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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5359
Target Type SINGLE PROTEIN
Preferred Name Isocitrate lyase
Synonyms ICL | ICL1 | Isocitrase | Isocitratase | Isocitrate lyase | MICA | Methylisocitrate lyase | Threo-D(S)-isocitrate glyoxylate-lyase
Organism Candida albicans
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Isocitrate lyase SINGLE PROTEIN Q9P8Q7

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005777 (peroxisome)
GO:0009514 (glyoxysome)
GO Molecular Function GO:0003824 (catalytic activity)
GO:0004451 (isocitrate lyase activity)
GO:0016829 (lyase activity)
GO:0046421 (methylisocitrate lyase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006097 (glyoxylate cycle)
GO:0006099 (tricarboxylic acid cycle)
GO:0008152 (metabolic process)
GO:0019752 (carboxylic acid metabolic process)

Target Cross References - Protein

canSAR Q9P8Q7
UniProt Q9P8Q7

Target Cross References - Domain

InterPro IPR006254 (Isocitrate_lyase.)
IPR015813 (Pyrv/PenolPyrv_Kinase-like_dom.)
IPR018523 (Isocitrate_lyase_ph_CS.)
Pfam PF00463 (ICL)
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