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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5316
Preferred Name Serine/threonine-protein kinase PCTAIRE-3
Synonyms CDK18 | Cell division protein kinase 18 | Cyclin-dependent kinase 18 | PCTAIRE-motif protein kinase 3 | PCTAIRE3 | PCTK3 | Serine/threonine-protein kinase PCTAIRE-3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > cmgc protein kinase group > cmgc protein kinase cdk family > cmgc protein kinase pctaire

Target Components

Component Description Relationship Accession
Cyclin-dependent kinase 18 SINGLE PROTEIN Q07002

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3559691 Cyclin-dependent kinase PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000117266
Ensembl ENSG00000117266
GO Cellular Component GO:0005575 (cellular_component)
GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
Wikipedia PCTK3

Target Cross References - Protein

canSAR Q07002
Human Protein Atlas ENSG00000117266
IntAct Q07002
Guide to Pharmacology 1971
Open Targets ENSG00000117266
PharmGKB PA33097
Pharos Q07002 (Tbio)
UniProt Q07002 Q5VXQ2 Q6V3A2 Q6V3A3 Q96F90

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)