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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5101
Target Type SINGLE PROTEIN
Preferred Name Arylamine N-acetyltransferase 1
Synonyms AAC1 | Arylamide acetylase 1 | Arylamine N-acetyltransferase 1 | MNAT | Monomorphic arylamine N-acetyltransferase | N-acetyltransferase type 1 | NAT-1 | NAT1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Arylamine N-acetyltransferase 1 SINGLE PROTEIN P18440

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000171428
Ensembl ENSG00000171428
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0004060 (arylamine N-acetyltransferase activity)
GO:0016407 (acetyltransferase activity)
GO:0016740 (transferase activity)
GO:0016746 (transferase activity, transferring acyl groups)
GO Biological Process GO:0006805 (xenobiotic metabolic process)
GO:0008152 (metabolic process)
Wikipedia N-acetyltransferase_1

Target Cross References - Protein

canSAR P18440
CGD Acetylation, NAT1-related
Human Protein Atlas ENSG00000171428
IntAct P18440
Open Targets ENSG00000171428
PharmGKB PA17
Reactome R-HSA-156582 (Acetylation.)
UniProt A8K4E7 O15159 O15300 P18440 Q546N1 Q96TE9

Target Cross References - Domain

InterPro IPR001447 (Arylamine_N-AcTrfase.)
Pfam PF00797 (Acetyltransf_2)

Target Cross References - Structure

PDBe 2IJA 2PQT
CREDO 2IJA 2PQT
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