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Target Report Card

Target Name and Classification

Target ID CHEMBL5415
Preferred Name Serine/threonine-protein kinase SRPK3
Synonyms MSSK-1 | MSSK1 | Muscle-specific serine kinase 1 | SR-protein-specific kinase 3 | SRPK3 | SRSF protein kinase 3 | STK23 | Serine/arginine-rich protein-specific kinase 3 | Serine/threonine-protein kinase 23
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > cmgc protein kinase group > cmgc protein kinase srpk family

Target Components

Component Description Relationship Accession
SRSF protein kinase 3 SINGLE PROTEIN Q9UPE1

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000184343
Ensembl ENSG00000184343
GO Cellular Component GO:0005575 (cellular_component)
GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0000245 (spliceosomal complex assembly)
GO:0006468 (protein phosphorylation)
GO:0007275 (multicellular organism development)
GO:0007517 (muscle organ development)
GO:0007519 (skeletal muscle tissue development)
GO:0016310 (phosphorylation)
GO:0030154 (cell differentiation)
GO:0035556 (intracellular signal transduction)
GO:0050684 (regulation of mRNA processing)
GO:0060537 (muscle tissue development)

Target Cross References - Protein

Human Protein Atlas ENSG00000184343
IntAct Q9UPE1
Guide to Pharmacology 2210
Open Targets ENSG00000184343
PharmGKB PA162404805
Pharos Q9UPE1 (Tchem)
UniProt Q13583 Q4F970 Q562F5 Q9UM62 Q9UPE1

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)