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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5436
Target Type SINGLE PROTEIN
Preferred Name Squalene epoxidase
Synonyms Squalene epoxidase | Synonyms=SQLE {ECO:0000313|EMBL:BAI48103.1 | sqle
Organism Sus scrofa
Species Group No
Protein Target Classification
  • enzyme > oxidoreductase

Target Components

Component Description Relationship Accession
Squalene epoxidase SINGLE PROTEIN A7L861

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004506 (squalene monooxygenase activity)
GO:0050660 (flavin adenine dinucleotide binding)
GO Biological Process GO:0008203 (cholesterol metabolic process)
GO:0016126 (sterol biosynthetic process)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

canSAR A7L861
Reactome R-SSC-191273 (Cholesterol biosynthesis.)
UniProt A7L861

Target Cross References - Domain

InterPro IPR013698 (Squalene_epoxidase.)
IPR036188 (FAD/NAD-bd_sf.)
Pfam PF08491 (SE)
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