ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL5547
Target Type SINGLE PROTEIN
Preferred Name Ankyrin repeat and protein kinase domain-containing protein 1
Synonyms ANKK1 | Ankyrin repeat and protein kinase domain-containing protein 1 | PKK2 | Protein kinase PKK2 | SGK288 | SgK288 | Sugen kinase 288 | X-kinase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > tkl protein kinase group > tkl protein kinase ripk family

Target Components

Component Description Relationship Accession
Ankyrin repeat and protein kinase domain-containing protein 1 SINGLE PROTEIN Q8NFD2

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000170209
Ensembl ENSG00000170209
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
Wikipedia ANKK1

Target Cross References - Protein

canSAR Q8NFD2
Human Protein Atlas ENSG00000170209
IntAct Q8NFD2
Guide to Pharmacology 1932
Open Targets ENSG00000170209
PharmGKB PA134872551
Pharos Q8NFD2 (Tbio)
UniProt Q8NFD2

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR001245 (Ser-Thr/Tyr_kinase_cat_dom.)
IPR002110 (Ankyrin_rpt.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR020683 (Ankyrin_rpt-contain_dom.)
Pfam PF07714 (Pkinase_Tyr)
PF12796 (Ank_2)
spacer
spacer