cat_dom.)
IPR026830 (ALK.)
Pfam PF00629 (MAM)
PF07714 (Pkinase_Tyr)
spacer
spacer