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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5258
Target Type SINGLE PROTEIN
Preferred Name CaM kinase I gamma
Synonyms CAMK1G | CLICK III | CLICK3 | CaM kinase I gamma | CaM kinase IG | CaM-KI gamma | CaMK-like CREB kinase III | CaMKI gamma | CaMKIG | Calcium/calmodulin-dependent protein kinase type 1G | VWS1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > camk protein kinase group > camk protein kinase camk1 family

Target Components

Component Description Relationship Accession
Calcium/calmodulin-dependent protein kinase type 1G SINGLE PROTEIN Q96NX5

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000008118
Ensembl ENSG00000008118
GO Cellular Component GO:0000139 (Golgi membrane)
GO:0005622 (intracellular)
GO:0005737 (cytoplasm)
GO:0005794 (Golgi apparatus)
GO:0005886 (plasma membrane)
GO:0005954 (calcium- and calmodulin-dependent protein kinase complex)
GO:0012505 (endomembrane system)
GO:0016020 (membrane)
GO:0043005 (neuron projection)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0003824 (catalytic activity)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0004683 (calmodulin-dependent protein kinase activity)
GO:0005516 (calmodulin binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0008152 (metabolic process)
GO:0016310 (phosphorylation)
GO:0018105 (peptidyl-serine phosphorylation)
GO:0018107 (peptidyl-threonine phosphorylation)
GO:0035556 (intracellular signal transduction)

Target Cross References - Protein

canSAR Q96NX5
Human Protein Atlas ENSG00000008118
IntAct Q96NX5
Guide to Pharmacology 1954
Open Targets ENSG00000008118
PharmGKB PA26049
Pharos Q96NX5 (Tchem)
UniProt Q86UH5 Q96NX5 Q9Y3J7

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)

Target Cross References - Structure

PDBe 2JAM
CREDO 2JAM
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