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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL5031
Target Type SINGLE PROTEIN
Preferred Name Beta-lactamase
Synonyms Beta-lactamase | Cephalosporinase | ampC
Organism Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Beta-lactamase SINGLE PROTEIN P24735

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0030288 (outer membrane-bounded periplasmic space)
GO:0042597 (periplasmic space)
GO Molecular Function GO:0008800 (beta-lactamase activity)
GO:0016787 (hydrolase activity)
GO Biological Process GO:0017001 (antibiotic catabolic process)
GO:0033252 (regulation of beta-lactamase activity)
GO:0046677 (response to antibiotic)

Target Cross References - Protein

canSAR P24735
UniProt P24735

Target Cross References - Domain

InterPro IPR001466 (Beta-lactam-related.)
IPR001586 (Beta-lactam_class-C_AS.)
IPR012338 (Beta-lactam/transpept-like.)
Pfam PF00144 (Beta-lactamase)

Target Cross References - Structure

PDBe 2WZX 2WZZ 3S1Y 3S22 4GZB 4HEF 4NK3 4OOY 4WYY 4WZ4 4X68
CREDO 2WZX 2WZZ 3S1Y 3S22 4GZB 4HEF 4NK3 4OOY 4WYY 4WZ4 4X68
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