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ChEMBL

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Target Report Card

Target Name and Classification

Target ID CHEMBL5073
Target Type SINGLE PROTEIN
Preferred Name CaM kinase I delta
Synonyms CAMK1D | CAMKID | CKLiK | CaM kinase I delta | CaM kinase ID | CaM-KI delta | CaMKI delta | CaMKI-like protein kinase | CaMKID | Calcium/calmodulin-dependent protein kinase type 1D
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > camk protein kinase group > camk protein kinase camk1 family

Target Components

Component Description Relationship Accession
Calcium/calmodulin-dependent protein kinase type 1D SINGLE PROTEIN Q8IU85

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000183049
Ensembl ENSG00000183049
GO Cellular Component GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0003824 (catalytic activity)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0004683 (calmodulin-dependent protein kinase activity)
GO:0005516 (calmodulin binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0006954 (inflammatory response)
GO:0007399 (nervous system development)
GO:0008152 (metabolic process)
GO:0010976 (positive regulation of neuron projection development)
GO:0016310 (phosphorylation)
GO:0018105 (peptidyl-serine phosphorylation)
GO:0018107 (peptidyl-threonine phosphorylation)
GO:0032793 (positive regulation of CREB transcription factor activity)
GO:0035556 (intracellular signal transduction)
GO:0043065 (positive regulation of apoptotic process)
GO:0043066 (negative regulation of apoptotic process)
GO:0050766 (positive regulation of phagocytosis)
GO:0050773 (regulation of dendrite development)
GO:0060267 (positive regulation of respiratory burst)
GO:0071622 (regulation of granulocyte chemotaxis)
GO:0090023 (positive regulation of neutrophil chemotaxis)

Target Cross References - Protein

canSAR Q8IU85
Human Protein Atlas ENSG00000183049
IntAct Q8IU85
Guide to Pharmacology 1953
Open Targets ENSG00000183049
PharmGKB PA134992438
Pharos Q8IU85 (Tchem)
UniProt B0YIY0 Q8IU85 Q9HD31

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)

Target Cross References - Structure

PDBe 2JC6
CREDO 2JC6
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