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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5044
Target Type SINGLE PROTEIN
Preferred Name Serine/threonine-protein kinase Nek5
Synonyms NEK5 | Never in mitosis A-related kinase 5 | NimA-related protein kinase 5 | Serine/threonine-protein kinase Nek5
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > other protein kinase group > other protein kinase nek family

Target Components

Component Description Relationship Accession
Serine/threonine-protein kinase Nek5 SINGLE PROTEIN Q6P3R8

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000197168
Ensembl ENSG00000197168
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
GO:0051155 (positive regulation of striated muscle cell differentiation)
GO:2001056 (positive regulation of cysteine-type endopeptidase activity)

Target Cross References - Protein

canSAR Q6P3R8
Human Protein Atlas ENSG00000197168
IntAct Q6P3R8
Guide to Pharmacology 2120
Open Targets ENSG00000197168
PharmGKB PA31549
Pharos Q6P3R8 (Tdark)
UniProt Q5TAP5 Q6P3R8

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)
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