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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5743
Target Type SINGLE PROTEIN
Preferred Name Type-1 angiotensin II receptor
Synonyms AGTR1 | AT1 | Angiotensin II type-1 receptor | Type-1 angiotensin II receptor
Organism Sus scrofa
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > peptide receptor (family a gpcr) > short peptide receptor (family a gpcr) > angiotensin receptor

Target Components

Component Description Relationship Accession
Type-1 angiotensin II receptor SINGLE PROTEIN P30555

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004945 (angiotensin type II receptor activity)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0019229 (regulation of vasoconstriction)
GO:0038166 (angiotensin-activated signaling pathway)

Target Cross References - Protein

canSAR P30555
IntAct P30555
Reactome R-SSC-375276 (Peptide ligand-binding receptors.)
R-SSC-416476 (G alpha (q) signalling events.)
R-SSC-8856825 (Cargo recognition for clathrin-mediated endocytosis.)
R-SSC-8856828 (Clathrin-mediated endocytosis.)
UniProt P30555

Target Cross References - Domain

InterPro IPR000190 (ATII_AT1_rcpt.)
IPR000248 (ATII_rcpt.)
IPR000276 (GPCR_Rhodpsn.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
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