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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5520
Target Type SINGLE PROTEIN
Preferred Name Casein kinase I isoform alpha-like
Synonyms CK1 | CKI-alpha-like | CSNK1A1L | Casein kinase I isoform alpha-like
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > ck1 protein kinase group > ck1 protein kinase ck1 family > ck1 protein kinase ck1-a

Target Components

Component Description Relationship Accession
Casein kinase I isoform alpha-like SINGLE PROTEIN Q8N752

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000180138
Ensembl ENSG00000180138
GO Cellular Component GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0006909 (phagocytosis)
GO:0008360 (regulation of cell shape)
GO:0016055 (Wnt signaling pathway)
GO:0016310 (phosphorylation)
GO:0018105 (peptidyl-serine phosphorylation)

Target Cross References - Protein

canSAR Q8N752
Human Protein Atlas ENSG00000180138
IntAct Q8N752
Guide to Pharmacology 1996
Open Targets ENSG00000180138
PharmGKB PA134917108
Pharos Q8N752 (Tdark)
UniProt Q5T2N2 Q8N752

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)
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