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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5276
Target Type SINGLE PROTEIN
Preferred Name 3-dehydroquinate dehydratase
Synonyms 3-dehydroquinase | 3-dehydroquinate dehydratase | Type II DHQase | aroQ
Organism Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
3-dehydroquinate dehydratase SINGLE PROTEIN P15474

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Molecular Function GO:0003855 (3-dehydroquinate dehydratase activity)
GO:0016829 (lyase activity)
GO Biological Process GO:0008652 (cellular amino acid biosynthetic process)
GO:0009073 (aromatic amino acid family biosynthetic process)
GO:0009423 (chorismate biosynthetic process)

Target Cross References - Protein

canSAR P15474
UniProt O33608 P15474

Target Cross References - Domain

InterPro IPR001874 (DHquinase_II.)
IPR018509 (DHquinase_II_CS.)
Pfam PF01220 (DHquinase_II)

Target Cross References - Structure

PDBe 1D0I 1GTZ 1GU0 1GU1 1V1J 2BT4 2CJF
CREDO 1D0I 1GTZ 1GU0 1GU1 1V1J 2BT4 2CJF
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