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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5550
Target Type SINGLE PROTEIN
Preferred Name Chaperone activity of bc1 complex-like, mitochondrial
Synonyms ADCK3 | Atypical kinase COQ8A, mitochondrial | CABC1 | COQ8A | Chaperone activity of bc1 complex-like | Chaperone-ABC1-like | Coenzyme Q protein 8A | aarF domain-containing protein kinase 3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Atypical kinase COQ8A, mitochondrial SINGLE PROTEIN Q8NI60

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000163050
Ensembl ENSG00000163050
GO Cellular Component GO:0005739 (mitochondrion)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0043531 (ADP binding)
GO Biological Process GO:0006744 (ubiquinone biosynthetic process)
GO:0016310 (phosphorylation)
Wikipedia CABC1

Target Cross References - Protein

canSAR Q8NI60
CGD Coenzyme Q10 deficiency; Progressive cerebellar ataxia and atrophy; Spinocerebellar ataxia 9
Human Protein Atlas ENSG00000163050
IntAct Q8NI60
Guide to Pharmacology 1927
Open Targets ENSG00000163050
PharmGKB PA25999
Pharos Q8NI60 (Tbio)
UniProt Q5T7A5 Q63HK0 Q8NCJ6 Q8NI60 Q9HBQ1 Q9NQ67

Target Cross References - Domain

InterPro IPR004147 (UbiB_dom.)
IPR011009 (Kinase-like_dom.)
Pfam PF03109 (ABC1)

Target Cross References - Structure

PDBe 4PED 5I35
CREDO 4PED 5I35
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