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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5426
Target Type SINGLE PROTEIN
Preferred Name Myosin light chain kinase family member 4
Synonyms MYLK4 | Myosin light chain kinase family member 4 | SGK085 | SgK085 | Sugen kinase 85
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > camk protein kinase group > camk protein kinase mlck family

Target Components

Component Description Relationship Accession
Myosin light chain kinase family member 4 SINGLE PROTEIN Q86YV6

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000145949
Ensembl ENSG00000145949
GO Cellular Component GO:0005622 (intracellular)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0004687 (myosin light chain kinase activity)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
GO:0018105 (peptidyl-serine phosphorylation)
GO:0018107 (peptidyl-threonine phosphorylation)
GO:0035556 (intracellular signal transduction)

Target Cross References - Protein

canSAR Q86YV6
Human Protein Atlas ENSG00000145949
IntAct Q86YV6
Guide to Pharmacology 2111
Open Targets ENSG00000145949
PharmGKB PA162396406
Pharos Q86YV6 (Tchem)
UniProt A2RUC0 Q5TAW2 Q86YV6

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)

Target Cross References - Structure

PDBe 2X4F
CREDO 2X4F
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