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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5407
Target Type SINGLE PROTEIN
Preferred Name Serine/threonine-protein kinase PIM3
Synonyms PIM3 | Serine/threonine-protein kinase pim-3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > camk protein kinase group > camk protein kinase pim family

Target Components

Component Description Relationship Accession
Serine/threonine-protein kinase pim-3 SINGLE PROTEIN Q86V86

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3559682 Serine/threonine-protein kinase PIM PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000198355
Ensembl ENSG00000198355
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0006915 (apoptotic process)
GO:0007049 (cell cycle)
GO:0007346 (regulation of mitotic cell cycle)
GO:0016310 (phosphorylation)
GO:0043066 (negative regulation of apoptotic process)
GO:0046777 (protein autophosphorylation)
GO:0061179 (negative regulation of insulin secretion involved in cellular response to glucose stimulus)

Target Cross References - Protein

canSAR Q86V86
Human Protein Atlas ENSG00000198355
IntAct Q86V86
Guide to Pharmacology 2160
Open Targets ENSG00000198355
PharmGKB PA134980758
Pharos Q86V86 (Tchem)
UniProt A5D8X8 A8K7J0 B1B0P0 Q68BM2 Q86V86

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017348 (PIM1/2/3.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)
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