ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL5354
Target Type SINGLE PROTEIN
Preferred Name Aldehyde dehydrogenase, cytosolic 1
Synonyms ALDH class 1 | ALDH-E1 | ALHDII | Aldehyde dehydrogenase family 1 member A7 | Aldehyde dehydrogenase phenobarbital-inducible | Aldehyde dehydrogenase, cytosolic 1 | Aldh-pb | Aldh1 | Aldh1a4 | Aldh1a7
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Aldehyde dehydrogenase, cytosolic 1 SINGLE PROTEIN P13601

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0004028 (3-chloroallyl aldehyde dehydrogenase activity)
GO:0004029 (aldehyde dehydrogenase (NAD) activity)
GO:0016491 (oxidoreductase activity)
GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)
GO:0018479 (benzaldehyde dehydrogenase (NAD+) activity)
GO:0042802 (identical protein binding)
GO Biological Process GO:0006068 (ethanol catabolic process)
GO:0008152 (metabolic process)
GO:0035106 (operant conditioning)
GO:0051289 (protein homotetramerization)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

canSAR P13601
UniProt P13601

Target Cross References - Domain

InterPro IPR015590 (Aldehyde_DH_dom.)
IPR016160 (Ald_DH_CS_CYS.)
IPR016161 (Ald_DH/histidinol_DH.)
IPR016162 (Ald_DH_N.)
IPR016163 (Ald_DH_C.)
IPR029510 (Ald_DH_CS_GLU.)
Pfam PF00171 (Aldedh)
spacer
spacer