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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5726
Target Type SINGLE PROTEIN
Preferred Name Elongation of very long chain fatty acids protein 6
Synonyms 3-keto acyl-CoA synthase Elovl6 | ELOVL FA elongase 6 | ELOVL fatty acid elongase 6 | Elongation of very long chain fatty acids protein 6 | Elovl6 | Fatty acyl-CoA elongase | Lce | Long chain fatty acid elongase | Masr | Myelin-associated SUR4 protein | Synonyms=Face | Very long chain 3-ketoacyl-CoA synthase 6 | Very long chain 3-oxoacyl-CoA synthase 6
Organism Mus musculus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Elongation of very long chain fatty acids protein 6 SINGLE PROTEIN Q920L5

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0030176 (integral component of endoplasmic reticulum membrane)
GO Molecular Function GO:0009922 (fatty acid elongase activity)
GO:0016740 (transferase activity)
GO:0016747 (transferase activity, transferring acyl groups other than amino-acyl groups)
GO:0102336 (3-oxo-arachidoyl-CoA synthase activity)
GO:0102337 (3-oxo-cerotoyl-CoA synthase activity)
GO:0102338 (3-oxo-lignoceronyl-CoA synthase activity)
GO:0102756 (very-long-chain 3-ketoacyl-CoA synthase activity)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006631 (fatty acid metabolic process)
GO:0006633 (fatty acid biosynthetic process)
GO:0019367 (fatty acid elongation, saturated fatty acid)
GO:0030148 (sphingolipid biosynthetic process)
GO:0030497 (fatty acid elongation)
GO:0034625 (fatty acid elongation, monounsaturated fatty acid)
GO:0034626 (fatty acid elongation, polyunsaturated fatty acid)
GO:0042759 (long-chain fatty acid biosynthetic process)
GO:0042761 (very long-chain fatty acid biosynthetic process)

Target Cross References - Protein

canSAR Q920L5
Reactome R-MMU-75876 (Synthesis of very long-chain fatty acyl-CoAs.)
UniProt Q8CE45 Q920L5

Target Cross References - Domain

InterPro IPR002076 (ELO_fam.)
IPR030457 (ELO_CS.)
IPR033675 (ELOVL6.)
Pfam PF01151 (ELO)
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