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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5166
Target Type SINGLE PROTEIN
Preferred Name Tyrosine-protein kinase V-ABL
Synonyms ABL | Tyrosine-protein kinase transforming protein Abl | V-abl
Organism Abelson murine leukemia virus
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > tk protein kinase group > tyrosine protein kinase abl family

Target Components

Component Description Relationship Accession
Tyrosine-protein kinase transforming protein Abl SINGLE PROTEIN P00521

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004713 (protein tyrosine kinase activity)
GO:0004715 (non-membrane spanning protein tyrosine kinase activity)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
GO:0018108 (peptidyl-tyrosine phosphorylation)

Target Cross References - Protein

canSAR P00521
IntAct P00521
UniProt P00521

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR000980 (SH2.)
IPR001245 (Ser-Thr/Tyr_kinase_cat_dom.)
IPR008266 (Tyr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR015015 (F-actin_binding.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR020635 (Tyr_kinase_cat_dom.)
IPR033221 (ABL1.)
IPR035837 (ABL_SH2.)
IPR036860 (SH2_dom_sf.)
Pfam PF00017 (SH2)
PF07714 (Pkinase_Tyr)
PF08919 (F_actin_bind)
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