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Target Report Card

Target Name and Classification

Target ID CHEMBL5519
Target Type SINGLE PROTEIN
Preferred Name Serine/threonine-protein kinase DCLK2
Synonyms CL2 | CLICK-II | CLICK2 | CaMK-like CREB regulatory kinase 2 | DCAMKL2 | DCDC3B | DCK2 | DCLK2 | Doublecortin domain-containing protein 3B | Doublecortin-like and CAM kinase-like 2 | Doublecortin-like kinase 2 | Serine/threonine-protein kinase DCLK2
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > camk protein kinase group > camk protein kinase dcamk1 family

Target Components

Component Description Relationship Accession
Serine/threonine-protein kinase DCLK2 SINGLE PROTEIN Q8N568

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000170390
Ensembl ENSG00000170390
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005856 (cytoskeleton)
GO:0005874 (microtubule)
GO:0015630 (microtubule cytoskeleton)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0000226 (microtubule cytoskeleton organization)
GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
GO:0018105 (peptidyl-serine phosphorylation)
GO:0018107 (peptidyl-threonine phosphorylation)
GO:0021766 (hippocampus development)
GO:0021860 (pyramidal neuron development)
GO:0030182 (neuron differentiation)
GO:0035556 (intracellular signal transduction)
GO:1900181 (negative regulation of protein localization to nucleus)

Target Cross References - Protein

Human Protein Atlas ENSG00000170390
IntAct Q8N568
Guide to Pharmacology 2006
Open Targets ENSG00000170390
PharmGKB PA162383366
Pharos Q8N568 (Tchem)
UniProt C9J5Q9 Q59GC8 Q8N399 Q8N568

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR003533 (Doublecortin_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR036572 (Doublecortin_dom_sf.)
Pfam PF00069 (Pkinase)
PF03607 (DCX)
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