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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5525
Target Type SINGLE PROTEIN
Preferred Name 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase
Synonyms 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | Cholestenol Delta-isomerase | D8-D7 sterol isomerase | Delta(8)-Delta(7) sterol isomerase | EBP | Emopamil-binding protein
Organism Cavia porcellus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase SINGLE PROTEIN Q60490

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005634 (nucleus)
GO:0005635 (nuclear envelope)
GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0031410 (cytoplasmic vesicle)
GO Molecular Function GO:0000247 (C-8 sterol isomerase activity)
GO:0004769 (steroid delta-isomerase activity)
GO:0016853 (isomerase activity)
GO:0047750 (cholestenol delta-isomerase activity)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006694 (steroid biosynthetic process)
GO:0006695 (cholesterol biosynthetic process)
GO:0008202 (steroid metabolic process)
GO:0008203 (cholesterol metabolic process)
GO:0016125 (sterol metabolic process)
GO:0016126 (sterol biosynthetic process)
GO:0030097 (hemopoiesis)

Target Cross References - Protein

canSAR Q60490
UniProt Q60490 Q9QV23

Target Cross References - Domain

InterPro IPR007905 (EBP.)
IPR033118 (EXPERA.)
Pfam PF05241 (EBP)
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