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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5084
Target Type SINGLE PROTEIN
Preferred Name Casein kinase I isoform gamma-3
Synonyms CKI-gamma 3 | CSNK1G3 | Casein kinase I isoform gamma-3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > ck1 protein kinase group > ck1 protein kinase ck1 family > ck1 protein kinase ck1-g

Target Components

Component Description Relationship Accession
Casein kinase I isoform gamma-3 SINGLE PROTEIN Q9Y6M4

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000151292
Ensembl ENSG00000151292
GO Cellular Component GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006464 (cellular protein modification process)
GO:0006468 (protein phosphorylation)
GO:0006897 (endocytosis)
GO:0007165 (signal transduction)
GO:0008360 (regulation of cell shape)
GO:0016055 (Wnt signaling pathway)
GO:0016310 (phosphorylation)
GO:0018105 (peptidyl-serine phosphorylation)

Target Cross References - Protein

canSAR Q9Y6M4
Human Protein Atlas ENSG00000151292
IntAct Q9Y6M4
Guide to Pharmacology 2001
Open Targets ENSG00000151292
PharmGKB PA26956
Pharos Q9Y6M4 (Tbio)
UniProt A8K040 B4DSH2 B7Z9Q4 E7EVD0 Q86WZ7 Q9Y6M3 Q9Y6M4

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR022247 (Casein_kinase-1_gamma_C.)
Pfam PF00069 (Pkinase)
PF12605 (CK1gamma_C)

Target Cross References - Structure

PDBe 2CHL 2IZR 2IZS 2IZT 2IZU 4G16 4G17 4HGL 4HGS
CREDO 2CHL 2IZR 2IZS 2IZT 2IZU 4G16 4G17 4HGL 4HGS
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