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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5076
Target Type SINGLE PROTEIN
Preferred Name Histamine H3 receptor
Synonyms H3R | HH3R | HRH3 | Histamine H3 receptor
Organism Cavia porcellus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > histamine receptor

Target Components

Component Description Relationship Accession
Histamine H3 receptor SINGLE PROTEIN Q9JI35

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004969 (histamine receptor activity)
GO Biological Process GO:0001505 (regulation of neurotransmitter levels)
GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)

Target Cross References - Protein

canSAR Q9JI35
UniProt Q9JI35 Q9JI36

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR003980 (Histamine_H3_rcpt.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)
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